Journey information
Overview: San Diego, CA to St. Louis, MO flight
Flights from San Diego, CA to St. Louis, MO depart on average 62 times per day, taking around 7h 56m. Cheap flight tickets for this journey start at $171 (€139) if you book in advance.
The earliest flight runs at 05:00, the last at 23:58. The fastest flight covers the 1560 miles (2512 km) distance in 5h 25m. January is the cheapest month to fly.
Distance 1560 miles (2512 km) |
Average flight duration 7h 56m |
Cheapest ticket price $171 (€139) |
Flights per day 62 |
Fastest flight 5h 25m |
Cheapest month January |
First flight 05:00 |
Last flight 23:58 |
The cheapest and fastest flights from San Diego, CA to St. Louis, MO
Cheapest price
$279
Average price
$519
Fastest journey
5 h 4 m
Average duration
5 h 46 m
Flights per day
59
Distance
2512 km
The best way to find a cheap flight ticket from San Diego, CA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Diego, CA to St. Louis, MO will cost around $519 if you buy it on the day, but the cheapest tickets can be found for only $279.
It's difficult to get from San Diego, CA to St. Louis, MO without transferring at least once.
AA3227 · AA226907:10AM8h03San Diego International Airport05:13PMSt. Louis Lambert International Airport$2791One-way1 transfer
AA1494+
AA488906:20AM7h11San Diego International Airport03:31PMSt. Louis Lambert International Airport$2791One-way1 transfer
AA3126 · AA247510:00PM8h35San Diego International Airport08:35AMSt. Louis Lambert International Airport$2791One-way1 transfer
AA1646 · AA226908:00AM7h13San Diego International Airport05:13PMSt. Louis Lambert International Airport$2791One-way1 transfer
AA1950 · AA204304:55PM5h04San Diego International Airport11:59PMSt. Louis Lambert International Airport$2791One-way1 transfer
AA1950 · AA204304:55PM5h04San Diego International Airport11:59PMSt. Louis Lambert International Airport$2791One-way1 transfer
AA1694 · AA230306:24AM5h23San Diego International Airport01:47PMSt. Louis Lambert International Airport$2791One-way1 transfer
UA5515 · UA142212:57PM5h57McClellan–Palomar Airport08:54PMSt. Louis Lambert International Airport$10861One-way1 transfer
UA2476 · UA131508:45AM6h11San Diego International Airport04:56PMSt. Louis Lambert International Airport$3351One-way1 transfer
AA2535 · AA226909:00AM6h13San Diego International Airport05:13PMSt. Louis Lambert International Airport$3401One-way1 transfer
Travel Information
Compare train, bus, and flight for San Diego, CA to St. Louis, MO
Omio recommends booking the train as it is the most popular option from San Diego, CA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $174. For those with little time consider booking a flight which can get you there in 7h 56m. The ticket price range depends on the travel mode: a bus costs an average of $174, and a train costs an average of $299.
Distance: 1560 miles (2512 km)
Compare flight with
| Flight | Most popular Train | Bus |
|---|---|---|
$266 Average price | $316 Average price | $251 Average price Cheapest |
10h 56m Average total duration Fastest 7h 56m Onboard + 3h 0m Additional time* | 46h 46m Average total duration 46h 16m Onboard + 30m Additional time* | 50h 35m Average total duration 50h 5m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
San Diego, CA to St. Louis, MO flight times
The table below shows live departures for San Diego, CA to St. Louis, MO flights for today, Wednesday, April 1. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:40 PM San Diego, CA | 8h32 | 5:12 AM St. Louis, MO | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Diego, CA to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: San Diego, CA to St. Louis, MO Flight
Find answers to the most common questions about traveling from San Diego, CA to St. Louis, MO by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

- St. Louis Mardi Gras, a vibrant celebration featuring parades, live music, and festive activities in the Soulard neighborhood
- St. Louis Art Fair, an annual event showcasing local and national artists with art exhibits, live performances, and culinary delights
- Fair St. Louis, a multi-day Independence Day festival with fireworks, concerts, and family-friendly activities along the Gateway Arch.
- Independence Day, vibrant fireworks and festive celebrations throughout the city
- Labor Day, pleasant weather and various outdoor activities
- Thanksgiving, a time for family gatherings with a charming autumn atmosphere.
popular airports
Popular airports from San Diego, CA to St. Louis, MO
- Free Wi-Fi available throughout the airport.
- Shops in terminals 1 and 2, including Duty-Free and Hudson News.
- Parking available, price varies.
- Restaurants in terminals 1 and 2, including fast food and sit-down options like The Counter and Phil's BBQ
- Available outside the terminal.
- Elevators, ramps
- Available throughout the airport.
- Hotels nearby, Sheraton San Diego Hotel & Mari within walking distance.
- Showers available at the Airspace Lounge, access fee required.
- Lounges available, including United Club and Airspace Lounge.
- Lost and Found located in terminal 2 East, baggage claim area.
- Car rental services available at Rental Car Center, free shuttle from terminals
- Bus Route 992, Airport Station, 4.8 km
- Free Wi-Fi available throughout the airport.
- Shops in both terminals, including Hudson News and Tech on the Go.
- Parking available with short-term and long-term options, approximately 1.42€ ($1.50) per hour.
- Restaurants in both terminals, including fast food and sit-down options like Starbucks and Chili's
- Available outside the terminal.
- Elevators, ramps
- Available throughout both terminals.
- Hotels nearby, such as Marriott St. Louis Airport within walking distance.
- Showers available in some lounges, access may require lounge fee.
- Lounges available, including American Airlines Admirals Club.
- Lost and Found located in terminal 1, contact airport for details.
- Car rental services available, including Hertz and Enterprise in terminal 1
- MetroLink Red Line, Lambert Airport terminal 1 & 2 stations, 35 minutes
More options for your journey from San Diego, CA to St. Louis, MO
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