The cheapest and fastest buses from Charlotte, NC to St. Louis, MO
Cheapest price
$146
Average price
$146
Fastest journey
15 h 35 m
Average duration
15 h 35 m
Buses per day
1
Distance
913 km
The best way to find a cheap bus ticket from Charlotte, NC to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charlotte, NC to St. Louis, MO will cost around $146 if you buy it on the day, but the cheapest tickets can be found for only $146.
It's difficult to get from Charlotte, NC to St. Louis, MO without transferring at least once.
5:35 PM15h35Charlotte, NC9:10 AMSt. Louis, MO$1461One-way1 transfer
5:35 PM15h35Charlotte, NC9:10 AMSt. Louis, MO$1461One-way1 transfer
Travel Information
Compare train, bus, and flight for Charlotte, NC to St. Louis, MO
Omio recommends booking the flight as it is the most popular option from Charlotte, NC to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $127. For those with little time consider booking a flight which can get you there in 3h 58m. The ticket price range depends on the travel mode: a bus costs an average of $127, and a train costs an average of $395.
Distance: 567 miles (913 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$185 Average price Cheapest | $363 Average price | $601 Average price |
16h 50m Average total duration 16h 20m Onboard + 30m Additional time* | 6h 58m Average total duration Fastest 3h 58m Onboard + 3h 0m Additional time* | 39h 18m Average total duration 38h 48m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Charlotte, NC to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 06
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Apr 12
Why should you book Charlotte, NC to St. Louis, MO buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of Barons Bus to find the best option for your trip from Charlotte, NC to St. Louis, MO.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Charlotte, NC to St. Louis, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Charlotte, NC to St. Louis, MO.
Journey information
Overview: Bus from Charlotte, NC to St. Louis, MO
Buses from Charlotte, NC to St. Louis, MO run on average 7 times per day, taking around 16h 20m. Cheap bus tickets for this journey start at $127 (€104) if you book in advance.
The earliest bus runs at 00:55, the last at 23:40. The fastest bus covers the 567 miles (913 km) distance in 16h 35m.
Distance 567 miles (913 km) |
Average bus duration 16h 20m |
Cheapest ticket price $127 (€104) |
Buses per day 7 |
Fastest bus 16h 35m |
First bus 12:55 AM |
Last bus 11:40 PM |
Bus providers: Greyhound, Barons Bus from Charlotte, NC to St. Louis, MOYou can travel by bus between Charlotte, NC to St. Louis, MO with Greyhound, Barons Bus for as low as $127 (€104). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
Barons Bus
FAQs: Bus from Charlotte, NC to St. Louis, MO
Find answers to the most common questions about traveling from Charlotte, NC to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Charlotte, NC to St. Louis, MO
More options for your journey from Charlotte, NC to St. Louis, MO
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