The cheapest and fastest buses from Florence to Karlsruhe
Cheapest price
$49
Average price
$83
Fastest journey
14 h 16 m
Average duration
14 h 45 m
Buses per day
3
Distance
622 km
The best way to find a cheap bus ticket from Florence to Karlsruhe is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence to Karlsruhe will cost around $83 if you buy it on the day, but the cheapest tickets can be found for only $49.
Of the 3 buses that leave Florence for Karlsruhe on Mon, Apr 06, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Apr 06 the direct buses cover the 622 km distance in an average of 14 h 45 m but if you time it right, some buses will get you there in just 14 h 16 m .
On Mon, Apr 06 the slowest buses will take 15 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
7:00 PM15h10Florence10:10 AMKarlsruhe$491One-way0 transfers
11:50 AM14h50Florence2:40 AMKarlsruhe$991One-way0 transfers
11:05 PM14h16Florence1:21 PMKarlsruhe$1031One-way0 transfers
11:05 PM14h16Florence1:21 PMKarlsruhe$1031One-way0 transfers
11:50 AM14h50Florence2:40 AMKarlsruhe$991One-way0 transfers
7:00 PM15h10Florence10:10 AMKarlsruhe$491One-way0 transfers
Travel Information
Compare train and bus for Florence to Karlsruhe
Omio recommends booking the bus as it is the most popular option from Florence to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from $44. For those with little time consider booking a train which can get you there in 8h 59m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $44, and a train costs an average of $236.
Distance: 386 miles (622 km)
Compare bus with
Most popular Bus | Train |
|---|---|
$69 Average price Cheapest | $256 Average price |
13h 48m Average total duration 13h 18m Onboard + 30m Additional time* | 9h 29m Average total duration Fastest 8h 59m Onboard + 30m Additional time* |
0.6 - 1.6kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Florence to Karlsruhe Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:05AM | Arrival Time 03:00PM | Duration 14h55 | Departure days Wed | Cheapest price $125 |
Operator FlixBus | Departure Time 12:30AM | Arrival Time 05:30PM | Duration 17h00 | Departure days Wed | Cheapest price $99 |
Operator FlixBus | Departure Time 01:50AM | Arrival Time 03:35PM | Duration 13h45 | Departure days Wed | Cheapest price $170 |
Operator Marino Autolinee | Departure Time 02:15AM | Arrival Time 05:05PM | Duration 14h50 | Departure days Wed | Cheapest price $177 |
Operator FlixBus | Departure Time 02:15AM | Arrival Time 07:35PM | Duration 17h20 | Departure days Wed | Cheapest price $117 |
Operator FlixBus | Departure Time 04:55AM | Arrival Time 12:00AM | Duration 19h05 | Departure days Wed | Cheapest price $117 |
Operator FlixBus | Departure Time 09:50AM | Arrival Time 01:35AM | Duration 15h45 | Departure days Wed | Cheapest price $104 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 03:10AM | Duration 15h55 | Departure days Wed | Cheapest price $136 |
Operator FlixBus | Departure Time 11:55AM | Arrival Time 03:10AM | Duration 15h15 | Departure days Wed | Cheapest price $162 |
Operator FlixBus | Departure Time 01:35PM | Arrival Time 03:45AM | Duration 14h10 | Departure days Wed | Cheapest price $101 |
Operator FlixBus | Departure Time 02:20PM | Arrival Time 06:10AM | Duration 15h50 | Departure days Wed | Cheapest price $126 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 08:20AM | Duration 15h35 | Departure days Wed | Cheapest price $135 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 11:10AM | Duration 15h10 | Departure days Wed | Cheapest price $86 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 03:55PM | Duration 17h55 | Departure days Wed | Cheapest price $101 |
Operator FlixBus | Departure Time 10:20PM | Arrival Time 03:00PM | Duration 16h40 | Departure days Wed | Cheapest price $121 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 03:00PM | Duration 15h20 | Departure days Wed | Cheapest price $121 |
Live departures
Florence to Karlsruhe bus times
The table below shows live departures for Florence to Karlsruhe buses for today, Sunday, April 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:00 PM Florence | 15h10 | 10:10 AM Karlsruhe | 0 transfersDirect | |
| Monday, April 6 | |||||
![]() | 11:50 AM Florence | 14h50 | 2:40 AM Karlsruhe | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence to Karlsruhe by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 06
Apr 07
Apr 08
Apr 09
Apr 10
Apr 11
Apr 12
Why should you book Florence to Karlsruhe buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Infobus or Itabus to find the best option for your trip from Florence to Karlsruhe.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Florence to Karlsruhe.
Why book with Omio over Wanderu, Trainline or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Infobus or Itabus to find the best option for your trip from Florence to Karlsruhe.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Florence to Karlsruhe.
Journey information
Overview: Bus from Florence to Karlsruhe
Buses from Florence to Karlsruhe run on average 14 times per day, taking around 13h 18m. Cheap bus tickets for this journey start at $44 (€36) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 386 miles (622 km) distance in 13h 50m.
Distance 386 miles (622 km) |
Average bus duration 13h 18m |
Cheapest ticket price $44 (€36) |
Buses per day 14 |
Direct buses 1 |
Fastest bus 13h 50m |
First bus 12:05 AM |
Last bus 11:55 PM |
Bus providers: FlixBus, Infobus, Itabus from Florence to KarlsruheYou can travel by bus between Florence to Karlsruhe with FlixBus, Infobus, Itabus for as low as $44 (€36). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
Itabus
FAQs: Bus from Florence to Karlsruhe
Find answers to the most common questions about traveling from Florence to Karlsruhe by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Karlsruhe, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Florence to Karlsruhe
- 06:00-22:00
- Free Wi-Fi
- Elevators, ramps
- Available in the station.
- Bus: 37, 72 Tram: T1
- 06:00-21:00
- Free Wi-Fi
- Available near the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 12, 13, 17 Train: Firenze Santa Maria Novella
More options for your journey from Florence to Karlsruhe
Here are some other resources that might have the information you need

