The cheapest and fastest buses from Florence, SC to Wilmington, DE
Cheapest price
$99
Average price
$99
Fastest journey
13 h 25 m
Average duration
13 h 25 m
Buses per day
1
Distance
722 km
The best way to find a cheap bus ticket from Florence, SC to Wilmington, DE is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Wilmington, DE will cost around $99 if you buy it on the day, but the cheapest tickets can be found for only $99.
Of the 1 buses that leave Florence, SC for Wilmington, DE on Thu, Apr 02, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Apr 02 the direct buses cover the 722 km distance in an average of 13 h 25 m but if you time it right, some buses will get you there in just 13 h 25 m .
On Thu, Apr 02 the slowest buses will take 13 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
09:30PM13h25Florence, SC10:55AMWilmington, DE$991One-way0 transfers
09:30PM13h25Florence, SC10:55AMWilmington, DE$991One-way0 transfers
Travel Information
Compare train and bus for Florence, SC to Wilmington, DE
Omio recommends booking the train as it is the most popular option from Florence, SC to Wilmington, DE among Omio's users. If you are prioritising price take the bus with prices starting from $72. For those with little time consider booking a train which can get you there in 10h 15m. The ticket price range depends on the travel mode: a bus costs an average of $72, and a train costs an average of $121.
Distance: 448 miles (722 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
$129 Average price Cheapest | $146 Average price |
13h 55m Average total duration 13h 25m Onboard + 30m Additional time* | 10h 45m Average total duration Fastest 10h 15m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Florence, SC to Wilmington, DE bus times
The table below shows live departures for Florence, SC to Wilmington, DE buses for today, Wednesday, April 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:30 PM Florence, SC | 13h25 | 5:55 AM Wilmington, DE | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence, SC to Wilmington, DE by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 02
Apr 03
Apr 04
Apr 05
Apr 06
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Apr 08
Journey information
Overview: Bus from Florence, SC to Wilmington, DE
Buses from Florence, SC to Wilmington, DE run on average 2 times per day, taking around 13h 25m. Cheap bus tickets for this journey start at $72 (€58) if you book in advance.
The earliest bus runs at 00:05, the last at 21:25. The fastest bus covers the 448 miles (722 km) distance in 13h 25m.
Distance 448 miles (722 km) |
Average bus duration 13h 25m |
Cheapest ticket price $72 (€58) |
Buses per day 2 |
Fastest bus 13h 25m |
First bus 00:05 |
Last bus 21:25 |
FAQs: Bus from Florence, SC to Wilmington, DE
Find answers to the most common questions about traveling from Florence, SC to Wilmington, DE by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Wilmington, DE, this guide helps you travel smarter and with confidence.

- Nemours Estate, a grand 300-acre estate featuring formal French gardens and a classical mansion
- Hagley Museum and Library, a historical site showcasing the early American industrial revolution with exhibits and scenic grounds
- Delaware Art Museum, home to a diverse collection of American art and illustration, including works by the Brandywine School
- Brandywine Zoo, a small zoo located in Brandywine Park featuring a variety of animals and educational programs
- Rockford Park, a historic park offering scenic views, walking trails, and the iconic Rockford Tower.
- Riverfront Wilmington, a vibrant area with dining, shopping, and scenic views along the Christina River
- Wilmington and Western Railroad, offering scenic train rides through the picturesque countryside
- The Grand Opera House, a historic venue hosting a variety of performances and events
- Delaware Children's Museum, an interactive museum with engaging exhibits for kids
- Alapocas Run State Park, perfect for hiking, rock climbing, and enjoying nature.
popular bus stations
Popular bus stations from Florence, SC to Wilmington, DE
Most popular bus connections from Florence, SC
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