Why should you book Frederick, MD to Wilmington, DE buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of BayRunner Shuttle to find the best option for your trip from Frederick, MD to Wilmington, DE.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Frederick, MD to Wilmington, DE
Buses from Frederick, MD to Wilmington, DE run on average 4 times per day, taking around 7h 16m. Cheap bus tickets for this journey start at $136 (€111) if you book in advance.
The earliest bus runs at 00:30, the last at 21:25. The fastest bus covers the 101 miles (164 km) distance in 5h 30m.
Distance 101 miles (164 km) |
Average bus duration 7h 16m |
Cheapest ticket price $136 (€111) |
Buses per day 4 |
Fastest bus 5h 30m |
First bus 12:30 AM |
Last bus 9:25 PM |
Bus providers: Greyhound, BayRunner Shuttle from Frederick, MD to Wilmington, DEYou can travel by bus between Frederick, MD to Wilmington, DE with Greyhound, BayRunner Shuttle for as low as $136 (€111). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
BayRunner Shuttle
FAQs: Bus from Frederick, MD to Wilmington, DE
Find answers to the most common questions about traveling from Frederick, MD to Wilmington, DE by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Wilmington, DE, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Nemours Estate, a grand 300-acre estate featuring formal French gardens and a classical mansion
- Hagley Museum and Library, a historical site showcasing the early American industrial revolution with exhibits and scenic grounds
- Delaware Art Museum, home to a diverse collection of American art and illustration, including works by the Brandywine School
- Brandywine Zoo, a small zoo located in Brandywine Park featuring a variety of animals and educational programs
- Rockford Park, a historic park offering scenic views, walking trails, and the iconic Rockford Tower.
- Riverfront Wilmington, a vibrant area with dining, shopping, and scenic views along the Christina River
- Wilmington and Western Railroad, offering scenic train rides through the picturesque countryside
- The Grand Opera House, a historic venue hosting a variety of performances and events
- Delaware Children's Museum, an interactive museum with engaging exhibits for kids
- Alapocas Run State Park, perfect for hiking, rock climbing, and enjoying nature.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Frederick, MD to Wilmington, DE
Most popular bus connections from Frederick, MD
More options for your journey from Frederick, MD to Wilmington, DE
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