The cheapest and fastest buses from Greenville, SC to Syracuse, NY
Cheapest price
$182
Average price
$202
Fastest journey
21 h 55 m
Average duration
22 h 40 m
Buses per day
3
Distance
1059 km
The best way to find a cheap bus ticket from Greenville, SC to Syracuse, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Syracuse, NY will cost around $202 if you buy it on the day, but the cheapest tickets can be found for only $182.
It's difficult to get from Greenville, SC to Syracuse, NY without transferring at least 2 times.
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FlixBus7:10 AM21h55Greenville, Woodruff Rd ("Raceway" gas station), SC5:05 AMSyracuse, Walsh Cir (Syracuse Bus Station), NY$1821One-way2 transfers
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undefined · undefined12:15 PM23h05Greenville, Woodruff Rd ("Raceway" gas station), SC11:20 AMSyracuse, Walsh Cir (Syracuse Bus Station), NY$1881One-way2 transfers
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FlixBus4:15 PM23h00Greenville, Woodruff Rd ("Raceway" gas station), SC3:15 PMSyracuse, Walsh Cir (Syracuse Bus Station), NY$2361One-way2 transfers
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FlixBus7:10 AM21h55Greenville, Woodruff Rd ("Raceway" gas station), SC5:05 AMSyracuse, Walsh Cir (Syracuse Bus Station), NY$1821One-way2 transfers
FlixBus+
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FlixBus4:15 PM23h00Greenville, Woodruff Rd ("Raceway" gas station), SC3:15 PMSyracuse, Walsh Cir (Syracuse Bus Station), NY$2361One-way2 transfers
FlixBus+
undefined · undefined12:15 PM23h05Greenville, Woodruff Rd ("Raceway" gas station), SC11:20 AMSyracuse, Walsh Cir (Syracuse Bus Station), NY$1881One-way2 transfers
Travel Information
Compare bus and flight for Greenville, SC to Syracuse, NY
Omio recommends booking the flight as it is the most popular option from Greenville, SC to Syracuse, NY among Omio's users. If you are prioritising price take the bus with prices starting from $144. For those with little time consider booking a flight which can get you there in 6h 14m. The ticket price range depends on the travel mode: a bus costs an average of $144, and a flight costs an average of $365.
Distance: 658 miles (1059 km)
Compare bus with
| Bus | Most popular Flight |
|---|---|
$174 Average price Cheapest | $418 Average price |
22h 50m Average total duration 22h 20m Onboard + 30m Additional time* | 9h 14m Average total duration Fastest 6h 14m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Greenville, SC to Syracuse, NY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:10AM | Arrival Time 05:05AM | Duration 21h55 | Departure days Fri, Sat | Cheapest price $172 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 11:20AM | Duration 23h05 | Departure days Fri, Sat | Cheapest price $172 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 03:15PM | Duration 23h00 | Departure days Fri, Sat | Cheapest price $180 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 07:30PM | Duration 21h30 | Departure days Fri | Cheapest price $172 |
Live departures
Greenville, SC to Syracuse, NY bus times
The table below shows live departures for Greenville, SC to Syracuse, NY buses for today, Friday, April 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
undefined · undefined+ FlixBus | 11:10 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 21h55 | 9:05 AM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 2 transfers | |
FlixBus+ undefined · undefined | 4:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 23h05 | 3:20 PM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 2 transfers | |
FlixBus+ + FlixBus | 8:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 23h00 | 7:15 PM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 2 transfers | |
| Saturday, April 4 | |||||
FlixBus · FlixBus+![]() | 2:00 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 21h30 | 11:30 PM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Journey information
Overview: Bus from Greenville, SC to Syracuse, NY
Buses from Greenville, SC to Syracuse, NY run on average 4 times per day, taking around 22h 20m. Cheap bus tickets for this journey start at $144 (€117) if you book in advance.
The earliest bus runs at 07:25, the last at 22:00. The fastest bus covers the 658 miles (1059 km) distance in 21h 40m.
Distance 658 miles (1059 km) |
Average bus duration 22h 20m |
Cheapest ticket price $144 (€117) |
Buses per day 4 |
Fastest bus 21h 40m |
First bus 7:25 AM |
Last bus 10:00 PM |
FAQs: Bus from Greenville, SC to Syracuse, NY
Find answers to the most common questions about traveling from Greenville, SC to Syracuse, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, NY, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Greenville, SC to Syracuse, NY
Most popular bus connections from Greenville, SC
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