The cheapest and fastest buses from Karlsruhe to Milan
Cheapest price
$80
Average price
$135
Fastest journey
7 h 20 m
Average duration
8 h
Buses per day
10
Distance
398 km
The best way to find a cheap bus ticket from Karlsruhe to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Milan will cost around $135 if you buy it on the day, but the cheapest tickets can be found for only $80.
Of the 10 buses that leave Karlsruhe for Milan on Fri, Apr 03, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Apr 03 the direct buses cover the 398 km distance in an average of 8 h but if you time it right, some buses will get you there in just 7 h 20 m .
On Fri, Apr 03 the slowest buses will take 8 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
254*9:30 AM11h10Karlsruhe, Hinterm Hauptbahnhof (Südeingang)8:40 PMMilano, San Donato - Settore B (Viale Giuseppe Impastato)$801One-way0 transfers
FlixBus8:10 PM8h55Karlsruhe Hbf5:05 AMMilano, Autostazione Lampugnano$921One-way0 transfers
FlixBus11:00 PM8h10Karlsruhe Hbf7:10 AMMilano, Autostazione Lampugnano$1011One-way0 transfers
FlixBus11:40 PM8h25Karlsruhe Hbf8:05 AMMilano, Autostazione Lampugnano$1031One-way0 transfers
FlixBus11:05 AM8h10Karlsruhe Hbf7:15 PMMilano, Autostazione Lampugnano$1171One-way0 transfers
FlixBus9:30 AM7h20Karlsruhe Hbf4:50 PMMilano, Autostazione Lampugnano$1361One-way0 transfers
FlixBus3:20 AM7h55Karlsruhe Hbf11:15 AMMilano, Autostazione Lampugnano$1361One-way0 transfers
FlixBus11:00 PM8h10Karlsruhe Hbf7:10 AMMilano, Autostazione Lampugnano$1011One-way0 transfers
FlixBus11:05 AM8h10Karlsruhe Hbf7:15 PMMilano, Autostazione Lampugnano$1171One-way0 transfers
FlixBus11:40 PM8h25Karlsruhe Hbf8:05 AMMilano, Autostazione Lampugnano$1031One-way0 transfers
Travel Information
Compare train and bus for Karlsruhe to Milan
Omio recommends booking the train as it is the most popular option from Karlsruhe to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a train which can get you there in 6h 26m. The ticket price range depends on the travel mode: a bus costs an average of $24, and a train costs an average of $76.
Distance: 247 miles (398 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
$54 Average price Cheapest | $175 Average price |
11h 13m Average total duration 10h 43m Onboard + 30m Additional time* | 6h 56m Average total duration Fastest 6h 26m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Karlsruhe to Milan Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar Bus | Departure Time 12:25AM | Arrival Time 09:25PM | Duration 21h00 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $95 |
Operator FlixBus | Departure Time 03:20AM | Arrival Time 11:15AM | Duration 7h55 | Departure days Everyday | Cheapest price $86 |
Operator FlixBus | Departure Time 07:40AM | Arrival Time 05:25PM | Duration 9h45 | Departure days Mon, Tue, Sat, Sun | Cheapest price $97 |
Operator Marino Autolinee | Departure Time 09:30AM | Arrival Time 08:40PM | Duration 11h10 | Departure days Fri | Cheapest price $80 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 04:50PM | Duration 7h20 | Departure days Everyday | Cheapest price $64 |
Operator FlixBus | Departure Time 11:05AM | Arrival Time 07:15PM | Duration 8h10 | Departure days Everyday | Cheapest price $83 |
Operator BlaBlaCar Bus | Departure Time 11:15AM | Arrival Time 06:00AM | Duration 18h45 | Departure days Fri, Sun | Cheapest price $64 |
Operator FlixBus | Departure Time 08:10PM | Arrival Time 05:05AM | Duration 8h55 | Departure days Everyday | Cheapest price $66 |
Operator BlaBlaCar Bus | Departure Time 09:05PM | Arrival Time 05:20PM | Duration 20h15 | Departure days Mon, Thu, Fri, Sun | Cheapest price $113 |
Operator FlixBus | Departure Time 11:00PM | Arrival Time 07:10AM | Duration 8h10 | Departure days Everyday | Cheapest price $64 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 08:05AM | Duration 8h25 | Departure days Mon, Fri, Sat, Sun | Cheapest price $74 |
Live departures
Karlsruhe to Milan bus times
The table below shows live departures for Karlsruhe to Milan buses for tomorrow, Thursday, April 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 1:20 AM Karlsruhe Hbf | 7h55 | 9:15 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
254* | 7:30 AM Karlsruhe, Hinterm Hauptbahnhof (Südeingang) | 11h10 | 6:40 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 7:30 AM Karlsruhe Hbf | 7h20 | 2:50 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 9:05 AM Karlsruhe Hbf | 8h10 | 5:15 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
34153 · 4751 | 9:15 AM Karlsruhe, Hinterm Hauptbahnhof (Südeingang) | 18h45 | 4:00 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus | 6:10 PM Karlsruhe Hbf | 8h55 | 3:05 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
51510 · 4767 | 7:05 PM Karlsruhe, Hinterm Hauptbahnhof (Südeingang) | 17h00 | 12:05 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus | 9:00 PM Karlsruhe Hbf | 8h10 | 5:10 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 9:40 PM Karlsruhe Hbf | 8h25 | 6:05 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Karlsruhe to Milan by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 03
Apr 04
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Apr 06
Apr 07
Apr 08
Apr 09
Apr 10
Apr 11
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Apr 17
Apr 18
Apr 19
Apr 20
Apr 21
Apr 22
Apr 23
Why should you book Karlsruhe to Milan buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus or Marino Autolinee to find the best option for your trip from Karlsruhe to Milan.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Karlsruhe to Milan.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus or Marino Autolinee to find the best option for your trip from Karlsruhe to Milan.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Karlsruhe to Milan.
Journey information
Overview: Bus from Karlsruhe to Milan
Buses from Karlsruhe to Milan run on average 7 times per day, taking around 10h 43m. Cheap bus tickets for this journey start at $24 (€19) if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 247 miles (398 km) distance in 7h 20m.
Distance 247 miles (398 km) |
Average bus duration 10h 43m |
Cheapest ticket price $24 (€19) |
Buses per day 7 |
Direct buses 6 |
Fastest bus 7h 20m |
First bus 12:15 AM |
Last bus 11:55 PM |
Bus providers: FlixBus, BlaBlaCar Bus, Marino Autolinee from Karlsruhe to MilanYou can travel by bus between Karlsruhe to Milan with FlixBus, BlaBlaCar Bus, Marino Autolinee for as low as $24 (€19). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Marino Autolinee
BlaBlaCar Bus
FAQs: Bus from Karlsruhe to Milan
Find answers to the most common questions about traveling from Karlsruhe to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Duomo di Milano, an iconic Gothic cathedral known for its intricate facade and panoramic rooftop views
- Galleria Vittorio Emanuele II, a historic shopping arcade featuring luxury brands and elegant architecture
- Castello Sforzesco, a Renaissance fortress housing museums and art collections
- Santa Maria delle Grazie, a church famous for housing Leonardo da Vinci's The Last Supper
- Teatro alla Scala, a world-renowned opera house celebrated for its exceptional acoustics and performances.
- Visit the Duomo di Milano, an iconic Gothic cathedral with stunning architecture and panoramic rooftop views
- Explore The Last Supper, Leonardo da Vinci's renowned mural located in the Convent of Santa Maria delle Grazie
- Stroll through Galleria Vittorio Emanuele II, a historic shopping arcade with luxury boutiques and elegant cafes
- Discover Sforza Castle, a grand fortress housing several museums and art collections
- Relax in Sempione Park, a large green space perfect for leisurely walks and picnics near the city center.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Karlsruhe to Milan
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
Most popular bus connections from Karlsruhe
More options for your journey from Karlsruhe to Milan
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