The cheapest and fastest buses from La Mesa, CA to Los Angeles, CA
Cheapest price
$42
Average price
$67
Fastest journey
2 h
Average duration
2 h 20 m
Buses per day
24
Distance
182 km
The best way to find a cheap bus ticket from La Mesa, CA to Los Angeles, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from La Mesa, CA to Los Angeles, CA will cost around $67 if you buy it on the day, but the cheapest tickets can be found for only $42.
Of the 24 buses that leave La Mesa, CA for Los Angeles, CA on Mon, Apr 06, 23 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Apr 06 the direct buses cover the 182 km distance in an average of 2 h 20 m but if you time it right, some buses will get you there in just 2 h .
On Mon, Apr 06 the slowest buses will take 2 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus8:20 AM3h00San Diego, Congress Street (Old Town Park), CA11:20 AMLos Angeles, Cesar E Chavez / Vignes, CA$421One-way0 transfers
FlixBus9:50 AM2h55La Jolla, UCSD Health La Jolla Station, CA12:45 PMLos Angeles, Cesar E Chavez / Vignes, CA$421One-way0 transfers
6:45 AM3h55San Diego, Congress Street (Old Town Park), CA10:40 AMLos Angeles, Patsaouras Transit Plaza (Union Station), CA$421One-way0 transfers
7:35 PM2h45San Diego, Congress Street (Old Town Park), CA10:20 PMLos Angeles, Patsaouras Transit Plaza (Union Station), CA$421One-way0 transfers
FlixBus8:20 AM2h25San Diego, Congress Street (Old Town Park), CA10:45 AMDowney, Stonewood Center (251 Stonewood St), CA$421One-way0 transfers
FlixBus8:45 AM2h00La Jolla, UCSD Health La Jolla Station, CA10:45 AMDowney, Stonewood Center (251 Stonewood St), CA$421One-way0 transfers
FlixBus8:20 AM2h25San Diego, Congress Street (Old Town Park), CA10:45 AMDowney, Stonewood Center (251 Stonewood St), CA$421One-way0 transfers
09:51 AM2h25San Diego, CA12:16 PMCommerce, CA$1071One-way0 transfers
03:51 PM2h25San Diego, CA6:16 PMCommerce, CA$1071One-way0 transfers
011:51 AM2h25San Diego, CA2:16 PMCommerce, CA$1071One-way0 transfers
Travel Information
Compare bus, train, and flight for La Mesa, CA to Los Angeles, CA
Omio recommends booking the train as it is the most popular option from La Mesa, CA to Los Angeles, CA among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a train which can get you there in 2h 49m. The ticket price range depends on the travel mode: a bus costs an average of $24, and a flight costs an average of $185.
Distance: 113 miles (182 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$33 Average price Cheapest | $39 Average price | $294 Average price |
4h 14m Average total duration 3h 44m Onboard + 30m Additional time* | 3h 19m Average total duration Fastest 2h 49m Onboard + 30m Additional time* | 13h 38m Average total duration 10h 38m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
La Mesa, CA to Los Angeles, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Infobus | Departure Time 06:30AM | Arrival Time 09:00AM | Duration 2h30 | Departure days Mon | Cheapest price $75 |
Operator Greyhound | Departure Time 06:45AM | Arrival Time 10:40AM | Duration 3h55 | Departure days Mon | Cheapest price $42 |
Operator FlixBus | Departure Time 07:35AM | Arrival Time 11:35AM | Duration 4h00 | Departure days Mon | Cheapest price $48 |
Operator Infobus | Departure Time 07:51AM | Arrival Time 10:16AM | Duration 2h25 | Departure days Mon | Cheapest price $107 |
Operator FlixBus | Departure Time 07:55AM | Arrival Time 11:35AM | Duration 3h40 | Departure days Mon | Cheapest price $48 |
Operator FlixBus | Departure Time 08:20AM | Arrival Time 11:20AM | Duration 3h00 | Departure days Mon | Cheapest price $42 |
Operator FlixBus | Departure Time 08:45AM | Arrival Time 10:45AM | Duration 2h00 | Departure days Mon | Cheapest price $42 |
Operator FlixBus | Departure Time 09:25AM | Arrival Time 12:45PM | Duration 3h20 | Departure days Mon | Cheapest price $42 |
Operator FlixBus | Departure Time 09:50AM | Arrival Time 12:45PM | Duration 2h55 | Departure days Mon | Cheapest price $42 |
Operator Infobus | Departure Time 09:51AM | Arrival Time 12:16PM | Duration 2h25 | Departure days Mon | Cheapest price $107 |
Operator Infobus | Departure Time 10:45AM | Arrival Time 01:15PM | Duration 2h30 | Departure days Mon | Cheapest price $75 |
Operator Infobus | Departure Time 11:30AM | Arrival Time 02:00PM | Duration 2h30 | Departure days Mon | Cheapest price $75 |
Operator Infobus | Departure Time 11:51AM | Arrival Time 02:16PM | Duration 2h25 | Departure days Mon | Cheapest price $107 |
Operator FlixBus | Departure Time 01:10PM | Arrival Time 04:55PM | Duration 3h45 | Departure days Mon | Cheapest price $42 |
Operator FlixBus | Departure Time 01:35PM | Arrival Time 04:55PM | Duration 3h20 | Departure days Mon | Cheapest price $42 |
Operator Infobus | Departure Time 01:51PM | Arrival Time 04:16PM | Duration 2h25 | Departure days Mon | Cheapest price $107 |
Operator Infobus | Departure Time 03:51PM | Arrival Time 06:16PM | Duration 2h25 | Departure days Mon | Cheapest price $107 |
Operator Greyhound | Departure Time 05:20PM | Arrival Time 10:20PM | Duration 5h00 | Departure days Mon | Cheapest price $49 |
Operator Infobus | Departure Time 05:51PM | Arrival Time 08:16PM | Duration 2h25 | Departure days Mon | Cheapest price $107 |
Operator Greyhound | Departure Time 07:35PM | Arrival Time 10:20PM | Duration 2h45 | Departure days Mon | Cheapest price $42 |
Operator Infobus | Departure Time 07:51PM | Arrival Time 10:16PM | Duration 2h25 | Departure days Mon | Cheapest price $107 |
Operator Infobus | Departure Time 08:20PM | Arrival Time 11:50PM | Duration 3h30 | Departure days Mon | Cheapest price $75 |
Compare prices and tickets La Mesa, CA to Los Angeles, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 06
Apr 07
Apr 08
Apr 09
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Apr 11
Apr 12
Why should you book La Mesa, CA to Los Angeles, CA buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from La Mesa, CA to Los Angeles, CA.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from La Mesa, CA to Los Angeles, CA.
Journey information
Overview: Bus from La Mesa, CA to Los Angeles, CA
Buses from La Mesa, CA to Los Angeles, CA run on average 39 times per day, taking around 3h 44m. Cheap bus tickets for this journey start at $24 (€19) if you book in advance.
There are 37 buses per day. The earliest bus runs at 00:05, the last at 23:30. The fastest bus covers the 113 miles (182 km) distance in 3h 20m.
Distance 113 miles (182 km) |
Average bus duration 3h 44m |
Cheapest ticket price $24 (€19) |
Buses per day 39 |
Direct buses 37 |
Fastest bus 3h 20m |
First bus 12:05 AM |
Last bus 11:30 PM |
Bus providers: FlixBus from La Mesa, CA to Los Angeles, CAYou can travel by bus between La Mesa, CA to Los Angeles, CA with FlixBus for as low as $24 (€19). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from La Mesa, CA to Los Angeles, CA
Find answers to the most common questions about traveling from La Mesa, CA to Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Los Angeles, CA, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Griffith Observatory, an iconic facility offering stunning views of Los Angeles and exhibits on astronomy
- The Getty Center, a renowned art museum with impressive architecture and beautiful gardens
- Santa Monica Pier, a historic landmark featuring an amusement park, aquarium, and scenic ocean views
- Hollywood Walk of Fame, a famous sidewalk celebrating entertainment industry icons with star plaques
- Los Angeles County Museum of Art (LACMA), the largest art museum in the western United States with diverse collections.
- Explore the vibrant Venice Beach Boardwalk, known for its eclectic shops, street performers, and skate park
- Visit the historic El Capitan Theatre for a classic movie experience
- Take a scenic hike in Runyon Canyon Park, offering panoramic views of the city
- Enjoy a live performance at the Walt Disney Concert Hall, known for its stunning architecture and acoustics
- Discover the unique exhibits at the Natural History Museum of Los Angeles County.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from La Mesa, CA to Los Angeles, CA
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