The cheapest and fastest buses from Palermo to Milan
Cheapest price
$118
Average price
$191
Fastest journey
19 h 10 m
Average duration
21 h 48 m
Buses per day
7
Distance
887 km
The best way to find a cheap bus ticket from Palermo to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Milan will cost around $191 if you buy it on the day, but the cheapest tickets can be found for only $118.
Of the 7 buses that leave Palermo for Milan on Mon, Apr 06, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Apr 06 the direct buses cover the 887 km distance in an average of 21 h 48 m but if you time it right, some buses will get you there in just 19 h 10 m .
On Mon, Apr 06 the slowest buses will take 1 d 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
S202 · S1226:00 PM19h10Palermo, Via Tommaso Fazello (Terminal Bus)1:10 PMMilano, San Donato M3$1181One-way1 transfer
S202 · S1226:00 PM19h50Palermo, Via Tommaso Fazello (Terminal Bus)1:50 PMMilano, Autostazione Lampugnano$1181One-way1 transfer
FlixBus · FlixBus · FlixBus3:25 PM29h30Palermo, Via Tommaso Fazello (Terminal Bus)8:55 PMMilano, Milan Linate Airport$1791One-way2 transfers
FlixBus3:25 PM22h20Palermo, Via Tommaso Fazello (Terminal Bus)1:45 PMMilano, Autostazione Lampugnano$1861One-way0 transfers
FlixBus · FlixBus3:25 PM23h10Palermo, Via Tommaso Fazello (Terminal Bus)2:35 PMMilano, San Donato - Settore B (Viale Giuseppe Impastato)$1991One-way1 transfer
S202 · S1226:00 PM19h10Palermo, Via Tommaso Fazello (Terminal Bus)1:10 PMMilano, San Donato M3$1181One-way1 transfer
S202 · S1226:00 PM19h50Palermo, Via Tommaso Fazello (Terminal Bus)1:50 PMMilano, Autostazione Lampugnano$1181One-way1 transfer
FlixBus3:25 PM22h20Palermo, Via Tommaso Fazello (Terminal Bus)1:45 PMMilano, Autostazione Lampugnano$1861One-way0 transfers
FlixBus · FlixBus3:25 PM23h10Palermo, Via Tommaso Fazello (Terminal Bus)2:35 PMMilano, San Donato - Settore B (Viale Giuseppe Impastato)$1991One-way1 transfer
FlixBus · FlixBus9:10 PM24h30Palermo, Via Tommaso Fazello (Terminal Bus)9:40 PMMilano, Autostazione Lampugnano$2701One-way1 transfer
Travel Information
Compare train, bus, flight, and ferry for Palermo to Milan
Omio recommends booking the flight as it is the most popular option from Palermo to Milan among Omio's users. If you are prioritising price take the ferry with prices starting from $74. For those with little time consider booking a flight which can get you there in 2h 4m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a ferry costs an average of $74, and a train costs an average of $73.
Distance: 551 miles (887 km)
Compare bus with
| Bus | Most popular Flight | Train | Ferry |
|---|---|---|---|
$128 Average price | $141 Average price | $158 Average price | $89 Average price Cheapest |
19h 46m Average total duration 19h 16m Onboard + 30m Additional time* | 5h 4m Average total duration Fastest 2h 4m Onboard + 3h 0m Additional time* | 15h 43m Average total duration 15h 13m Onboard + 30m Additional time* | 21h 18m Average total duration 20h 18m Onboard + 1h 0m Additional time* |
0.9 - 2.2kg CO2 emissions | - CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | ![]() Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Palermo to Milan Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:25PM | Arrival Time 01:45PM | Duration 22h20 | Departure days Everyday | Cheapest price $115 |
Operator BlaBlaCar | Departure Time 04:20PM | Arrival Time 10:10AM | Duration 17h50 | Departure days Sun | Cheapest price $125 |
Operator Salemi | Departure Time 06:00PM | Arrival Time 01:10PM | Duration 19h10 | Departure days Mon, Tue, Wed, Sat | Cheapest price $118 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 08:55PM | Duration 23h45 | Departure days Everyday | Cheapest price $74 |
Live departures
Palermo to Milan bus times
The table below shows live departures for Palermo to Milan buses for today, Sunday, April 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 1:25 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 22h20 | 11:45 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 1:25 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 23h10 | 12:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus · FlixBus | 7:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 23h45 | 6:55 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus · FlixBus | 7:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 24h30 | 7:40 PM Milano, Autostazione Lampugnano | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Palermo to Milan by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Palermo to Milan buses with Omio?
Why book with Omio vs Itabus?
- Compare with other providers: On Omio, you can not only buy tickets for Itabus, but also compare tickets for the likes of Autoservizi Salemi, FlixBus or Infobus to find the best option for your trip from Palermo to Milan.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Itabus with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Palermo to Milan.
Why book with Omio over Checkmybus, Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Autoservizi Salemi, FlixBus or Infobus to find the best option for your trip from Palermo to Milan.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus, flight and ferry to find the ideal travel option from Palermo to Milan.
Journey information
Overview: Bus from Palermo to Milan
Buses from Palermo to Milan run on average 6 times per day, taking around 19h 16m. Cheap bus tickets for this journey start at $61 (€50) but you can travel from only $21 (€17) by flight.
There are 1 buses per day. The earliest bus runs at 01:01, the last at 23:05. The fastest bus covers the 551 miles (887 km) distance in 22h 15m.
Distance 551 miles (887 km) |
Average bus duration 19h 16m |
Cheapest ticket price $61 (€50) |
Buses per day 6 |
Direct buses 1 |
Fastest bus 22h 15m |
First bus 1:01 AM |
Last bus 11:05 PM |
Bus providers: Itabus, Autoservizi Salemi, FlixBus, BlaBlaCar, Infobus from Palermo to MilanYou can travel by bus between Palermo to Milan with Itabus, Autoservizi Salemi, FlixBus, BlaBlaCar, Infobus for as low as $21 (€17). When you search for schedules and tickets, Omio will show you the best journey
Itabus
FlixBus
Infobus
Autoservizi Salemi
BlaBlaCar
FAQs: Bus from Palermo to Milan
Find answers to the most common questions about traveling from Palermo to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Duomo di Milano, an iconic Gothic cathedral known for its intricate facade and panoramic rooftop views
- Galleria Vittorio Emanuele II, a historic shopping arcade featuring luxury brands and elegant architecture
- Castello Sforzesco, a Renaissance fortress housing museums and art collections
- Santa Maria delle Grazie, a church famous for housing Leonardo da Vinci's The Last Supper
- Teatro alla Scala, a world-renowned opera house celebrated for its exceptional acoustics and performances.
- Visit the Duomo di Milano, an iconic Gothic cathedral with stunning architecture and panoramic rooftop views
- Explore The Last Supper, Leonardo da Vinci's renowned mural located in the Convent of Santa Maria delle Grazie
- Stroll through Galleria Vittorio Emanuele II, a historic shopping arcade with luxury boutiques and elegant cafes
- Discover Sforza Castle, a grand fortress housing several museums and art collections
- Relax in Sempione Park, a large green space perfect for leisurely walks and picnics near the city center.
- Autoservizi Salemi
- The cancellation policy can vary by ticket class, individual trips, or promotions, so it's best to check the terms during booking.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Autoservizi Salemi
- Two pieces of luggage: one large suitcase for the hold and one smaller backpack for on-board.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Palermo to Milan
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
Most popular bus connections from Palermo
More options for your journey from Palermo to Milan
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