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The cheapest and fastest buses from Prague to Lyon
Showing times and prices for Apr 02
Cheapest price
$150
Average price
$199
Fastest journey
14 h 50 m
Average duration
16 h 7 m
Buses per day
16
Distance
860 km
Cheap tickets
The best way to find a cheap bus ticket from Prague to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Lyon will cost around $199 if you buy it on the day, but the cheapest tickets can be found for only $150.
Fast buses
Of the 16 buses that leave Prague for Lyon on Thu, Apr 02, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Apr 02 the direct buses cover the 860 km distance in an average of 16 h 7 m but if you time it right, some buses will get you there in just 14 h 50 m .
On Thu, Apr 02 the slowest buses will take 17 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus6:40 AM16h35Praha, ÚAN Florenc11:15 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1501One-way0 transfers- FlixBus · FlixBus11:50 PM21h00Prague, Central Train Station8:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1561One-way1 transfer
- FlixBus9:50 PM14h50Praha, Na Knížecí12:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1581One-way0 transfers
- FlixBus9:25 PM15h15Praha, ÚAN Florenc12:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1581One-way0 transfers
- FlixBus · FlixBus3:50 AM19h25Prague, Central Train Station11:15 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1621One-way1 transfer
- FlixBus9:50 PM14h50Praha, Na Knížecí12:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1581One-way0 transfers
- FlixBus9:25 PM15h15Praha, ÚAN Florenc12:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1581One-way0 transfers
- FlixBus6:40 AM16h35Praha, ÚAN Florenc11:15 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1501One-way0 transfers
- FlixBus4:15 PM16h50Prague, Central Train Station9:05 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$2471One-way0 transfers
- FlixBus3:10 PM17h05Praha, ÚAN Florenc8:15 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$2251One-way0 transfers
Travel Information
Compare train, bus, and flight for Prague to Lyon
Omio recommends booking the flight as it is the most popular option from Prague to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $57. For those with little time consider booking a flight which can get you there in 2h 42m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of $57, and a train costs an average of $273.
Distance: 534 miles (860 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$85 Average price Cheapest | $186 Average price | $309 Average price |
17h 2m Average total duration 16h 32m Onboard + 30m Additional time* | 5h 42m Average total duration Fastest 2h 42m Onboard + 3h 0m Additional time* | 14h 30m Average total duration 14h 0m Onboard + 30m Additional time* |
0.9 - 2.1kg CO2 emissions Lowest | 2.6 - 5.2kg CO2 emissions | - CO2 emissions |
Most popular bus company |  Most popular airline |  Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Prague to Lyon Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:30AM | Arrival Time 09:40PM | Duration 19h10 | Departure days Tue, Thu, Sat, Sun | Cheapest price $91 |
Operator FlixBus | Departure Time 03:50AM | Arrival Time 11:15PM | Duration 19h25 | Departure days Everyday | Cheapest price $91 |
Operator FlixBus | Departure Time 04:10AM | Arrival Time 11:15PM | Duration 19h05 | Departure days Everyday | Cheapest price $91 |
Operator FlixBus | Departure Time 06:40AM | Arrival Time 11:15PM | Duration 16h35 | Departure days Everyday | Cheapest price $122 |
Operator FlixBus | Departure Time 07:55AM | Arrival Time 04:35AM | Duration 20h40 | Departure days Mon, Fri, Sat, Sun | Cheapest price $91 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 04:35AM | Duration 19h35 | Departure days Mon, Fri, Sat, Sun | Cheapest price $91 |
Operator FlixBus | Departure Time 09:10AM | Arrival Time 04:45AM | Duration 19h35 | Departure days Everyday | Cheapest price $91 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 08:15AM | Duration 21h20 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $101 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 08:15AM | Duration 19h20 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $92 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 08:15AM | Duration 19h10 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $92 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 08:15AM | Duration 17h45 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $115 |
Operator FlixBus | Departure Time 03:10PM | Arrival Time 08:15AM | Duration 17h05 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $115 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 09:05AM | Duration 17h05 | Departure days Everyday | Cheapest price $112 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 09:05AM | Duration 16h50 | Departure days Everyday | Cheapest price $112 |
Operator BlaBlaCar Bus | Departure Time 07:00PM | Arrival Time 06:50PM | Duration 23h50 | Departure days Thu, Sun | Cheapest price $102 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 12:40PM | Duration 15h15 | Departure days Everyday | Cheapest price $115 |
Operator FlixBus | Departure Time 09:50PM | Arrival Time 12:40PM | Duration 14h50 | Departure days Everyday | Cheapest price $115 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 08:50PM | Duration 21h00 | Departure days Everyday | Cheapest price $100 |
Live departures
Prague to Lyon bus times
The table below shows live departures for Prague to Lyon buses for today, Wednesday, April 1. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 7:10 AM Praha, Na Knížecí | 19h35 | 2:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| FlixBus | 2:00 PM Praha, ÚAN Florenc | 17h05 | 7:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| FlixBus | 2:15 PM Prague, Central Train Station | 16h50 | 7:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| FlixBus | 7:25 PM Praha, ÚAN Florenc | 15h15 | 10:40 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| FlixBus | 7:50 PM Praha, Na Knížecí | 14h50 | 10:40 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| FlixBus · FlixBus | 9:50 PM Prague, Central Train Station | 21h00 | 6:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| Thursday, April 2 | |||||
| FlixBus · FlixBus · FlixBus | 12:30 AM Prague, Central Train Station | 19h10 | 7:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 2 transfers | |
| FlixBus · FlixBus | 1:50 AM Prague, Central Train Station | 19h25 | 9:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| FlixBus · FlixBus | 2:10 AM Praha, Na Knížecí | 19h05 | 9:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| FlixBus | 4:40 AM Praha, ÚAN Florenc | 16h35 | 9:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Prague to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Prague to Lyon buses with Omio?
FlixBus as well as BlaBlaCar Bus offer buses services from Prague to Lyon.
Omio is an official ticket reseller for all your travel options from Prague to Lyon.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Prague to Lyon.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Prague to Lyon.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Prague to Lyon.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Prague to Lyon.
Journey information
Overview: Bus from Prague to Lyon
Czechia
France
Buses from Prague to Lyon run on average 12 times per day, taking around 16h 32m. Cheap bus tickets for this journey start at $57 (€46) but you can travel from only $52 (€42) by flight.
There are 6 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 534 miles (860 km) distance in 14h 35m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $52 (€42)
Distance 534 miles (860 km) |
Average bus duration 16h 32m |
Cheapest ticket price $57 (€46) |
Buses per day 12 |
Direct buses 6 |
Fastest bus 14h 35m |
First bus 12:10 AM |
Last bus 11:55 PM |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $52 (€42)
Bus providers: FlixBus, BlaBlaCar Bus from Prague to LyonYou can travel by bus between Prague to Lyon with FlixBus, BlaBlaCar Bus for as low as $52 (€42). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
14h 35m
Cheapest Price
$57 (€46)
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
BlaBlaCar Bus
About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average Duration
16h 50m
Cheapest Price
$59 (€48)
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.
FAQs: Bus from Prague to Lyon
Find answers to the most common questions about traveling from Prague to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Prague to Lyon can start from as little as $57 (€46) when you book in advance. The average bus ticket price for Prague to Lyon is $85 (€69) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Prague to Lyon is 14h 35m to travel the 534 miles (860 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Prague to Lyon leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Prague to Lyon leaves at 11:55 PM.
Yes, there are 6 direct buses a day from Prague to Lyon with FlixBus, BlaBlaCar Bus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Prague to Lyon, you can count on FlixBus, BlaBlaCar Bus for the best way to get you to Lyon. You can also check all possible bus companies who offer a service between Prague and Lyon and compare the amenities they offer before buying a bus ticket.
When departing from Prague , you have various bus station options to start your journey from including Praha, ÚAN Florenc, Prague, Central Train Station, Praha, Na Knížecí, Praha, Zličín, Praha, Černý Most, Praha, M. Horákové (Hradčanská), Praha, Letiště Václava Havla, Praha, Roztyly . When arriving in Lyon , you can end your journey in bus stations like Lyon, Perrache Bus Station, Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland), Lyon, St Exupéry Aéroport, Givors, Plaza Jean Berry, Lyon, Gare Perrache .Passengers board the bus most frequently from Praha, ÚAN Florenc, which is located around 1 away from the city centre, and they get off the bus at Lyon, Perrache Bus Station, located 1 away from the city centre.
A trip to Lyon from Prague is worth doing but not as a day trip with a journey time of 14h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Prague to Lyon is April.
It's helpful to compare your options as there are 3 ways to travel between Prague and Lyon including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Prague to Lyon:
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Prague to Lyon for bus company FlixBus, BlaBlaCar Bus.
Some of the most interesting sights to explore in Lyon are:
- Basilica of Notre-Dame de Fourvière, a stunning 19th-century basilica offering panoramic views of the city
- Vieux Lyon, a UNESCO World Heritage site known for its Renaissance architecture and narrow cobblestone streets
- Parc de la Tête d'Or, a large urban park featuring a zoo, botanical garden, and lake
- Musée des Confluences, a modern science and anthropology museum with innovative exhibits
- Place Bellecour, one of Europe's largest open squares, ideal for shopping and dining.
The best things to do in Lyon include:
- Les Halles de Lyon Paul Bocuse, a renowned indoor market offering gourmet food and local specialties
- Take a river cruise on the Rhône and Saône for a unique view of the city
- Explore the traboules, secret passageways in Vieux Lyon
- Attend a performance at the Opéra de Lyon, known for its diverse program
- Visit the Institut Lumière, dedicated to the history of cinema.
Whether you can cancel your bus ticket from Prague to Lyon depends on the bus companies:
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, BlaBlaCar Bus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Prague to Lyon.
Yes, the following luggage options are included when booking a bus ticket from Prague to Lyon:
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Prague to Lyon:
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Prague to Lyon. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Prague to Lyon with the following bus company: FlixBus, BlaBlaCar Bus
Yes, there are USB plugs on board the bus from Prague to Lyon with the following bus company: FlixBus, BlaBlaCar Bus.
Yes, there is Wifi on board the bus from Prague to Lyon with the following bus company: FlixBus, BlaBlaCar Bus.
Since both Prague and Lyon are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Prague to Lyon among Omio's users.
France uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most transactions, especially in cities and larger establishments, but carrying some cash is advisable for small vendors, markets, and rural areas where card acceptance may be limited.
In Lyon, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, popular tourist spots, and markets. Common scams include distraction techniques and fake charity collectors. It's advisable to keep valuables secure and be wary of overly friendly strangers offering unsolicited help. Avoid unlicensed taxi services to prevent overcharging. Staying alert in busy zones ensures a safer visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Prague to Lyon
Prague
Lyon
The major bus station for departures in Prague is Praha, ÚAN Florenc. Find all the information you need to know about services, amenities and connections at Praha, ÚAN Florenc for your trip from Prague to Lyon.
Amenities at bus station
Wifi
Parking
Dining
ATM
Taxis
Accessibility
WC
Ticket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
1 km
Car connection
KřižíkovaWifi
- Free Wi-Fi
Dining
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, ÚAN Florenc
- Bus: 133, 135, 175, 207 Metro: B, C
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 00:00-23:59
Distance to city center
1 kmCar connection
WilsonovaWifi
- Free Wi-Fi
Dining
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, Hlavní Nádraží
- Bus: 135, 175, 207 Metro: C Train: All major s
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCinformation
Distance to city center
2 kmCar connection
OstrovskéhoWifi
- Free Wi-Fi
Dining
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, Na Knížecí
- Bus: 137, 176, 191 Metro: B
The major bus station for arrivals in Lyon is Lyon, Gare Routière de Perrache. Find all the information you need to know about services, amenities and connections at Lyon, Gare Routière de Perrache for your trip to Lyon from Prague.
Lyon, Gare Routière de Perrache
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
1 kmCar connection
Cours de VerdunWifi
- Free Wi-Fi
Dining
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Lyon, Gare Routière de Perrache
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
information
Lyon, St Exupéry Aéroport
information
More options for your journey from Prague to Lyon
Here are some other resources that might have the information you need
Most popular buses to and from Lyon and Prague
Most popular bus connections to Lyon
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