The cheapest and fastest buses from Rome to Frankfurt am Main
Cheapest price
$125
Average price
$158
Fastest journey
19 h 35 m
Average duration
19 h 54 m
Buses per day
28
Distance
960 km
The best way to find a cheap bus ticket from Rome to Frankfurt am Main is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Frankfurt am Main will cost around $158 if you buy it on the day, but the cheapest tickets can be found for only $125.
Of the 28 buses that leave Rome for Frankfurt am Main on Thu, Apr 02, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Apr 02 the direct buses cover the 960 km distance in an average of 19 h 54 m but if you time it right, some buses will get you there in just 19 h 35 m .
On Thu, Apr 02 the slowest buses will take 20 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus+
FlixTrain12:10PM23h19Roma, Autostazione Tiburtina11:29AMFrankfurt South station$1251One-way2 transfers
FlixBus · FlixBus05:00PM22h00Roma, Autostazione Tiburtina03:00PMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$1321One-way1 transfer
FlixBus04:35PM20h55Roma, Autostazione Tiburtina01:30PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$1321One-way0 transfers
FlixBus · FlixBus10:10AM19h50Roma, Autostazione Tiburtina06:00AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$1351One-way1 transfer
FlixBus · FlixBus+
FlixTrain05:00PM24h10Roma, Autostazione Tiburtina05:10PMFrankfurt South station$1361One-way2 transfers
FlixBus · FlixBus10:40AM19h35Roma, Autostazione Tiburtina06:15AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$1371One-way1 transfer
FlixBus · FlixBus · FlixBus05:25PM19h40Roma, Autostazione (Metro Anagnina)01:05PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$1751One-way2 transfers
FlixBus · FlixBus10:10AM19h50Roma, Autostazione Tiburtina06:00AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$1351One-way1 transfer
FlixBus · FlixBus09:25AM20h05Roma, Autostazione Tiburtina05:30AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$2381One-way1 transfer
FlixBus · FlixBus09:45PM20h20Roma, Autostazione Tiburtina06:05PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$1741One-way1 transfer
Travel Information
Compare train, bus, and flight for Rome to Frankfurt am Main
Omio recommends booking the flight as it is the most popular option from Rome to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from $64. For those with little time consider booking a flight which can get you there in 2h 52m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.0 - 2.4kg. The ticket price range depends on the travel mode: a bus costs an average of $64, and a train costs an average of $312.
Distance: 596 miles (960 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$110 Average price Cheapest | $142 Average price | $312 Average price |
24h 5m Average total duration 23h 35m Onboard + 30m Additional time* | 5h 52m Average total duration Fastest 2h 52m Onboard + 3h 0m Additional time* | 12h 12m Average total duration 11h 42m Onboard + 30m Additional time* |
1.0 - 2.4kg CO2 emissions Lowest | 2.9 - 5.8kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Rome to Frankfurt am Main Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:15AM | Arrival Time 10:45PM | Duration 22h30 | Departure days Mon, Tue, Thu, Fri, Sat | Cheapest price $154 |
Operator FlixBus | Departure Time 09:25AM | Arrival Time 05:30AM | Duration 20h05 | Departure days Everyday | Cheapest price $151 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 07:45AM | Duration 22h15 | Departure days Everyday | Cheapest price $135 |
Operator FlixBus | Departure Time 10:10AM | Arrival Time 06:00AM | Duration 19h50 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $114 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 06:15AM | Duration 19h35 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $123 |
Operator FlixBus | Departure Time 11:50AM | Arrival Time 09:45AM | Duration 21h55 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $126 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 01:26PM | Duration 25h16 | Departure days Everyday | Cheapest price $115 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 09:45AM | Duration 21h25 | Departure days Everyday | Cheapest price $141 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 09:45AM | Duration 21h00 | Departure days Sun | Cheapest price $177 |
Operator RegioJet a.s. | Departure Time 01:00PM | Arrival Time 05:25AM | Duration 40h25 | Departure days Sun | Cheapest price $184 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 01:26PM | Duration 24h21 | Departure days Everyday | Cheapest price $129 |
Operator FlixBus | Departure Time 03:15PM | Arrival Time 06:45PM | Duration 27h30 | Departure days Fri | Cheapest price $199 |
Operator BlaBlaCar Bus | Departure Time 03:20PM | Arrival Time 11:55PM | Duration 32h35 | Departure days Thu, Sat | Cheapest price $162 |
Operator FlixBus | Departure Time 03:45PM | Arrival Time 03:26PM | Duration 23h41 | Departure days Sun | Cheapest price $200 |
Operator FlixBus | Departure Time 04:35PM | Arrival Time 01:30PM | Duration 20h55 | Departure days Everyday | Cheapest price $132 |
Operator FlixBus | Departure Time 05:00PM | Arrival Time 03:00PM | Duration 22h00 | Departure days Everyday | Cheapest price $132 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 01:05PM | Duration 19h40 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $132 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 03:55PM | Duration 19h55 | Departure days Everyday | Cheapest price $133 |
Operator FlixBus | Departure Time 09:45PM | Arrival Time 06:05PM | Duration 20h20 | Departure days Everyday | Cheapest price $126 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 08:30PM | Duration 21h35 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $132 |
Operator Marino Autolinee | Departure Time 11:00PM | Arrival Time 07:15PM | Duration 20h15 | Departure days Wed | Cheapest price $185 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 12:15AM | Duration 24h40 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $136 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 10:45PM | Duration 22h55 | Departure days Everyday | Cheapest price $144 |
Live departures
Rome to Frankfurt am Main bus times
The table below shows live departures for Rome to Frankfurt am Main buses for today, Wednesday, April 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 11:05 AM Roma, Autostazione (Metro Anagnina) | 23h20 | 10:25 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:05 AM Roma, Autostazione (Metro Anagnina) | 22h25 | 9:30 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 2 transfers | |
FlixBus · FlixBus+ FlixTrain | 11:05 AM Roma, Autostazione (Metro Anagnina) | 24h21 | 11:26 AM Frankfurt South station | 2 transfers | |
FlixBus | 2:35 PM Roma, Autostazione Tiburtina | 20h55 | 11:30 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus · FlixBus | 3:00 PM Roma, Autostazione Tiburtina | 22h00 | 1:00 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:25 PM Roma, Autostazione (Metro Anagnina) | 21h35 | 1:00 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:25 PM Roma, Autostazione (Metro Anagnina) | 19h40 | 11:05 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 2 transfers | |
FlixBus · FlixBus+ FlixTrain | 6:00 PM Roma, Autostazione Tiburtina | 19h55 | 1:55 PM Frankfurt South station | 2 transfers | |
FlixBus · FlixBus | 6:00 PM Roma, Autostazione Tiburtina | 21h35 | 3:35 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 6:00 PM Roma, Autostazione Tiburtina | 22h00 | 4:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 7:45 PM Roma, Autostazione Tiburtina | 21h00 | 4:45 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 7:45 PM Roma, Autostazione Tiburtina | 20h20 | 4:05 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 8:55 PM Roma, Autostazione Tiburtina | 21h35 | 6:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
054 · 253* | 9:00 PM Roma, Autostazione Tiburtina | 20h15 | 5:15 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 9:35 PM Roma, Autostazione (Metro Anagnina) | 23h10 | 8:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:35 PM Roma, Autostazione (Metro Anagnina) | 24h40 | 10:15 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 2 transfers | |
FlixBus · FlixBus | 9:50 PM Roma, Autostazione Tiburtina | 22h55 | 8:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 10:15 PM Roma, Autostazione Tiburtina | 22h30 | 8:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
| Thursday, April 2 | |||||
FlixBus · FlixBus | 7:25 AM Roma, Autostazione Tiburtina | 20h05 | 3:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 7:25 AM Roma, Autostazione Tiburtina | 20h25 | 3:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 22h15 | 5:45 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus+ FlixTrain | 7:30 AM Roma, Autostazione Tiburtina | 23h55 | 7:25 AM Frankfurt South station | 2 transfers | |
FlixBus · FlixBus | 8:10 AM Roma, Autostazione Tiburtina | 19h50 | 4:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 8:40 AM Roma, Autostazione Tiburtina | 19h35 | 4:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 9:50 AM Roma, Autostazione (Metro Anagnina) | 21h55 | 7:45 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 10:10 AM Roma, Autostazione Tiburtina | 23h20 | 9:30 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus+ FlixTrain | 10:10 AM Roma, Autostazione Tiburtina | 23h19 | 9:29 AM Frankfurt South station | 2 transfers | |
FlixBus · FlixBus | 10:20 AM Roma, Autostazione Tiburtina | 21h25 | 7:45 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Frankfurt am Main by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 01
Apr 02
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Apr 04
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Apr 06
Apr 07
Apr 08
Apr 09
Apr 10
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Apr 15
Apr 16
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Apr 21
Why should you book Rome to Frankfurt am Main buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus or Marino Autolinee to find the best option for your trip from Rome to Frankfurt am Main.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome to Frankfurt am Main.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus or Marino Autolinee to find the best option for your trip from Rome to Frankfurt am Main.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome to Frankfurt am Main.
Journey information
Overview: Bus from Rome to Frankfurt am Main
Buses from Rome to Frankfurt am Main run on average 22 times per day, taking around 23h 35m. Cheap bus tickets for this journey start at $64 (€52) but you can travel from only $27 (€22) by flight.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 596 miles (960 km) distance in 19h 40m.
Distance 596 miles (960 km) |
Average bus duration 23h 35m |
Cheapest ticket price $64 (€52) |
Buses per day 22 |
Direct buses 1 |
Fastest bus 19h 40m |
First bus 00:05 |
Last bus 23:55 |
Bus providers: FlixBus, BlaBlaCar Bus, Marino Autolinee from Rome to Frankfurt am MainYou can travel by bus between Rome to Frankfurt am Main with FlixBus, BlaBlaCar Bus, Marino Autolinee for as low as $27 (€22). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Marino Autolinee
BlaBlaCar Bus
FAQs: Bus from Rome to Frankfurt am Main
Find answers to the most common questions about traveling from Rome to Frankfurt am Main by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Römer, a historic city hall with medieval architecture located in the heart of Frankfurt's old town
- Städel Museum, an art museum featuring a vast collection of European artworks from the Middle Ages to the present
- Palmengarten, a large botanical garden showcasing diverse plant species in themed greenhouses and outdoor areas
- Goethe House, the birthplace of the famous writer Johann Wolfgang von Goethe, now a museum dedicated to his life and works
- Frankfurt Cathedral, a Gothic-style church with a rich history and stunning architecture.
- Main Tower, a skyscraper with an observation deck providing panoramic views of the city
- Explore the vibrant Kleinmarkthalle, an indoor market offering a variety of local and international foods
- Visit the Senckenberg Natural History Museum, home to an extensive collection of dinosaur fossils and natural exhibits
- Take a leisurely walk along the River Main and enjoy the scenic views
- Experience the lively atmosphere of the Zeil, Frankfurt's premier shopping street.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Rome to Frankfurt am Main
- 00:00-23:59
- Free Wi-Fi
- McDonald's (in the station)
- Hausmann's (in the station).
- Available outside the terminal at designated taxi stands.
- Elevators, ramps, assistance
- Available in the station.
- Bus: 61, 62, 77 Train: S8, S9
More options for your journey from Rome to Frankfurt am Main
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