2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Rome to Prague
Showing times and prices for Apr 04
Cheapest price
$140
Average price
$162
Fastest journey
19 h 55 m
Average duration
20 h 15 m
Buses per day
44
Distance
923 km
Cheap tickets
The best way to find a cheap bus ticket from Rome to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Prague will cost around $162 if you buy it on the day, but the cheapest tickets can be found for only $140.
Fast buses
Of the 44 buses that leave Rome for Prague on Sat, Apr 04, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Apr 04 the direct buses cover the 923 km distance in an average of 20 h 15 m but if you time it right, some buses will get you there in just 19 h 55 m .
On Sat, Apr 04 the slowest buses will take 20 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus · FlixBus9:00 PM23h20Roma, Autostazione Tiburtina8:20 PMPraha, Na Knížecí$1401One-way2 transfers- FlixBus · FlixBus9:00 PM20h30Roma, Autostazione Tiburtina5:30 PMPrague, Central Train Station$1411One-way1 transfer
- FlixBus · FlixBus9:00 PM20h45Roma, Autostazione Tiburtina5:45 PMPraha, ÚAN Florenc$1411One-way1 transfer
- FlixBus · FlixBus1:05 PM20h20Roma, Autostazione (Metro Anagnina)9:25 AMPraha, ÚAN Florenc$1411One-way1 transfer
- FlixBus · FlixBus · FlixBus9:00 PM26h55Roma, Autostazione Tiburtina11:55 PMPrague, Central Train Station$1411One-way2 transfers
- FlixBus · FlixBus · FlixBus5:25 PM19h55Roma, Autostazione (Metro Anagnina)1:20 PMPrague, Central Train Station$1551One-way2 transfers
- FlixBus · FlixBus · FlixBus5:25 PM20h05Roma, Autostazione (Metro Anagnina)1:30 PMPraha, ÚAN Florenc$1551One-way2 transfers
- FlixBus · FlixBus1:05 PM20h20Roma, Autostazione (Metro Anagnina)9:25 AMPraha, ÚAN Florenc$1411One-way1 transfer
- FlixBus · FlixBus10:55 PM20h25Roma, Autostazione Tiburtina7:20 PMPrague, Central Train Station$1611One-way1 transfer
- FlixBus · FlixBus9:00 PM20h30Roma, Autostazione Tiburtina5:30 PMPrague, Central Train Station$1411One-way1 transfer
Travel Information
Compare train, bus, and flight for Rome to Prague
Omio recommends booking the flight as it is the most popular option from Rome to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $68. For those with little time consider booking a flight which can get you there in 2h 49m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a bus costs an average of $68, and a train costs an average of $231.
Distance: 573 miles (923 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$116 Average price Cheapest | $140 Average price | $259 Average price |
20h 15m Average total duration 19h 45m Onboard + 30m Additional time* | 5h 49m Average total duration Fastest 2h 49m Onboard + 3h 0m Additional time* | 18h 2m Average total duration 17h 32m Onboard + 30m Additional time* |
0.9 - 2.3kg CO2 emissions Lowest | 2.8 - 5.5kg CO2 emissions | - CO2 emissions |
Most popular bus company |  Most popular airline |  Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Rome to Prague Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:20AM | Arrival Time 03:15AM | Duration 25h55 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $104 |
Operator FlixBus | Departure Time 01:40AM | Arrival Time 05:45AM | Duration 28h05 | Departure days Sat, Sun | Cheapest price $172 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 05:45AM | Duration 22h15 | Departure days Mon, Tue, Thu, Fri | Cheapest price $107 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 08:55AM | Duration 23h25 | Departure days Everyday | Cheapest price $95 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 11:30AM | Duration 24h50 | Departure days Everyday | Cheapest price $138 |
Operator FlixBus | Departure Time 11:10AM | Arrival Time 10:45AM | Duration 23h35 | Departure days Tue, Wed | Cheapest price $126 |
Operator FlixBus | Departure Time 11:50AM | Arrival Time 11:45AM | Duration 23h55 | Departure days Everyday | Cheapest price $107 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 01:20PM | Duration 25h00 | Departure days Everyday | Cheapest price $100 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 01:45PM | Duration 25h00 | Departure days Mon, Thu, Fri, Sun | Cheapest price $100 |
Operator RegioJet a.s. | Departure Time 01:00PM | Arrival Time 09:10AM | Duration 20h10 | Departure days Sun | Cheapest price $98 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 01:30PM | Duration 24h25 | Departure days Everyday | Cheapest price $95 |
Operator FlixBus | Departure Time 03:15PM | Arrival Time 08:55PM | Duration 29h40 | Departure days Tue | Cheapest price $179 |
Operator FlixBus | Departure Time 05:00PM | Arrival Time 07:50PM | Duration 26h50 | Departure days Everyday | Cheapest price $122 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 01:55PM | Duration 20h50 | Departure days Everyday | Cheapest price $97 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 01:20PM | Duration 19h55 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $123 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 09:30PM | Duration 27h15 | Departure days Sat, Sun | Cheapest price $174 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 08:20PM | Duration 23h20 | Departure days Everyday | Cheapest price $113 |
Operator FlixBus | Departure Time 09:20PM | Arrival Time 08:15PM | Duration 22h55 | Departure days Mon, Tue | Cheapest price $153 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 10:55PM | Duration 24h00 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $123 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 10:35PM | Duration 23h30 | Departure days Everyday | Cheapest price $155 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 03:15AM | Duration 27h40 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $120 |
Live departures
Rome to Prague bus times
The table below shows live departures for Rome to Prague buses for today, Friday, April 3. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus · FlixBus | 10:45 AM Roma, Autostazione (Metro Anagnina) | 25h00 | 11:45 AM Praha, Černý Most | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 10:45 AM Roma, Autostazione (Metro Anagnina) | 24h35 | 11:20 AM Praha, Roztyly | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 11:05 AM Roma, Autostazione (Metro Anagnina) | 27h05 | 2:10 PM Praha, Černý Most | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 11:05 AM Roma, Autostazione (Metro Anagnina) | 24h25 | 11:30 AM Praha, Roztyly | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 11:05 AM Roma, Autostazione (Metro Anagnina) | 28h30 | 3:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
| FlixBus · FlixBus | 11:05 AM Roma, Autostazione (Metro Anagnina) | 20h20 | 7:25 AM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 11:05 AM Roma, Autostazione (Metro Anagnina) | 21h30 | 8:35 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus | 3:00 PM Roma, Autostazione Tiburtina | 27h00 | 6:00 PM Prague, Central Train Station | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 3:05 PM Roma, Autostazione Tiburtina | 25h25 | 4:30 PM Praha, Zličín | 2 transfers | |
| FlixBus | 3:05 PM Roma, Autostazione Tiburtina | 20h50 | 11:55 AM Praha, ÚAN Florenc | 0 transfersDirect | |
| FlixBus | 3:05 PM Roma, Autostazione Tiburtina | 20h40 | 11:45 AM Prague, Central Train Station | 0 transfersDirect | |
| FlixBus · FlixBus · FlixBus | 3:05 PM Roma, Autostazione Tiburtina | 26h05 | 5:10 PM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 3:05 PM Roma, Autostazione Tiburtina | 23h05 | 2:10 PM Praha, Černý Most | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 3:05 PM Roma, Autostazione Tiburtina | 23h25 | 2:30 PM Praha, Roztyly | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 3:05 PM Roma, Autostazione Tiburtina | 24h30 | 3:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 3:25 PM Roma, Autostazione (Metro Anagnina) | 24h05 | 3:30 PM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 3:25 PM Roma, Autostazione (Metro Anagnina) | 28h05 | 7:30 PM Praha, Černý Most | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 3:25 PM Roma, Autostazione (Metro Anagnina) | 26h55 | 6:20 PM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 3:25 PM Roma, Autostazione (Metro Anagnina) | 24h20 | 3:45 PM Praha, ÚAN Florenc | 2 transfers | |
| FlixBus · FlixBus | 7:00 PM Roma, Autostazione Tiburtina | 20h30 | 3:30 PM Prague, Central Train Station | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 7:00 PM Roma, Autostazione Tiburtina | 23h20 | 6:20 PM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus | 7:00 PM Roma, Autostazione Tiburtina | 20h45 | 3:45 PM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 7:00 PM Roma, Autostazione Tiburtina | 26h55 | 9:55 PM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus | 8:55 PM Roma, Autostazione Tiburtina | 20h35 | 5:30 PM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus | 8:55 PM Roma, Autostazione Tiburtina | 20h25 | 5:20 PM Prague, Central Train Station | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 8:55 PM Roma, Autostazione Tiburtina | 27h55 | 12:50 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 8:55 PM Roma, Autostazione Tiburtina | 24h00 | 8:55 PM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 9:05 PM Roma, Autostazione Tiburtina | 23h30 | 8:35 PM Praha, Roztyly | 2 transfers | |
| FlixBus · FlixBus | 9:05 PM Roma, Autostazione Tiburtina | 22h25 | 7:30 PM Praha, Černý Most | 1 transfer | |
| FlixBus · FlixBus | 9:05 PM Roma, Autostazione Tiburtina | 21h50 | 6:55 PM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 9:35 PM Roma, Autostazione (Metro Anagnina) | 27h40 | 1:15 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 11:20 PM Roma, Autostazione Tiburtina | 25h55 | 1:15 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus | 11:40 PM Roma, Autostazione Tiburtina | 28h05 | 3:45 AM Praha, ÚAN Florenc | 1 transfer | |
| Saturday, April 4 | |||||
| FlixBus · FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 21h30 | 5:00 AM Prague, Central Train Station | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 23h25 | 6:55 AM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 22h00 | 5:30 AM Praha, M. Horákové (Hradčanská) | 2 transfers | |
| FlixBus · FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 21h40 | 5:10 AM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 26h00 | 9:30 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus | 8:40 AM Roma, Autostazione Tiburtina | 23h55 | 8:35 AM Prague, Central Train Station | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 8:40 AM Roma, Autostazione Tiburtina | 24h50 | 9:30 AM Praha, Zličín | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 9:50 AM Roma, Autostazione (Metro Anagnina) | 23h55 | 9:45 AM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus | 10:20 AM Roma, Autostazione Tiburtina | 21h05 | 7:25 AM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 10:20 AM Roma, Autostazione Tiburtina | 25h25 | 11:45 AM Praha, Černý Most | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 10:20 AM Roma, Autostazione Tiburtina | 23h50 | 10:10 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 10:20 AM Roma, Autostazione Tiburtina | 23h25 | 9:45 AM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 10:20 AM Roma, Autostazione Tiburtina | 25h00 | 11:20 AM Praha, Roztyly | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Fri
Apr 03
Apr 03
Sat
Apr 04
Apr 04
Sun
Apr 05
Apr 05
Mon
Apr 06
Apr 06
Tue
Apr 07
Apr 07
Wed
Apr 08
Apr 08
Thu
Apr 09
Apr 09
Fri
Apr 10
Apr 10
Sat
Apr 11
Apr 11
Sun
Apr 12
Apr 12
Mon
Apr 13
Apr 13
Tue
Apr 14
Apr 14
Wed
Apr 15
Apr 15
Thu
Apr 16
Apr 16
Fri
Apr 17
Apr 17
Sat
Apr 18
Apr 18
Sun
Apr 19
Apr 19
Mon
Apr 20
Apr 20
Tue
Apr 21
Apr 21
Wed
Apr 22
Apr 22
Thu
Apr 23
Apr 23
Why should you book Rome to Prague buses with Omio?
FlixBus operates all buses services from Rome to Prague.
Omio is an official ticket reseller for all your travel options from Rome to Prague.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome to Prague.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome to Prague.
Journey information
Overview: Bus from Rome to Prague
Italy
Czechia
Buses from Rome to Prague run on average 37 times per day, taking around 19h 45m. Cheap bus tickets for this journey start at $68 (€55) but you can travel from only $25 (€20) by flight.
There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 573 miles (923 km) distance in 20h 10m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $25 (€20)
Distance 573 miles (923 km) |
Average bus duration 19h 45m |
Cheapest ticket price $68 (€55) |
Buses per day 37 |
Direct buses 2 |
Fastest bus 20h 10m |
First bus 12:10 AM |
Last bus 11:55 PM |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $25 (€20)
Bus providers: FlixBus from Rome to PragueYou can travel by bus between Rome to Prague with FlixBus for as low as $25 (€20). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
20h 20m
Cheapest Price
$68 (€55)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
FAQs: Bus from Rome to Prague
Find answers to the most common questions about traveling from Rome to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Rome to Prague can start from as little as $68 (€55) when you book in advance. The average bus ticket price for Rome to Prague is $116 (€94) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Rome to Prague is 20h 10m to travel the 573 miles (923 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Rome to Prague leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Rome to Prague leaves at 11:55 PM.
Yes, there are 2 direct buses a day from Rome to Prague with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Rome to Prague, you can count on FlixBus for the best way to get you to Prague. You can also check all possible bus companies who offer a service between Rome and Prague and compare the amenities they offer before buying a bus ticket.
A trip to Prague from Rome is worth doing but not as a day trip with a journey time of 20h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Rome to Prague is May.
It's helpful to compare your options as there are 3 ways to travel between Rome and Prague including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Rome to Prague:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Rome to Prague for bus company FlixBus.
Some of the most interesting sights to explore in Prague are:
- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
The best things to do in Prague include:
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
Whether you can cancel your bus ticket from Rome to Prague depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Rome to Prague.
Yes, the following luggage options are included when booking a bus ticket from Rome to Prague:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Rome to Prague:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Rome to Prague. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Rome to Prague with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Rome to Prague with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Rome to Prague with the following bus company: FlixBus.
Since both Rome and Prague are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Rome to Prague among Omio's users.
The currency used in Czechia is the Czech koruna (CZK). While many places accept card payments, cash is still widely used, especially in smaller shops and markets, so travelers should carry some cash but can also use cards conveniently in most urban areas.
In Prague, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, Old Town Square, and major tourist sites. Common scams include overpriced taxi rides without meters, street vendors selling fake tickets or souvenirs, and distraction techniques used by thieves. It's advisable to use official taxis or ride-hailing apps, keep valuables secure, and be wary of strangers offering unsolicited help.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Rome to Prague
Rome
Prague
The major bus station for departures in Rome is Roma, Autostazione Tiburtina. Find all the information you need to know about services, amenities and connections at Roma, Autostazione Tiburtina for your trip from Rome to Prague.
Roma, Autostazione Tiburtina
information
Roma, Autostazione (Metro Anagnina)
information
Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine"
information
The major bus station for arrivals in Prague is Praha, Hlavní Nádraží. Find all the information you need to know about services, amenities and connections at Praha, Hlavní Nádraží for your trip to Prague from Rome.
Amenities at bus station
Wifi
Parking
Dining
ATM
Taxis
Accessibility
WC
Ticket Officeinformation
Ticket Office Hours
- 00:00-23:59
Distance to city center
1 km
Car connection
WilsonovaWifi
- Free Wi-Fi
Dining
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, Hlavní Nádraží
- Bus: 135, 175, 207 Metro: C Train: All major s
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
1 kmCar connection
KřižíkovaWifi
- Free Wi-Fi
Dining
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, ÚAN Florenc
- Bus: 133, 135, 175, 207 Metro: B, C
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCinformation
Distance to city center
2 kmCar connection
OstrovskéhoWifi
- Free Wi-Fi
Dining
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, Na Knížecí
- Bus: 137, 176, 191 Metro: B
More options for your journey from Rome to Prague
Here are some other resources that might have the information you need
Most popular buses to and from Prague and Rome
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
