The cheapest and fastest buses from San Antonio, TX to Indianapolis, IN
Cheapest price
$181
Average price
$234
Fastest journey
1 d 3 h
Average duration
1 d 9 h 40 m
Buses per day
2
Distance
1609 km
The best way to find a cheap bus ticket from San Antonio, TX to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Indianapolis, IN will cost around $234 if you buy it on the day, but the cheapest tickets can be found for only $181.
Of the 2 buses that leave San Antonio, TX for Indianapolis, IN on Thu, Apr 02, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Apr 02 the direct buses cover the 1609 km distance in an average of 1 d 9 h 40 m but if you time it right, some buses will get you there in just 1 d 3 h .
On Thu, Apr 02 the slowest buses will take 1 d 16 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
6:35 PM27h00San Antonio, TX9:35 PMIndianapolis, IN$1811One-way0 transfers
3:15 AM40h20San Antonio, TX7:35 PMIndianapolis, IN$2861One-way0 transfers
6:35 PM27h00San Antonio, TX9:35 PMIndianapolis, IN$1811One-way0 transfers
3:15 AM40h20San Antonio, TX7:35 PMIndianapolis, IN$2861One-way0 transfers
Travel Information
Compare bus, flight, and train for San Antonio, TX to Indianapolis, IN
Omio recommends booking the flight as it is the most popular option from San Antonio, TX to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from $181. For those with little time consider booking a flight which can get you there in 4h 49m. The ticket price range depends on the travel mode: a bus costs an average of $181, and a train costs an average of $233.
Distance: 999 miles (1609 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$230 Average price Cheapest | $399 Average price | $400 Average price |
25h 10m Average total duration 24h 40m Onboard + 30m Additional time* | 7h 49m Average total duration Fastest 4h 49m Onboard + 3h 0m Additional time* | 33h 19m Average total duration 32h 49m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
San Antonio, TX to Indianapolis, IN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:30AM | Arrival Time 08:25AM | Duration 29h55 | Departure days Wed | Cheapest price $500 |
Operator Greyhound | Departure Time 05:50AM | Arrival Time 12:05PM | Duration 29h15 | Departure days Wed | Cheapest price $336 |
Operator FlixBus | Departure Time 07:45AM | Arrival Time 08:25AM | Duration 47h40 | Departure days Wed | Cheapest price $321 |
Operator Greyhound | Departure Time 07:45AM | Arrival Time 09:55AM | Duration 49h10 | Departure days Wed | Cheapest price $300 |
Operator Greyhound | Departure Time 12:35PM | Arrival Time 09:25PM | Duration 31h50 | Departure days Wed | Cheapest price $299 |
Operator Greyhound | Departure Time 09:15PM | Arrival Time 04:45AM | Duration 30h30 | Departure days Wed | Cheapest price $361 |
Live departures
San Antonio, TX to Indianapolis, IN bus times
The table below shows live departures for San Antonio, TX to Indianapolis, IN buses for today, Wednesday, April 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus+![]() | 12:45 PM San Antonio, Avenue A / Pearl Pkwy, TX | 47h40 | 12:25 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 4 transfers | |
FlixBus · FlixBus · FlixBus+![]() | 12:45 PM San Antonio, Avenue A / Pearl Pkwy, TX | 49h10 | 1:55 PM Indianapolis, Illinois St (Greyhound Bus Station) | 4 transfers | |
undefined · undefined · undefined | 5:35 PM San Antonio, N St Mary's St (Greyhound), TX | 27h00 | 8:35 PM Indianapolis, Illinois St (Greyhound Bus Station) | 2 transfers | |
undefined · undefined · undefined+ FlixBus | 5:35 PM San Antonio, N St Mary's St (Greyhound), TX | 31h50 | 1:25 AM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 3 transfers | |
| Thursday, April 2 | |||||
+ undefined · undefined | 2:15 AM San Antonio, N St Mary's St (Greyhound), TX | 30h30 | 8:45 AM Indianapolis, Illinois St (Greyhound Bus Station) | 2 transfers | |
+ + FlixBus | 2:15 AM San Antonio, N St Mary's St (Greyhound), TX | 34h10 | 12:25 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 2 transfers | |
![]() | 3:15 AM San Antonio, TX | 40h20 | 7:35 PM Indianapolis, IN | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Antonio, TX to Indianapolis, IN by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Apr 08
Why should you book San Antonio, TX to Indianapolis, IN buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from San Antonio, TX to Indianapolis, IN.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from San Antonio, TX to Indianapolis, IN.
Journey information
Overview: Bus from San Antonio, TX to Indianapolis, IN
Buses from San Antonio, TX to Indianapolis, IN run on average 10 times per day, taking around 24h 40m. Cheap bus tickets for this journey start at $181 (€147) if you book in advance.
The earliest bus runs at 01:30, the last at 23:55. The fastest bus covers the 999 miles (1609 km) distance in 27h 0m.
Distance 999 miles (1609 km) |
Average bus duration 24h 40m |
Cheapest ticket price $181 (€147) |
Buses per day 10 |
Fastest bus 27h 0m |
First bus 1:30 AM |
Last bus 11:55 PM |
Bus providers: Greyhound from San Antonio, TX to Indianapolis, INYou can travel by bus between San Antonio, TX to Indianapolis, IN with Greyhound for as low as $181 (€147). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from San Antonio, TX to Indianapolis, IN
Find answers to the most common questions about traveling from San Antonio, TX to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
- The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
- Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
- Indiana State Museum, showcasing the state's history, art, and science through various exhibits
- White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
- Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
- Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
- Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
- Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
- Enjoy a walk along the canal and cultural attractions at White River State Park.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from San Antonio, TX to Indianapolis, IN
Most popular bus connections from San Antonio, TX
More options for your journey from San Antonio, TX to Indianapolis, IN
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