San Diego, CA to Buffalo, NY bus with Greyhound

Wed, Apr 01
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FlixBus
Alsa
BlaBlaCar Bus
Costa Verde
2,000+ travel companies
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The cheapest and fastest buses from San Diego, CA to Buffalo, NY

Showing times and prices for Apr 02

Cheapest price

$762

Average price

$768

Fastest journey

3 d 3 h 15 m

Average duration

3 d 9 h 28 m

Buses per day

2

Distance

3514 km

Cheap tickets

The best way to find a cheap bus ticket from San Diego, CA to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from San Diego, CA to Buffalo, NY will cost around $768 if you buy it on the day, but the cheapest tickets can be found for only $762.

Fast buses

It's difficult to get from San Diego, CA to Buffalo, NY without transferring at least 4 times.

  • Greyhound Mexico
    7:00 AM87h40
    San Diego, CA
    10:40 PMBuffalo, NY
    $7621One-way
    4 transfers
  • Greyhound Mexico
    7:25 PM75h15
    San Diego, CA
    10:40 PMBuffalo, NY
    $7751One-way
    5 transfers

Live departures

San Diego, CA to Buffalo, NY bus times

The table below shows live departures for San Diego, CA to Buffalo, NY buses for today, Wednesday, April 1. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound7:25 PM San Diego, CA
75h15
10:40 PM Buffalo, NY5 transfers
Thursday, April 2
greyhound7:00 AM San Diego, CA
87h40
10:40 PM Buffalo, NY4 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets San Diego, CA to Buffalo, NY by train

Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
Apr 02
Fri
Apr 03
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Apr 04
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Apr 05
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Apr 06
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Apr 07
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Apr 08

Why should you book San Diego, CA to Buffalo, NY buses with Omio?

Greyhound operates all buses services from San Diego, CA to Buffalo, NY.
Omio is an official ticket reseller for all your travel options from San Diego, CA to Buffalo, NY.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Journey information

Overview: Bus from San Diego, CA to Buffalo, NY

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Icon of bus

Take a bus from San Diego, CA to Buffalo, NY and enjoy the approximately 2183 miles (3514 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 00:55, the last at 23:20.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $299 (€243)
Distance
2183 miles (3514 km)
Average bus duration
64h 25m
Buses per day
8
First bus
12:55 AM
Last bus
11:20 PM
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $299 (€243)

Bus providers: Greyhound from San Diego, CA to Buffalo, NYYou can travel by bus between San Diego, CA to Buffalo, NY with Greyhound for as low as $299 (€243). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
71h 30m
Cheapest Price
$325 (€264)
Greyhound frequency
10 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from San Diego, CA to Buffalo, NY

Find answers to the most common questions about traveling from San Diego, CA to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.

FAQs
The earliest bus from San Diego, CA to Buffalo, NY leaves at 12:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Diego, CA to Buffalo, NY leaves at 11:20 PM.
There are 8 buses a day from San Diego, CA to Buffalo, NY which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Diego, CA to Buffalo, NY, you can count on Greyhound for the best way to get you to Buffalo, NY. You can also check all possible bus companies who offer a service between San Diego, CA and Buffalo, NY and compare the amenities they offer before buying a bus ticket.
The cheapest month for a bus from San Diego, CA to Buffalo, NY is November.
Yes, you can take a train between San Diego, CA and Buffalo, NY.
Yes, the following accessibility options are available when taking the bus from San Diego, CA to Buffalo, NY:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Diego, CA to Buffalo, NY for bus company Greyhound.
Whether you can cancel your bus ticket from San Diego, CA to Buffalo, NY depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Diego, CA to Buffalo, NY.
Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to Buffalo, NY:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to Buffalo, NY:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Diego, CA to Buffalo, NY.
You can reserve your seat on the bus from San Diego, CA to Buffalo, NY with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Diego, CA to Buffalo, NY with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Diego, CA to Buffalo, NY with the following bus company: Greyhound.

popular bus stations

Popular bus stations from San Diego, CA to Buffalo, NY

San Diego
Buffalo
The major bus station for departures in San Diego is San Diego, Congress Street (Old Town Park). Find all the information you need to know about services, amenities and connections at San Diego, Congress Street (Old Town Park) for your trip from San Diego to Buffalo.
San Diego, Congress Street (Old Town Park)
information
San Diego, San Ysidro Transit Center
information
San Diego, West Harbor Drive (The Headquarters at Seaport District)
information

More options for your journey from San Diego, CA to Buffalo, NY

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