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The cheapest and fastest buses from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA
Showing times and prices for Apr 06
Cheapest price
$25
Average price
$59
Fastest journey
1 h 5 m
Average duration
1 h 7 m
Buses per day
30
Distance
132 km
Cheap tickets
The best way to find a cheap bus ticket from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA will cost around $59 if you buy it on the day, but the cheapest tickets can be found for only $25.
Fast buses
Of the 30 buses that leave Santa Ana Station, Santa Ana, CA for Santa Fe Depot, San Diego, CA on Mon, Apr 06, 30 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Apr 06 the direct buses cover the 132 km distance in an average of 1 h 7 m but if you time it right, some buses will get you there in just 1 h 5 m .
On Mon, Apr 06 the slowest buses will take 1 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus8:30 PM1h15Santa Ana, E Santa Ana Blvd (Train Station)9:45 PMLa Jolla, UCSD Health La Jolla Station, CA$251One-way0 transfers- FlixBus8:30 PM1h45Santa Ana, E Santa Ana Blvd (Train Station)10:15 PMSan Diego, West Harbor Drive (The Headquarters at Seaport District), CA$251One-way0 transfers
- FlixBus8:30 PM2h15Santa Ana, E Santa Ana Blvd (Train Station)10:45 PMSan Diego, San Ysidro Transit Center$311One-way0 transfers
- FlixBus2:35 PM1h50Santa Ana, E Santa Ana Blvd (Train Station)4:25 PMSan Diego, Congress Street (Old Town Park), CA$371One-way0 transfers
- FlixBus2:35 PM1h20Santa Ana, E Santa Ana Blvd (Train Station)3:55 PMLa Jolla, UCSD Health La Jolla Station, CA$371One-way0 transfers
08:44 AM1h05Tustin, CA9:49 AMSan Diego, CA$551One-way0 transfers- 09:14 PM1h05Tustin, CA10:19 PMSan Diego, CA$551One-way0 transfers
- 05:14 PM1h05Tustin, CA6:19 PMSan Diego, CA$551One-way0 transfers
- 06:24 AM1h10Santa Ana, CA7:34 AMSan Diego, CA$551One-way0 transfers
- 08:39 AM1h10Santa Ana, CA9:49 AMSan Diego, CA$551One-way0 transfers
Travel Information
Compare train and bus for Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA
Omio recommends booking the train as it is the most popular option from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from $15. For those with little time consider booking a bus which can get you there in 1h 57m. The ticket price range depends on the travel mode: a bus costs an average of $15, and a train costs an average of $31.
Distance: 82 miles (132 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
$25 Average price Cheapest | $32 Average price |
2h 27m Average total duration Fastest 1h 57m Onboard + 30m Additional time* | 2h 34m Average total duration 2h 4m Onboard + 30m Additional time* |
 Most popular bus company |  Most popular train company |
Direct Options | Direct Options |
Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Infobus | Departure Time 06:24AM | Arrival Time 07:34AM | Duration 1h10 | Departure days Mon | Cheapest price $55 |
Operator Infobus | Departure Time 06:29AM | Arrival Time 08:04AM | Duration 1h35 | Departure days Mon | Cheapest price $63 |
Operator Infobus | Departure Time 08:39AM | Arrival Time 09:49AM | Duration 1h10 | Departure days Mon | Cheapest price $55 |
Operator Infobus | Departure Time 08:44AM | Arrival Time 09:49AM | Duration 1h05 | Departure days Mon | Cheapest price $55 |
Operator Greyhound | Departure Time 09:40AM | Arrival Time 11:45AM | Duration 2h05 | Departure days Mon | Cheapest price $48 |
Operator Greyhound | Departure Time 10:00AM | Arrival Time 11:45AM | Duration 1h45 | Departure days Mon | Cheapest price $48 |
Operator Infobus | Departure Time 10:39AM | Arrival Time 12:49PM | Duration 2h10 | Departure days Mon | Cheapest price $96 |
Operator Infobus | Departure Time 10:44AM | Arrival Time 12:49PM | Duration 2h05 | Departure days Mon | Cheapest price $96 |
Operator Infobus | Departure Time 12:39PM | Arrival Time 01:49PM | Duration 1h10 | Departure days Mon | Cheapest price $55 |
Operator Infobus | Departure Time 12:44PM | Arrival Time 02:49PM | Duration 2h05 | Departure days Mon | Cheapest price $96 |
Operator FlixBus | Departure Time 02:35PM | Arrival Time 04:25PM | Duration 1h50 | Departure days Mon | Cheapest price $37 |
Operator Infobus | Departure Time 02:39PM | Arrival Time 04:19PM | Duration 1h40 | Departure days Mon | Cheapest price $63 |
Operator Infobus | Departure Time 02:44PM | Arrival Time 04:49PM | Duration 2h05 | Departure days Mon | Cheapest price $96 |
Operator Infobus | Departure Time 05:09PM | Arrival Time 06:49PM | Duration 1h40 | Departure days Mon | Cheapest price $63 |
Operator Infobus | Departure Time 05:14PM | Arrival Time 06:19PM | Duration 1h05 | Departure days Mon | Cheapest price $55 |
Operator Infobus | Departure Time 07:09PM | Arrival Time 09:19PM | Duration 2h10 | Departure days Mon | Cheapest price $96 |
Operator Infobus | Departure Time 07:14PM | Arrival Time 09:19PM | Duration 2h05 | Departure days Mon | Cheapest price $96 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 09:45PM | Duration 1h15 | Departure days Mon | Cheapest price $25 |
Operator Infobus | Departure Time 09:09PM | Arrival Time 11:19PM | Duration 2h10 | Departure days Mon | Cheapest price $96 |
Operator Infobus | Departure Time 09:14PM | Arrival Time 10:19PM | Duration 1h05 | Departure days Mon | Cheapest price $55 |
Operator Greyhound | Departure Time 09:40PM | Arrival Time 11:50PM | Duration 2h10 | Departure days Mon | Cheapest price $40 |
Operator Greyhound | Departure Time 10:05PM | Arrival Time 11:50PM | Duration 1h45 | Departure days Mon | Cheapest price $40 |
Live departures
Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA bus times
The table below shows live departures for Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA buses for tomorrow, Sunday, April 5. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 0 | 1:24 PM Santa Ana, CA | 1h10 | 2:34 PM San Diego, CA | 0 transfersDirect | |
| 0 | 1:29 PM Tustin, CA | 1h35 | 3:04 PM San Diego, CA | 0 transfersDirect | |
| 0 | 3:39 PM Santa Ana, CA | 1h10 | 4:49 PM San Diego, CA | 0 transfersDirect | |
| 0 | 3:44 PM Tustin, CA | 1h05 | 4:49 PM San Diego, CA | 0 transfersDirect | |
| 4:40 PM Anaheim, Regional Transportation Intermodal Center (ARTIC) | 2h40 | 7:20 PM San Diego, San Ysidro Transit Center | 0 transfersDirect | |
| 4:40 PM Anaheim, Regional Transportation Intermodal Center (ARTIC) | 2h05 | 6:45 PM San Diego, Congress Street (Old Town Park), CA | 0 transfersDirect | |
| 5:00 PM Santa Ana, E Santa Ana Blvd (Train Station) | 1h45 | 6:45 PM San Diego, Congress Street (Old Town Park), CA | 0 transfersDirect | |
| 5:00 PM Santa Ana, E Santa Ana Blvd (Train Station) | 2h20 | 7:20 PM San Diego, San Ysidro Transit Center | 0 transfersDirect | |
| 0 | 5:39 PM Santa Ana, CA | 2h10 | 7:49 PM San Diego, CA | 0 transfersDirect | |
| 0 | 5:44 PM Tustin, CA | 2h05 | 7:49 PM San Diego, CA | 0 transfersDirect | |
| 0 | 7:39 PM Santa Ana, CA | 1h10 | 8:49 PM San Diego, CA | 0 transfersDirect | |
| 0 | 7:44 PM Tustin, CA | 2h05 | 9:49 PM San Diego, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA by train or bus
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Why should you book Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA buses with Omio?
Greyhound as well as FlixBus or Infobus offer buses services from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA.
Omio is an official ticket reseller for all your travel options from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus or Infobus to find the best option for your trip from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train and bus to ensure you get the best deal for traveling from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA.
Why book with Omio over Wanderu, Trainline or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus or Infobus to find the best option for your trip from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA.
Journey information
Overview: Bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA
USAUSA
Buses from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA run on average 17 times per day, taking around 1h 57m. Cheap bus tickets for this journey start at $15 (€12) if you book in advance.
There are 16 buses per day. The earliest bus runs at 04:20, the last at 22:35. The fastest bus covers the 82 miles (132 km) distance in 1h 15m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 82 miles (132 km) |
Average bus duration 1h 57m |
Cheapest ticket price $15 (€12) |
Buses per day 17 |
Direct buses 16 |
Fastest bus 1h 15m |
First bus 4:20 AM |
Last bus 10:35 PM |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, FlixBus, Infobus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CAYou can travel by bus between Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA with Greyhound, FlixBus, Infobus for as low as $15 (€12). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
1h 15m
Cheapest Price
$15 (€12)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Infobus
About
Infobus is an international IT company that operates as an online service for finding and purchasing bus, train, and plane tickets, rather than being a bus company itself. Established in 2002, Infobus acts as an intermediary between passengers and various transport carriers, particularly helping smaller bus companies offer online booking services. They utilize their own "BusSystem" to manage routes and ticket sales globally. Infobus covers over 30 countries and 300 cities, offering a wide range of routes and daily departures. While amenities can vary by carrier, Infobus aims to provide affordable and convenient travel with features like online booking, 24/7 support, and prompt notifications.
Luggage & cancellation policy
Average Duration
1h 20m
Cheapest Price
$40 (€32)
Infobus frequency
18 a day
Luggage included
One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
Additional luggage
10€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Transport for wheelchairs and mobility aids.
Bikes
Bikes are allowed; may require prior reservation and an additional fee.
Pets
Small pets allowed in carriers; larger pets may require a separate ticket.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
1h 45m
Cheapest Price
$49 (€40)
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
FAQs: Bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA
Find answers to the most common questions about traveling from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Fe Depot, San Diego, CA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA can start from as little as $15 (€12) when you book in advance. The average bus ticket price for Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA is $25 (€21) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA is 1h 15m to travel the 82 miles (132 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA leaves at 4:20 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA leaves at 10:35 PM.
Yes, there are 16 direct buses a day from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA with FlixBus, Infobus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA, you can count on Greyhound, FlixBus, Infobus for the best way to get you to Santa Fe Depot, San Diego, CA. You can also check all possible bus companies who offer a service between Santa Ana Station, Santa Ana, CA and Santa Fe Depot, San Diego, CA and compare the amenities they offer before buying a bus ticket.
A day trip to Santa Fe Depot, San Diego, CA from Santa Ana Station, Santa Ana, CA is worth doing with a journey time of 1h 15m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA is April.
It's helpful to compare your options as there are 2 ways to travel between Santa Ana Station, Santa Ana, CA and Santa Fe Depot, San Diego, CA including taking a train and bus.
Yes, the following accessibility options are available when taking the bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA:
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA for bus company Greyhound, FlixBus, Infobus.
Whether you can cancel your bus ticket from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA depends on the bus companies:
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus, Infobus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA.
Yes, the following luggage options are included when booking a bus ticket from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA:
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA:
- Infobus
- 10€ per additional bag.
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA. The following conditions apply:
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA with the following bus company: Greyhound, FlixBus, Infobus
Yes, there are USB plugs on board the bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA with the following bus company: Greyhound, FlixBus, Infobus.
Yes, there is Wifi on board the bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA with the following bus company: Greyhound, FlixBus, Infobus.
Most popular bus connections from Santa Ana Station, Santa Ana, CA
Most popular buses to and from Santa Fe Depot, San Diego, CA and Santa Ana Station, Santa Ana, CA
Most popular bus connections to Santa Fe Depot, San Diego, CA
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