The cheapest and fastest buses from Southampton to Brussels
Cheapest price
$49
Average price
$59
Fastest journey
11 h 15 m
Average duration
11 h 23 m
Buses per day
2
Distance
404 km
The best way to find a cheap bus ticket from Southampton to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Southampton to Brussels will cost around $59 if you buy it on the day, but the cheapest tickets can be found for only $49.
It's difficult to get from Southampton to Brussels without transferring at least once.
7:15 AM11h15Southampton6:30 PMBrussels$491One-way2 transfers
7:00 AM11h30Southampton6:30 PMBrussels$691One-way1 transfer
7:15 AM11h15Southampton6:30 PMBrussels$491One-way2 transfers
7:00 AM11h30Southampton6:30 PMBrussels$691One-way1 transfer
Live departures
Southampton to Brussels bus times
The table below shows live departures for Southampton to Brussels buses for tomorrow, Wednesday, April 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:00 AM Southampton | 11h30 | 6:30 PM Brussels | 1 transfer | |
![]() | 7:15 AM Southampton | 11h15 | 6:30 PM Brussels | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Southampton to Brussels by flight
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 02
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Apr 08
Journey information
Overview: Bus from Southampton to Brussels
Take a bus from Southampton to Brussels and enjoy the approximately 251 miles (404 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 02:00, the last at 23:40.
Distance 251 miles (404 km) |
Buses per day 2 |
First bus 2:00 AM |
Last bus 11:40 PM |
FAQs: Bus from Southampton to Brussels
Find answers to the most common questions about traveling from Southampton to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

- Grand Place, a UNESCO World Heritage site known for its opulent guildhalls and vibrant flower market
- Atomium, an iconic structure and museum offering panoramic views of the city
- Manneken Pis, a famous bronze statue symbolizing the irreverent spirit of Brussels
- Royal Palace of Brussels, the official palace of the Belgian king with impressive architecture and gardens
- Magritte Museum, dedicated to the works of surrealist artist René Magritte, featuring an extensive collection of his paintings and drawings.
- Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art
- Enjoy a leisurely stroll through the picturesque Parc du Cinquantenaire, home to impressive arches and museums
- Sample Belgian chocolates at one of the city's renowned chocolatiers
- Discover the lively atmosphere of the Saint-Géry district, filled with trendy bars and cafes
- Attend a performance at the historic La Monnaie opera house, showcasing world-class productions.
Most popular bus connections from Southampton
More options for your journey from Southampton to Brussels
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