4.9
4.6The cheapest and fastest buses from St. Louis, MO to San Diego, CA
Cheapest price
$237
Average price
$263
Fastest journey
1 d 19 h
Average duration
1 d 22 h 50 m
Buses per day
2
Distance
2512 km
The best way to find a cheap bus ticket from St. Louis, MO to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to San Diego, CA will cost around $263 if you buy it on the day, but the cheapest tickets can be found for only $237.
Of the 2 buses that leave St. Louis, MO for San Diego, CA on Sun, Apr 05, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Apr 05 the direct buses cover the 2512 km distance in an average of 1 d 22 h 50 m but if you time it right, some buses will get you there in just 1 d 19 h .
On Sun, Apr 05 the slowest buses will take 2 d 2 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
7:20 AM43h00St. Louis, MO2:20 AMSan Diego, CA$2371One-way0 transfers- 10:30 PM50h40St. Louis, MO1:10 AMSan Diego, CA$2891One-way0 transfers
- 7:20 AM43h00St. Louis, MO2:20 AMSan Diego, CA$2371One-way0 transfers
- 10:30 PM50h40St. Louis, MO1:10 AMSan Diego, CA$2891One-way0 transfers
Travel Information
Compare train, bus, and flight for St. Louis, MO to San Diego, CA
Omio recommends booking the train as it is the most popular option from St. Louis, MO to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from $152. For those with little time consider booking a flight which can get you there in 7h 22m. The ticket price range depends on the travel mode: a bus costs an average of $152, and a train costs an average of $217.
Distance: 1560 miles (2512 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$304 Average price Cheapest | $672 Average price | $336 Average price |
50h 1m Average total duration 49h 31m Onboard + 30m Additional time* | 60h 54m Average total duration 60h 24m Onboard + 30m Additional time* | 10h 22m Average total duration Fastest 7h 22m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
St. Louis, MO to San Diego, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:20AM | Arrival Time 10:15PM | Duration 46h55 | Departure days Fri, Sat | Cheapest price $248 |
Operator Greyhound | Departure Time 09:10AM | Arrival Time 10:15PM | Duration 63h05 | Departure days Fri, Sat | Cheapest price $250 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 05:45PM | Duration 51h45 | Departure days Fri, Sat | Cheapest price $253 |
Operator Greyhound | Departure Time 04:30PM | Arrival Time 05:50PM | Duration 51h20 | Departure days Fri, Sat | Cheapest price $252 |
Live departures
St. Louis, MO to San Diego, CA bus times
The table below shows live departures for St. Louis, MO to San Diego, CA buses for today, Saturday, April 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| undefined · undefined · undefined · undefined | 2:10 PM St. Louis, Lambert International Airport | 52h35 | 6:45 PM San Diego, Congress Street (Old Town Park), CA | 3 transfers | |
 FlixBus+undefined · undefined · undefined | 9:00 PM St. Louis, S 15th St (Civic center) | 51h45 | 12:45 AM San Diego, Congress Street (Old Town Park), CA | 3 transfers | |
| FlixBus+undefined · undefined+FlixBus | 9:00 PM St. Louis, S 15th St (Civic center) | 52h10 | 1:10 AM San Diego, Congress Street (Old Town Park), CA | 4 transfers | |
| undefined · undefined · undefined+FlixBus | 9:30 PM St. Louis, S 15th St (Civic center) | 55h45 | 5:15 AM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA | 3 transfers | |
| Sunday, April 5 | |||||
| 7:20 AM St. Louis, MO | 43h00 | 2:20 AM San Diego, CA | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to San Diego, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 05
Apr 06
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Apr 11
Why should you book St. Louis, MO to San Diego, CA buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to San Diego, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to San Diego, CA.
Journey information
Overview: Bus from St. Louis, MO to San Diego, CA
USAUSA
Buses from St. Louis, MO to San Diego, CA run on average 12 times per day, taking around 49h 31m. Cheap bus tickets for this journey start at $152 (€124) if you book in advance.
The earliest bus runs at 01:20, the last at 23:30. The fastest bus covers the 1560 miles (2512 km) distance in 43h 0m.
Distance 1560 miles (2512 km) |
Average bus duration 49h 31m |
Cheapest ticket price $152 (€124) |
Buses per day 12 |
Fastest bus 43h 0m |
First bus 1:20 AM |
Last bus 11:30 PM |
Bus providers: Greyhound from St. Louis, MO to San Diego, CAYou can travel by bus between St. Louis, MO to San Diego, CA with Greyhound for as low as $152 (€124). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from St. Louis, MO to San Diego, CA
Find answers to the most common questions about traveling from St. Louis, MO to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- enjoy a harbor cruise for stunning views of the skyline and naval ships
- hike the scenic trails at Torrey Pines State Natural Reserve
- visit the Birch Aquarium to learn about marine life and ocean conservation
- experience the thrill of a whale watching tour off the coast.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from St. Louis, MO to San Diego, CA
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to San Diego, CA
Here are some other resources that might have the information you need
Most popular buses to and from San Diego, CA and St. Louis, MO
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