WILMINGTON to FLORENCE bus from $178 (€145) with Omio

2,000+ travel companies

Scan to get our free app

Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.

App Store

4.9

42K ratings

Google Play

4.6

136K reviews

Live departures

Wilmington, DE to Florence, SC bus times

The table below shows live departures for Wilmington, DE to Florence, SC buses for today, Friday, April 3. You can also manually refresh the results below to see updated bus journeys.

Last updated at

Provider	Departs	Duration	Arrives	Transfers	Tickets
	9:25 PM Wilmington, DE	14h20	11:45 AM Florence, SC	2 transfers
This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Wilmington, DE to Florence, SC by train

Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Apr 04

Sun
Apr 05

Mon
Apr 06

Tue
Apr 07

Wed
Apr 08

Thu
Apr 09

Fri
Apr 10

Journey information

Overview: Bus from Wilmington, DE to Florence, SC

USA

Take a bus from Wilmington, DE to Florence, SC and enjoy the approximately 448 miles (722 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 00:05, the last at 21:25.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.

Price information

Cheapest alternative travel mode

Train from $178 (€145)

Distance

448 miles (722 km)

Buses per day

First bus

12:05 AM

Last bus

9:25 PM

Price information

Cheapest alternative travel mode

Train from $178 (€145)

FAQs: Bus from Wilmington, DE to Florence, SC

Find answers to the most common questions about traveling from Wilmington, DE to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

The earliest bus from Wilmington, DE to Florence, SC leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.

The latest bus from Wilmington, DE to Florence, SC leaves at 9:25 PM.

The cheapest month for a bus from Wilmington, DE to Florence, SC is October.

Yes, you can take a train between Wilmington, DE and Florence, SC.

No, the bus from Wilmington, DE to Florence, SC has no accessibility options.

No, there are no bathrooms on board the bus from Wilmington, DE to Florence, SC.

No, bikes are not allowed on board the bus from Wilmington, DE to Florence, SC.

Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.

No, there is no food available to purchase on board the bus from Wilmington, DE to Florence, SC.

No, luggage for the bus from Wilmington, DE to Florence, SC needs to be booked in addition.

No, there are no additional luggage options for the bus from Wilmington, DE to Florence, SC.

Unfortunately, pets are not allowed on the bus from Wilmington, DE to Florence, SC.

No, there are no USB plugs on board the bus from Wilmington, DE to Florence, SC.

No, there is no WiFi on board the bus from Wilmington, DE to Florence, SC.

popular bus stations

Popular bus stations from Wilmington, DE to Florence, SC

Wilmington

Florence

The major bus station for departures in Wilmington is Wilmington, Amtrak Station @ ML King-French. Find all the information you need to know about services, amenities and connections at Wilmington, Amtrak Station @ ML King-French for your trip from Wilmington to Florence.

Wilmington, Amtrak Station @ ML King-French

information

Most popular bus connections from Wilmington, DE

Bus Wilmington, DE - New York, NY

Bus Wilmington, DE - Los Angeles, CA

Bus Wilmington, DE - Philadelphia, PA

Bus Wilmington, DE - Newark, NJ

Bus Wilmington, DE - Albany, NY

More options for your journey from Wilmington, DE to Florence, SC

Here are some other resources that might have the information you need

Return journeys for buses from Florence, SC to Wilmington, DE

Tickets and more information for coaches to Wilmington, DE

Tickets and more information for coaches to Florence, SC

Most popular buses to and from Florence, SC and Wilmington, DE

Bus Wilmington, DE - Boston, MA

Bus Wilmington, DE - New York, NY

Bus Wilmington, DE - Los Angeles, CA

Bus Wilmington, DE - Chicago, IL

Bus Wilmington, DE - Washington, DC

Bus Wilmington, DE - Philadelphia, PA

Bus Wilmington, DE - Dallas, TX

Bus Wilmington, DE - Orlando, FL

Bus Wilmington, DE - Atlanta, GA

Bus Wilmington, DE - Miami, FL

Bus Wilmington, DE - Tampa, FL

Bus Wilmington, DE - Baltimore, MD

Bus Wilmington, DE - Newark, NJ

Bus Wilmington, DE - Denver, CO

Bus Wilmington, DE - Charlotte, NC

Bus Wilmington, DE - Nashville, TN

Bus Wilmington, DE - Raleigh, NC

Bus Wilmington, DE - Pittsburgh, PA

Bus Wilmington, DE - Jacksonville, FL

Bus Wilmington, DE - Richmond, VA

Bus Wilmington, DE - Cleveland, OH

Bus Wilmington, DE - Fort Lauderdale, FL

Bus Boston, MA - Florence, SC

Bus New York, NY - Florence, SC

Bus Washington, DC - Florence, SC

Bus Philadelphia, PA - Florence, SC

Bus Orlando, FL - Florence, SC

Bus Miami, FL - Florence, SC

Bus Tampa, FL - Florence, SC

Bus Baltimore, MD - Florence, SC

Bus Newark, NJ - Florence, SC

Bus Milwaukee, WI - Florence, SC

Bus Charlotte, NC - Florence, SC

Bus Raleigh, NC - Florence, SC

Bus Pittsburgh, PA - Florence, SC

Bus Jacksonville, FL - Florence, SC

Bus Richmond, VA - Florence, SC

Bus Cleveland, OH - Florence, SC

Bus Fort Lauderdale, FL - Florence, SC

Bus Syracuse, NY - Florence, SC

Bus West Palm Beach, FL - Florence, SC

Bus Colorado Springs, CO - Florence, SC

Bus Savannah, GA - Florence, SC

Bus Fayetteville, NC - Florence, SC

Most popular bus connections to Florence, SC

Bus Raleigh, NC - Florence, SC

Bus Richmond, VA - Florence, SC

Bus Savannah, GA - Florence, SC

Bus Charlotte, NC - Florence, SC

Home Buses Buses in USA Bus tickets to Florence, SCWilmington, DE to Florence, SC bus

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

Wilmington, DE to Florence, SC bus

Live departures

Wilmington, DE to Florence, SC bus times

Compare prices and tickets Wilmington, DE to Florence, SC by train

Journey information

Overview: Bus from Wilmington, DE to Florence, SC

FAQs: Bus from Wilmington, DE to Florence, SC

What’s the earliest bus time from Wilmington, DE to Florence, SC?

What’s the latest bus time from Wilmington, DE to Florence, SC?

What is the cheapest month to take a bus from Wilmington, DE to Florence, SC?

Is there a bus from Wilmington, DE to Florence, SC?

Are there accessibility options when taking a bus from Wilmington, DE to Florence, SC?

Are there toilets on board the bus from Wilmington, DE to Florence, SC?

Can I bring my bike on board the bus from Wilmington, DE to Florence, SC?

How can I find the cheapest bus tickets to get from Wilmington, DE to Florence, SC?

Is there food available to purchase on board the bus from Wilmington, DE to Florence, SC?

Is luggage included in the bus ticket price from Wilmington, DE to Florence, SC?

Can I book additional luggage for the bus from Wilmington, DE to Florence, SC?

Can I bring my pet on board the bus from Wilmington, DE to Florence, SC?

Are there USB plugs on board the bus from Wilmington, DE to Florence, SC?

Is there WiFi on board the bus from Wilmington, DE to Florence, SC?