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Journey information
Overview: Santa Ana, CA to Chicago, IL flight
USAUSA
Flights from Santa Ana, CA to Chicago, IL depart on average 50 times per day, taking around 4h 9m. Cheap flight tickets for this journey start at $115 (€94) if you book in advance.
There are 5 flights per day. The earliest flight runs at 05:00, the last at 22:10. The fastest flight covers the 1731 miles (2787 km) distance in 4h 3m. March is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1731 miles (2787 km) |
Average flight duration 4h 9m |
Cheapest ticket price $115 (€94) |
Flights per day 50 |
Direct flights 5 |
Fastest flight 4h 3m |
Cheapest month March |
First flight 5:00 AM |
Last flight 10:10 PM |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
The cheapest and fastest flights from Santa Ana, CA to Chicago, IL
Showing times and prices for Apr 11
Cheapest price
$115
Average price
$115
Fastest journey
19 h 40 m
Average duration
19 h 40 m
Flights per day
1
Distance
2787 km
Cheap tickets
The best way to find a cheap flight ticket from Santa Ana, CA to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Ana, CA to Chicago, IL will cost around $115 if you buy it on the day, but the cheapest tickets can be found for only $115.
Fast flights
Of the 1 flights that leave Santa Ana, CA for Chicago, IL onSat, Apr 11, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Apr 11 the direct flights cover the 2787 km distance in an average of 19 h 40 m but if you time it right, some flights will get you there in just 19 h 40 m .
On Sat, Apr 11 the longest flights will take 19 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
12:37 AM19h40Santa Ana, CA8:17 PMChicago, IL$1151One-way0 transfers
- 12:37 AM19h40Santa Ana, CA8:17 PMChicago, IL$1151One-way0 transfers
Travel Information
Compare train, bus, and flight for Santa Ana, CA to Chicago, IL
Omio recommends booking the train as it is the most popular option from Santa Ana, CA to Chicago, IL among Omio's users. If you are prioritising price take the train with prices starting from $203. For those with little time consider booking a flight which can get you there in 4h 9m. The ticket price range depends on the travel mode: a train costs an average of $203, and a flight costs an average of $115.
Distance: 1731 miles (2787 km)
Compare flight with
| Flight | Most popular Train | Bus |
|---|---|---|
$393 Average price | $255 Average price Cheapest | $377 Average price |
7h 9m Average total duration Fastest 4h 9m Onboard + 3h 0m Additional time* | 43h 22m Average total duration 42h 52m Onboard + 30m Additional time* | 51h 20m Average total duration 50h 50m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Santa Ana, CA to Chicago, IL flight times
The table below shows live departures for Santa Ana, CA to Chicago, IL flights for today, Saturday, April 4. You can also manually refresh the results below to see updated flight journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 AA1382 · AA1250 | 1:45 PM John Wayne Airport | 6h43 | 8:28 PM O'Hare International Airport | 1 transfer | |
| AA628 · AA1392 | 1:45 PM John Wayne Airport | 6h19 | 8:04 PM O'Hare International Airport | 1 transfer | |
 UA661 | 1:45 PM John Wayne Airport | 9h45 | 11:30 PM O'Hare International Airport | 0 transfersDirect | |
| UA661 · UA254 | 1:45 PM John Wayne Airport | 11h52 | 1:37 AM O'Hare International Airport | 1 transfer | |
 AS1325 · AS410 | 1:45 PM John Wayne Airport | 9h41 | 11:26 PM O'Hare International Airport | 1 transfer | |
| UA587 | 1:45 PM John Wayne Airport | 4h15 | 6:00 PM O'Hare International Airport | 0 transfersDirect | |
| AS1325 · AS538 | 1:45 PM John Wayne Airport | 15h14 | 4:59 AM O'Hare International Airport | 1 transfer | |
| AA1382 · AA2966 | 1:45 PM John Wayne Airport | 8h58 | 10:43 PM O'Hare International Airport | 1 transfer | |
| AA628 · AA1015 | 1:45 PM John Wayne Airport | 9h03 | 10:48 PM O'Hare International Airport | 1 transfer | |
| UA513 · UA2865 | 2:00 PM John Wayne Airport | 5h52 | 7:52 PM O'Hare International Airport | 1 transfer | |
| UA694 · UA4802 · UA1840 | 2:15 PM John Wayne Airport | 11h35 | 1:50 AM O'Hare International Airport | 2 transfers | |
| UA694 · UA2382 · UA706 | 2:15 PM John Wayne Airport | 11h10 | 1:25 AM O'Hare International Airport | 2 transfers | |
| UA694 · UA1394 | 2:15 PM John Wayne Airport | 9h33 | 11:48 PM O'Hare International Airport | 1 transfer | |
| UA694 · UA1147 · UA1210 | 2:15 PM John Wayne Airport | 14h15 | 4:30 AM O'Hare International Airport | 2 transfers | |
| UA694 · UA500 · UA1686 | 2:15 PM John Wayne Airport | 11h06 | 1:21 AM O'Hare International Airport | 2 transfers | |
| AA2209 · AA2438 | 2:45 PM John Wayne Airport | 8h12 | 10:57 PM O'Hare International Airport | 1 transfer | |
| AA2209 · AA1199 | 2:45 PM John Wayne Airport | 9h55 | 12:40 AM O'Hare International Airport | 1 transfer | |
| AA2590 | 2:45 PM John Wayne Airport | 4h10 | 6:55 PM O'Hare International Airport | 0 transfersDirect | |
| UA700 · UA1493 | 3:00 PM John Wayne Airport | 10h15 | 1:15 AM O'Hare International Airport | 1 transfer | |
| UA700 · UA1333 | 3:00 PM John Wayne Airport | 7h05 | 10:05 PM O'Hare International Airport | 1 transfer | |
| AS702 · AS410 | 3:05 PM John Wayne Airport | 8h21 | 11:26 PM O'Hare International Airport | 1 transfer | |
| AS702 · AS538 | 3:05 PM John Wayne Airport | 13h54 | 4:59 AM O'Hare International Airport | 1 transfer | |
| AA3218 · AA2966 | 3:17 PM John Wayne Airport | 7h26 | 10:43 PM O'Hare International Airport | 1 transfer | |
| UA489 · UA617 | 4:00 PM John Wayne Airport | 6h04 | 10:04 PM O'Hare International Airport | 1 transfer | |
| UA489 · UA1023 | 4:00 PM John Wayne Airport | 7h58 | 11:58 PM O'Hare International Airport | 1 transfer | |
| AA1686 · AA2966 | 4:23 PM John Wayne Airport | 6h20 | 10:43 PM O'Hare International Airport | 1 transfer | |
| AA1686 · AA1779 | 4:23 PM John Wayne Airport | 9h17 | 1:40 AM O'Hare International Airport | 1 transfer | |
| AA543 · AA1789 | 4:48 PM John Wayne Airport | 8h16 | 1:04 AM O'Hare International Airport | 1 transfer | |
| AA543 · AA1015 | 4:48 PM John Wayne Airport | 6h00 | 10:48 PM O'Hare International Airport | 1 transfer | |
| AS1378 · AS538 | 5:26 PM John Wayne Airport | 11h33 | 4:59 AM O'Hare International Airport | 1 transfer | |
| UA2426 | 5:50 PM John Wayne Airport | 4h05 | 9:55 PM O'Hare International Airport | 0 transfersDirect | |
| AA3197 · AA1779 | 5:55 PM John Wayne Airport | 7h45 | 1:40 AM O'Hare International Airport | 1 transfer | |
| AA3197 · AA1489 | 5:55 PM John Wayne Airport | 8h30 | 2:25 AM O'Hare International Airport | 1 transfer | |
| AA2285 | 6:41 PM John Wayne Airport | 4h09 | 10:50 PM O'Hare International Airport | 0 transfersDirect | |
| AS548 · AS538 | 7:07 PM John Wayne Airport | 9h52 | 4:59 AM O'Hare International Airport | 1 transfer | |
| UA742 · UA2197 | 7:15 PM John Wayne Airport | 7h16 | 2:31 AM O'Hare International Airport | 1 transfer | |
| UA742 · UA1752 | 7:15 PM John Wayne Airport | 9h00 | 4:15 AM O'Hare International Airport | 1 transfer | |
| AA456 · AA3089 | 7:26 PM John Wayne Airport | 6h41 | 2:07 AM O'Hare International Airport | 1 transfer | |
| AA456 · AA1789 | 7:26 PM John Wayne Airport | 5h38 | 1:04 AM O'Hare International Airport | 1 transfer | |
| UA1559 · UA1206 | 7:39 PM John Wayne Airport | 8h58 | 4:37 AM O'Hare International Airport | 1 transfer | |
| AA2264 · AA1489 | 7:47 PM John Wayne Airport | 6h38 | 2:25 AM O'Hare International Airport | 1 transfer | |
| AA2264 · AA2951 | 7:47 PM John Wayne Airport | 7h58 | 3:45 AM O'Hare International Airport | 1 transfer | |
| AA2264 · AA1573 | 7:47 PM John Wayne Airport | 8h49 | 4:36 AM O'Hare International Airport | 1 transfer | |
| UA1937 · UA2258 | 8:21 PM John Wayne Airport | 7h37 | 3:58 AM O'Hare International Airport | 1 transfer | |
| UA1937 · UA1411 | 8:21 PM John Wayne Airport | 5h56 | 2:17 AM O'Hare International Airport | 1 transfer | |
| UA1383 · UA1482 | 9:38 PM John Wayne Airport | 6h51 | 4:29 AM O'Hare International Airport | 1 transfer | |
| UA1383 · UA1995 · UA2102 | 9:38 PM John Wayne Airport | 13h00 | 10:38 AM O'Hare International Airport | 2 transfers | |
| UA1352 | 9:40 PM John Wayne Airport | 4h05 | 1:45 AM O'Hare International Airport | 0 transfersDirect | |
| AA2861 · AA1573 | 9:47 PM John Wayne Airport | 6h49 | 4:36 AM O'Hare International Airport | 1 transfer | |
| NK1631 · NK1255 · NK1156 | 9:53 PM John Wayne Airport | 21h23 | 7:16 PM O'Hare International Airport | 2 transfers | |
| AA2212 | 10:24 PM John Wayne Airport | 4h12 | 2:36 AM O'Hare International Airport | 0 transfersDirect | |
| UA643 · UA787 | 10:29 PM John Wayne Airport | 7h16 | 5:45 AM O'Hare International Airport | 1 transfer | |
| UA5351 · UA406 · UA2102 | 11:39 PM John Wayne Airport | 10h59 | 10:38 AM O'Hare International Airport | 2 transfers | |
| UA5351 · UA1995 · UA2102 | 11:39 PM John Wayne Airport | 10h59 | 10:38 AM O'Hare International Airport | 2 transfers | |
| Sunday, April 5 | |||||
| AA2094 · AA3205 | 12:01 AM John Wayne Airport | 10h24 | 10:25 AM O'Hare International Airport | 1 transfer | |
| AA2094 · AA1614 | 12:01 AM John Wayne Airport | 5h50 | 5:51 AM O'Hare International Airport | 1 transfer | |
| 12:37 AM Santa Ana, CA | 19h40 | 8:17 PM Chicago, IL | 0 transfersDirect | |
| AS630 · AS328 | 12:46 AM John Wayne Airport | 10h53 | 11:39 AM O'Hare International Airport | 1 transfer | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Ana, CA to Chicago, IL by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Santa Ana, CA to Chicago, IL flights with Omio?
American Airlines operates all flights services from Santa Ana, CA to Chicago, IL.
Omio is an official ticket reseller for all your travel options from Santa Ana, CA to Chicago, IL.
Why book with Omio vs American Airlines?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare American Airlines with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Santa Ana, CA to Chicago, IL.
Why book with Omio over Trip, Edreams or Skyscanner?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Santa Ana, CA to Chicago, IL.
Airlines: American Airlines from Santa Ana, CA to Chicago, ILFind the best flights between Santa Ana, CA to Chicago, IL with Omio's travel partners American Airlines from $115 (€94). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
American Airlines
About
American Airlines is one of the largest airlines in the world, connecting travelers to hundreds of destinations across the United States, Latin America, Europe, Asia, and beyond. Operating from major hubs such as Dallas/Fort Worth, Miami, and Charlotte, American offers a wide range of travel options. Passengers can choose from Economy with affordable fares, Premium Economy with extra space, or Business and First Class featuring flat-bed seats, premium dining, and lounge access. With a modern fleet and membership in the oneworld alliance, American Airlines combines global reach with comfort and reliability.
Luggage & cancellation policy
Average Duration
11h 31m
Cheapest Price
$206 (€168)
American Airlines frequency
23 a day
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item (18 x 14 x 8 inches) included in most fares
Additional luggage
Checked bags fees vary by route. First checked bag typically $30, second $40 on domestic flights
Cancellation Policy
Basic Economy tickets cannot be changed or refunded. Other fares allow changes with fee, refunds subject to fare rules.
Pregnant on board
Passengers can fly up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required within 7 days of departure if within 4 weeks of due date.
Unaccompagned minor
Children ages 5-14 can travel alone using American Airlines Unaccompanied Minor Service. Service fee is $150 each way.
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
American Airlines provides wheelchair assistance and special services for passengers with disabilities. Assistance must be requested at least 48 hours before departure.
Pets
Small dogs and cats allowed in cabin for $125 fee. Must be in approved carrier under seat. Service animals allowed.
Entertaiment on board
FAQs: Santa Ana, CA to Chicago, IL Flight
Find answers to the most common questions about traveling from Santa Ana, CA to Chicago, IL by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
Cheap plane tickets from Santa Ana, CA to Chicago, IL can start from as little as $115 (€94) when you book in advance. The average flight ticket price for Santa Ana, CA to Chicago, IL is $393 (€320) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from Santa Ana, CA to Chicago, IL is 4h 3m to travel the 1731 miles (2787 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from Santa Ana, CA to Chicago, IL leaves at 5:00 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Santa Ana, CA to Chicago, IL leaves at 10:10 PM.
Yes, there are 5 direct flights a day from Santa Ana, CA to Chicago, IL with American Airlines. Schedules can vary on holidays or weekends with fewer direct flights.
When taking a flight from Santa Ana, CA to Chicago, IL, you can count on American Airlines for the best way to get you to Chicago, IL. You can also check all possible airlines who offer a service between Santa Ana, CA and Chicago, IL and compare the amenities they offer before buying a plane ticket.
Flights from Santa Ana, CA to Chicago, IL generally leave from John Wayne Airport and arrive in O'Hare International Airport.John Wayne Airport is 1 miles (3 km) away from Santa Ana, CA city centre and O'Hare International Airport is 1 miles (3 km) from Chicago, IL city centre.
The cheapest month for a flight from Santa Ana, CA to Chicago, IL is March.
It's helpful to compare your options as there are 3 ways to travel between Santa Ana, CA and Chicago, IL including taking a train, bus, and flight.
Since neither Santa Ana, CA nor Chicago, IL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is a time difference of 2 h between Santa Ana, CA and Chicago, IL all year round.
The best events to attend in Chicago, IL include:
- Chicago Air and Water Show, an exhilarating display of military and civilian aircraft performing daring maneuvers over Lake Michigan
- Lollapalooza, a massive music festival featuring top artists across multiple genres in Grant Park
- Chicago Gourmet, a premier culinary event celebrating the city's vibrant food scene with tastings, cooking demonstrations, and wine pairings.
The best holidays to experience in Chicago, IL include:
- Memorial Day, the unofficial start of summer with vibrant outdoor activities and events
- Independence Day, spectacular fireworks and festive celebrations throughout the city
- Labor Day, a lively atmosphere with various festivals and pleasant weather.
The best season to visit Chicago, IL is Spring or Summer. The best weather to explore Chicago, IL is during May-September.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
popular airports
Popular airports from Santa Ana, CA to Chicago, IL
Santa Ana
Chicago
The major airport for departures in Santa Ana is John Wayne Airport. Find all the information you need to know about services, amenities and connections at John Wayne Airport for your trip from Santa Ana to Chicago.
Amenities at airport
Wifi
Shopping
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Shower
Lounge
Lost and Found Office
Car Rentalinformation
Distance to city center
3 km
Car connection
I-405, exit MacArthur BlvdWifi
- Free Wi-Fi available throughout the airport.
Shopping
- Shops available in terminals, include Hudson News and Sunglass Hut.
Parking
- Parking available near the terminal, approximately 1.9€ ($2) per hour.
Dining
- Located in terminals; options include fast food and sit-down restaurants like McDold's and Ruby's Diner
Taxis
- Available outside the terminal.
Accessibility
- Elevators, ramps
WC
- Available throughout the airport.
Hotel
- Hotels within walking distance, Hilton Irvine/Orange County Airport.
Shower
- No showers available.
Lounge
- Admirals Club in terminal A.
Lost and Found Office
- Available throughout the airport.
Car Rental
- Car rental services available on-site; companies include Alamo, Avis, and Hertz
Public transit options for John Wayne Airport
- Bus Route 76, John Wayne Airport-Upper Level, 14 km
The major airport for arrivals in Chicago is O'Hare International Airport. Find all the information you need to know about services, amenities and connections at O'Hare International Airport for your journey to Chicago from Santa Ana.
Amenities at airport
WifiShoppingParkingDiningATMTaxisAccessibilityWCHotelShowerLoungeLost and Found OfficeCar Rentalinformation
Distance to city center
3 kmCar connection
I-190, Exit 1Wifi
- Free Wi-Fi available throughout the airport.
Shopping
- Shops are located in all terminals, including duty-free and brands like Hudson and MAC Cosmetics.
Parking
- Parking available with options including hourly, daily, and economy lots, approximately 2.85€ ($3) per hour.
Dining
- Restaurants are located in all terminals, offering a variety of cuisines including American and intertiol. Top options include Tortas Frontera and Publican Tavern.
Taxis
- Available outside the terminal.
Accessibility
- Elevators, ramps, toilets
WC
- Available throughout the airport.
Hotel
- Hotels such as Hilton Chicago O'Hare are located on airport grounds, with others like the Hyatt Regency nearby.
Shower
- Showers are available in some lounges, such as the United Club, but access may require a fee or membership.
Lounge
- Lounges available, including United Club and American Airlines Admirals Club.
Lost and Found Office
- Lost and Found located in terminal 1, near the baggage claim area.
Car Rental
- Car rental services are available at the Multi-Modal Facility, with companies like Hertz and Avis.
Public transit options for O'Hare International Airport
- CTA Blue Line, O'Hare Station, 45 minutes to city center
More options for your journey from Santa Ana, CA to Chicago, IL
Here are some other resources that might have the information you need
Most popular flights to and from Chicago, IL and Santa Ana, CA
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