Travel Information
Compare bus, flight, and train for Charleston, SC to Indianapolis, IN
Omio recommends booking the flight as it is the most popular option from Charleston, SC to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from $134. For those with little time consider booking a flight which can get you there in 3h 3m. The ticket price range depends on the travel mode: a bus costs an average of $134, and a train costs an average of $331.
Distance: 594 miles (957 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
$373 Average price | $216 Average price | $191 Average price Cheapest |
33h 51m Average total duration 33h 21m Onboard + 30m Additional time* | 6h 3m Average total duration Fastest 3h 3m Onboard + 3h 0m Additional time* | 23h 55m Average total duration 23h 25m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Charleston, SC to Indianapolis, IN by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Charleston, SC to Indianapolis, IN
Trains from Charleston, SC to Indianapolis, IN run on average 1 times per day, taking around 33h 21m. Cheap train tickets for this journey start at $331 (€270) but you can travel from only $47 (€38) by flight.
The earliest train runs at 00:15, the last at 21:34. The fastest train covers the 594 miles (957 km) distance in 33h 21m.
Distance 594 miles (957 km) |
Average train duration 33h 21m |
Cheapest ticket price $331 (€270) |
Trains per day 1 |
Fastest train 33h 21m |
First train 12:15 AM |
Last train 9:34 PM |
FAQs: Trains from Charleston, SC to Indianapolis, IN
Find answers to the most common questions about traveling from Charleston, SC to Indianapolis, IN by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Charleston, SC to Indianapolis, IN
- 6:00 AM - 11:00 PM Monday - Sunday
- Free
- Parking is available a few blocks away from the station.
- Harry & Izzy's
- St. Elmo Steak House
- Outside the main entrance.
- Ramps.
- Free for passengers
- Crowne Plaza Indianapolis-Dwtn-Union-Stn
- Omni Severin Hotel
- The Westin Indianapolis
- Located in the main hall
- Free
- Hall 1: main entrance, platform for Amtrak's Cardinal line
- Bus: IndyGo routes available nearby
More options for your journey from Charleston, SC to Indianapolis, IN
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