The cheapest and fastest trains from Lyon to Brussels
Cheapest price
$146
Average price
$274
Fastest journey
3 h 56 m
Average duration
4 h 2 m
Trains per day
42
Distance
569 km
The best way to find a cheap train ticket from Lyon to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Brussels will cost around $274 if you buy it on the day, but the cheapest tickets can be found for only $146.
Of the 42 trains that leave Lyon for Brussels on Thu, Apr 02, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Apr 02 the direct trains cover the 569 km distance in an average of 4 h 2 m but if you time it right, some trains will get you there in just 3 h 56 m .
On Thu, Apr 02 the slowest trains will take 4 h 11 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
98548:27 AM3h59Lyon Part Dieu12:26 PMBrussels-Midi$1461One-way0 transfers
98685:00 PM3h56Lyon Part Dieu8:56 PMBrussels-Midi$1791One-way0 transfers
98645:00 PM3h56Lyon Part Dieu8:56 PMBrussels-Midi$1991One-way0 transfers
6694+
93591:04 PM4h13Lyon Part Dieu5:17 PMBrussels-Midi$2391One-way1 transfer
6618+
93591:04 PM4h13Lyon Part Dieu5:17 PMBrussels-Midi$2391One-way1 transfer
98685:00 PM3h56Lyon Part Dieu8:56 PMBrussels-Midi$1791One-way0 transfers
98645:00 PM3h56Lyon Part Dieu8:56 PMBrussels-Midi$1991One-way0 transfers
98548:27 AM3h59Lyon Part Dieu12:26 PMBrussels-Midi$1461One-way0 transfers
6902+
94237:07 AM4h10Lyon Saint-Exupéry TGV11:17 AMBrussels-Midi$3601One-way1 transfer
6642+
93216:38 AM4h11Lyon Part Dieu10:49 AMBrussels-Midi$3141One-way1 transfer
Travel Information
Compare train, bus, and flight for Lyon to Brussels
Omio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $23. For those with little time consider booking a flight which can get you there in 1h 54m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $23, and a flight costs an average of $119.
Distance: 353 miles (569 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$133 Average price | $51 Average price Cheapest | $276 Average price |
6h 8m Average total duration 5h 38m Onboard + 30m Additional time* | 8h 28m Average total duration 7h 58m Onboard + 30m Additional time* | 4h 54m Average total duration Fastest 1h 54m Onboard + 3h 0m Additional time* |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | 1.7 - 3.4kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Lyon to Brussels train times
The table below shows live departures for Lyon to Brussels trains for today, Wednesday, April 1. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
6908+ 9351 | 8:53 AM Lyon Saint-Exupéry TGV | 4h55 | 1:48 PM Brussels-Midi | 1 transfer | |
6908+ 9451 | 8:53 AM Lyon Saint-Exupéry TGV | 4h55 | 1:48 PM Brussels-Midi | 1 transfer | |
9862 | On time 9:00 AM Lyon Part Dieu | 4h26 | 1:26 PM Brussels-Midi | 0 transfersDirect | |
6616+ 9351 | 9:16 AM Gare de Lyon-Perrache | 4h32 | 1:48 PM Brussels-Midi | 1 transfer | |
6616+ 9451 | 9:16 AM Gare de Lyon-Perrache | 4h32 | 1:48 PM Brussels-Midi | 1 transfer | |
6616+ 9351 | 9:34 AM Lyon Part Dieu | 4h14 | 1:48 PM Brussels-Midi | 1 transfer | |
6616+ 9451 | 9:34 AM Lyon Part Dieu | 4h14 | 1:48 PM Brussels-Midi | 1 transfer | |
6618+ 9459 | 10:49 AM Gare de Lyon-Perrache | 4h28 | 3:17 PM Brussels-Midi | 1 transfer | |
6618+ 9359 | 10:49 AM Gare de Lyon-Perrache | 4h28 | 3:17 PM Brussels-Midi | 1 transfer | |
6694+ 9359 | 11:04 AM Lyon Part Dieu | 4h13 | 3:17 PM Brussels-Midi | 1 transfer | |
6618+ 9459 | 11:04 AM Lyon Part Dieu | 4h13 | 3:17 PM Brussels-Midi | 1 transfer | |
6618+ 9359 | 11:04 AM Lyon Part Dieu | 4h13 | 3:17 PM Brussels-Midi | 1 transfer | |
6694+ 9459 | 11:04 AM Lyon Part Dieu | 4h13 | 3:17 PM Brussels-Midi | 1 transfer | |
6910+ 9369 | 11:50 AM Lyon Saint-Exupéry TGV | 4h57 | 4:47 PM Brussels-Midi | 1 transfer | |
6620+ 9469 | 11:50 AM Gare de Lyon-Perrache | 4h57 | 4:47 PM Brussels-Midi | 1 transfer | |
6620+ 9369 | 11:50 AM Gare de Lyon-Perrache | 4h57 | 4:47 PM Brussels-Midi | 1 transfer | |
6910+ 9469 | 11:50 AM Lyon Saint-Exupéry TGV | 4h57 | 4:47 PM Brussels-Midi | 1 transfer | |
6620+ 9469 | 12:04 PM Lyon Part Dieu | 4h43 | 4:47 PM Brussels-Midi | 1 transfer | |
6620+ 9369 | 12:04 PM Lyon Part Dieu | 4h43 | 4:47 PM Brussels-Midi | 1 transfer | |
6622+ 9371 | 12:50 PM Gare de Lyon-Perrache | 4h27 | 5:17 PM Brussels-Midi | 1 transfer | |
6622+ 9471 | 12:50 PM Gare de Lyon-Perrache | 4h27 | 5:17 PM Brussels-Midi | 1 transfer | |
6622+ 9371 | 1:04 PM Lyon Part Dieu | 4h13 | 5:17 PM Brussels-Midi | 1 transfer | |
6622+ 9471 | 1:04 PM Lyon Part Dieu | 4h13 | 5:17 PM Brussels-Midi | 1 transfer | |
6624+ 9377 | 1:50 PM Gare de Lyon-Perrache | 4h32 | 6:22 PM Brussels-Midi | 1 transfer | |
6920+ 9377 | 1:54 PM Lyon Saint-Exupéry TGV | 4h28 | 6:22 PM Brussels-Midi | 1 transfer | |
6624+ 9377 | 2:04 PM Lyon Part Dieu | 4h18 | 6:22 PM Brussels-Midi | 1 transfer | |
6626+ 9387 | 2:50 PM Gare de Lyon-Perrache | 4h54 | 7:44 PM Brussels-Midi | 1 transfer | |
9868 | On time 3:00 PM Lyon Part Dieu | 3h56 | 6:56 PM Brussels-Midi | 0 transfersDirect | |
9864 | On time 3:00 PM Lyon Part Dieu | 3h56 | 6:56 PM Brussels-Midi | 0 transfersDirect | |
6696+ 9387 | 3:38 PM Lyon Part Dieu | 4h06 | 7:44 PM Brussels-Midi | 1 transfer | |
6628+ 9393 | 3:50 PM Gare de Lyon-Perrache | 4h57 | 8:47 PM Brussels-Midi | 1 transfer | |
6922+ 9393 | 3:54 PM Lyon Saint-Exupéry TGV | 4h53 | 8:47 PM Brussels-Midi | 1 transfer | |
6628+ 9393 | 4:04 PM Lyon Part Dieu | 4h43 | 8:47 PM Brussels-Midi | 1 transfer | |
| Thursday, April 2 | |||||
6642+ 9321 | 4:24 AM Gare de Lyon-Perrache | 4h25 | 8:49 AM Brussels-Midi | 1 transfer | |
6642+ 9321 | 4:38 AM Lyon Part Dieu | 4h11 | 8:49 AM Brussels-Midi | 1 transfer | |
6644+ 9423 | 4:38 AM Gare de Lyon-Perrache | 4h39 | 9:17 AM Brussels-Midi | 1 transfer | |
6690+ 9423 | 5:04 AM Lyon Part Dieu | 4h13 | 9:17 AM Brussels-Midi | 1 transfer | |
6604+ 9423 | 5:04 AM Lyon Part Dieu | 4h13 | 9:17 AM Brussels-Midi | 1 transfer | |
6902+ 9423 | 5:07 AM Lyon Saint-Exupéry TGV | 4h10 | 9:17 AM Brussels-Midi | 1 transfer | |
6608+ 9429 | 5:50 AM Gare de Lyon-Perrache | 4h27 | 10:17 AM Brussels-Midi | 1 transfer | |
6608+ 9329 | 5:50 AM Gare de Lyon-Perrache | 4h27 | 10:17 AM Brussels-Midi | 1 transfer | |
6906+ 9429 | 5:54 AM Lyon Saint-Exupéry TGV | 4h23 | 10:17 AM Brussels-Midi | 1 transfer | |
6906+ 9329 | 5:54 AM Lyon Saint-Exupéry TGV | 4h23 | 10:17 AM Brussels-Midi | 1 transfer | |
6608+ 9429 | 6:04 AM Lyon Part Dieu | 4h13 | 10:17 AM Brussels-Midi | 1 transfer | |
6608+ 9329 | 6:04 AM Lyon Part Dieu | 4h13 | 10:17 AM Brussels-Midi | 1 transfer | |
9854 | On time 6:27 AM Lyon Part Dieu | 3h59 | 10:26 AM Brussels-Midi | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 01
Apr 02
Apr 03
Apr 04
Apr 05
Apr 06
Apr 07
Apr 08
Apr 09
Apr 10
Apr 11
Apr 12
Apr 13
Apr 14
Apr 15
Apr 16
Apr 17
Apr 18
Apr 19
Apr 20
Apr 21
How far in advance should I book train tickets from Lyon to Brussels?
Journey information
Overview: Train from Lyon to Brussels
Trains from Lyon to Brussels run on average 4 times per day, taking around 5h 38m. Cheap train tickets for this journey start at $57 (€46) but you can travel from only $23 (€19) by bus.
There are 4 trains per day. The earliest train runs at 00:15, the last at 19:16. The fastest train covers the 353 miles (569 km) distance in 3h 43m.
Distance 353 miles (569 km) |
Average train duration 5h 38m |
Cheapest ticket price $57 (€46) |
Trains per day 4 |
Direct trains 4 |
Fastest train 3h 43m |
First train 12:15 AM |
Last train 7:16 PM |
Train companies: TGV, TGV INOUI from Lyon to Brussels trainsTGV, TGV INOUI trains will get you between Lyon and Brussels from $23 (€19). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
TGV
TGV INOUI
FAQs: Trains from Lyon to Brussels
Find answers to the most common questions about traveling from Lyon to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Lyon to Brussels
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Free unlimited WiFi.
- Luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk.
- Alto Café
- Paul
- Paul The Café
- Starbucks
- Exki
- Sushi Shop
- Carrefour
- Complimentary personalized care is available.
- Radisson Blu Hotel Lyon
- Mercure Lyon Center
- ibis Styles Lyon Center
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
- Located in the station's main hall.
- Metro lines: A, B, C, D
- Tram lines: T4, K240, T3, K100
- Bus lines: 2960, C2, C3, C6, C9
- Train lines: TGV, TGV Lyria, TGV INOUI, OUIGO, TER, Intercités, Eurostar, AVE
- Mon - Fri: 10:00 - 18:00
- Free, unlimited Wi-Fi is available after creating an account and connecting to "CONNECTION."
- PAUL
- Hearing, mobility, and visual disability assistance. Accessibility available with elevator, ramp or step-free access, barrier-free toilets.
- Mercure Lyon Centre Chateau Perrache
- Hotel De Normandie
- InterContinental Lyon-Hotel Dieu
- Mon - Fri: 10:00 - 18:00
- Information services are available at the ticket office, located in Hall Level 2.
- Metro lines: A, B, C, D
- Bus lines: 8, 31, 46, 49, 55, 60, 63, S1, C19, C21, C22
- Tram lines: 1, 2
- Train lines: TGV, TGV INOUI, OUIGO, TER Auvergne-Rhône-Alpes, Intercités
- 6:00 AM - 11:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week. Access is available via Rue de Grèce.
- Restaurant Moxy Lyon Airport
- NH Lyon Airport Restaurant
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €0.50
- Moxy Lyon Airport
- NH Lyon Airport
- Ibis Budget Aéroport Lyon Saint Exupéry
- Located in the main hall
- 150 places, covered
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform access
- Hall 2: ticket office and services
- Hall 3: connection to Lyon-Saint Exupéry Airport
- Tramway: Rhônexpress
- Bus: Several lines available
- Mon - Sun: 05:45 - 21:30
- Wi-Fi is available for a fee.
- Baggage storage facility is located across from the Thalys business lounge.
- Pullman Hotel Bar
- Quick Gare du Midi
- Subway
- EXKi Zuid
- Starbucks
- Häagen-Dazs
- Sbarro
- The Coffee Club
- The Belgian Chocolate House
- PAUL
- & many more
- Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
- Les Lofts De Styliste
- Park Inn by Radisson Brussels Midi
- Pullman Brussels Centre Midi
- Located in the main concourse and next to the international platforms.
More options for your journey from Lyon to Brussels
Here are some other resources that might have the information you need



