Travel Information
Compare bus and flight for Rome to Santander
Omio recommends booking the flight as it is the most popular option from Rome to Santander among Omio's users. If you are prioritising price take the bus with prices starting from €85. For those with little time consider booking a flight which can get you there in 3h 2m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.3 - 3.4kg. The ticket price range depends on the travel mode: a bus costs an average of €85, and a flight costs an average of €25.
Distance: 833 miles (1341 km)
Compare flight with
Most popular Flight | Bus |
|---|---|
€179 Average price | €143 Average price Cheapest |
6h 2m Average total duration Fastest 3h 2m Onboard + 3h 0m Additional time* | 38h 24m Average total duration 37h 54m Onboard + 30m Additional time* |
4.0 - 8.0kg CO2 emissions | 1.3 - 3.4kg CO2 emissions Lowest |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare prices and tickets Rome to Santander by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Rome to Santander trains with Omio?
operates all train services from Rome to Santander. Omio is the only official third party seller for tickets.
Why book with Omio vs ?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Rome to Santander.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: tickets can only be bought on Omio or 's website as Omio is the only official third party seller for tickets. Trainline, RailEurope, and Rail.Ninja do not sell tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Rome to Santander.
Journey information
Overview: Train from Rome to Santander
Take a train from Rome to Santander and enjoy the approximately 833 miles (1341 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 03:00, the last at 15:05.
Distance 833 miles (1341 km) |
First train 03:00 |
Last train 15:05 |
FAQs: Trains from Rome to Santander
Find answers to the most common questions about traveling from Rome to Santander by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Santander, this guide helps you travel smarter and with confidence.

More options for your journey from Rome to Santander
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