Travel Information
Compare train, bus, and flight for St. Louis, MO to Roanoke, VA
Omio recommends booking the train as it is the most popular option from St. Louis, MO to Roanoke, VA among Omio's users. If you are prioritising price take the bus with prices starting from $146. For those with little time consider booking a flight which can get you there in 4h 58m. The ticket price range depends on the travel mode: a bus costs an average of $146, and a flight costs an average of $380.
Distance: 566 miles (911 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$237 Average price | $170 Average price Cheapest | $394 Average price |
28h 49m Average total duration 28h 19m Onboard + 30m Additional time* | 20h 30m Average total duration 20h 0m Onboard + 30m Additional time* | 7h 58m Average total duration Fastest 4h 58m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets St. Louis, MO to Roanoke, VA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from St. Louis, MO to Roanoke, VA
Trains from St. Louis, MO to Roanoke, VA run on average 2 times per day, taking around 28h 19m. Cheap train tickets for this journey start at $223 (€182) but you can travel from only $146 (€118) by bus.
The earliest train runs at 06:15, the last at 08:56. The fastest train covers the 566 miles (911 km) distance in 37h 3m.
Distance 566 miles (911 km) |
Average train duration 28h 19m |
Cheapest ticket price $223 (€182) |
Trains per day 2 |
Fastest train 37h 3m |
First train 6:15 AM |
Last train 8:56 AM |
Train companies: Amtrak from St. Louis, MO to Roanoke, VA trainsAmtrak trains will get you between St. Louis, MO and Roanoke, VA from $146 (€118). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from St. Louis, MO to Roanoke, VA
Find answers to the most common questions about traveling from St. Louis, MO to Roanoke, VA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Roanoke, VA, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from St. Louis, MO to Roanoke, VA
- 5:30 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available on-site with both short-term and long-term options.
- Landry's Seafood House
- The Station Grille
- Outside the main entrance.
- Ramps, restrooms.
- $1
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Courtyard St. Louis Downtown West
- Drury Inn St. Louis at Union Station
- Located in the main hall
- Avis
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for Amtrak and regional trains
- Hall 2: MetroLink connections
- MetroLink: Red Line, Blue Line
- Bus: Several lines available including 40, 94, 97
- 6:00 AM - 10:00 PM Monday - Sunday
- Outside the station.
- Ramps.
- Hotel Roanoke & Conference Center
- Hampton Inn & Suites Roanoke-Downtown
- Cambria Hotel Downtown Roanoke
- Located near the platform
- The station consists of a single platform serving Amtrak's Northeast Regional line.
- Bus: Thruway bus connections available between Roanoke and Virginia Tech and Blacksburg
Most popular train connections from St. Louis, MO
More options for your journey from St. Louis, MO to Roanoke, VA
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