Travel Information
Compare bus, train, and flight for Heidelberg to Prague
Omio recommends booking the bus as it is the most popular option from Heidelberg to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a flight which can get you there in 1h 22m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $24, and a flight costs an average of $163.
Distance: 259 miles (418 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$44 Average price Cheapest | $80 Average price | $203 Average price |
7h 3m Average total duration 6h 33m Onboard + 30m Additional time* | 9h 10m Average total duration 8h 40m Onboard + 30m Additional time* | 4h 22m Average total duration Fastest 1h 22m Onboard + 3h 0m Additional time* |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.3 - 2.5kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Heidelberg to Prague
How to get from Heidelberg to Prague by train, bus or flight.
Our recommendation
The best way to travel from Heidelberg to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus5:50 AM6h55Heidelberg, Hauptbahnhof12:45 PMPraha, Na Knížecí$691One-way0 transfers
Cheapest
439п6:30 PM13h20Heidelberg, Alte Eppelheimer Straße (Hbf)7:50 AMPraha, ÚAN Florenc$631One-way0 transfers
Fastest
DE440910:00 AM1h00Frankfurt am Main Airport11:00 AMPrague Vaclav Havel Airport$2641One-way0 transfers
Other options
ICE 1648 · 88617 · 3569+
3599:36 AM8h45Heidelberg Hbf6:21 PMPrague hlavní nádraží$751One-way3 transfers
ICE 219 · 88619 · 3573+
36112:06 PM8h15Heidelberg Hbf8:21 PMPrague hlavní nádraží$1121One-way3 transfers
ICE 117+
3599:13 AM9h08Heidelberg Hbf6:21 PMPrague hlavní nádraží$2091One-way1 transfer
FlixBus5:50 AM7h15Heidelberg, Hauptbahnhof1:05 PMPraha, ÚAN Florenc$691One-way0 transfers
FlixBus4:05 PM6h50Heidelberg, Hauptbahnhof10:55 PMPraha, Na Knížecí$801One-way0 transfers
FlixBus4:05 PM7h05Heidelberg, Hauptbahnhof11:10 PMPraha, ÚAN Florenc$801One-way0 transfers
DE44073:00 PM1h00Frankfurt am Main Airport4:00 PMPrague Vaclav Havel Airport$2641One-way0 transfers
LO372 · LO52110:50 AM6h35Stuttgart Airport5:25 PMPrague Vaclav Havel Airport$2541One-way1 transfer
S1 · ICE 2614+
DE44077:03 AM8h57Heidelberg Hbf4:00 PMPrague Vaclav Havel Airport$2701One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Heidelberg to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Heidelberg to Prague.

This is compared to other travel options from Heidelberg to Prague:
A bus is $15 (€12) less than a train for this route with tickets for a train from Heidelberg to Prague costing on average $39 (€32).
A bus is $139 (€113) less than a flight for this route with tickets for a flight from Heidelberg to Prague costing on average $163 (€133).
Other travel options to Prague take longer:
Bus takes on average 6h 40m.
Train takes on average 8h 13m.
- Around 55 flights per day.
- Around 9 trains per day.
- Around 7 buses per day.
However, we recommend checking specific travel dates for your route between Heidelberg and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Heidelberg Hbf and arrive in Prague hlavní nádraží.
- Buses mostly depart from Heidelberg, Hauptbahnhof and arrive in Praha, ÚAN Florenc.
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar to go to Prague by bus.
- Travel with alex-Länderbahn und Vogtlandbahn-GmbH, Deutsche Bahn to go to Prague by train.
- Travel with Lufthansa, Condor Flugdienst, Swiss to go to Prague by flight.
- 5 direct buses per day with FlixBus, BlaBlaCar.
- 7 direct flights per day with Lufthansa.
Travelling from Heidelberg to Prague: related information
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