Travel Information
Compare train, bus, and flight for Luxembourg to Prague
Omio recommends booking the bus as it is the most popular option from Luxembourg to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $45. For those with little time consider booking a flight which can get you there in 2h 13m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $45, and a flight costs an average of $103.
Distance: 370 miles (596 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
$70 Average price Cheapest | $261 Average price | $132 Average price |
11h 22m Average total duration 10h 52m Onboard + 30m Additional time* | 5h 13m Average total duration Fastest 2h 13m Onboard + 3h 0m Additional time* | 11h 36m Average total duration 11h 6m Onboard + 30m Additional time* |
0.6 - 1.5kg CO2 emissions | 1.8 - 3.6kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Luxembourg to Prague
How to get from Luxembourg to Prague by train, bus or flight.
Our recommendation
The best way to travel from Luxembourg to Prague is by taking a bus because it’s the best combination of price and speed.
(London -> Prague)9:30 PM8h50Luxembourg, P+R Bouillon6:20 AMPrague, Central Train Station$851One-way0 transfers
Cheapest
(London -> Prague)9:30 PM8h50Luxembourg, P+R Bouillon6:20 AMPrague, Central Train Station$851One-way0 transfers
Fastest
LH5643+
LH14002:30 PM3h00Luxembourg Airport5:30 PMPrague Vaclav Havel Airport$5981One-way1 transfer
Other options
RE 5113 · ICE 29 · 3597+
3639:33 AM12h49Luxembourg station10:22 PMPrague hlavní nádraží$2141One-way3 transfers
Bus 82130 · 29523 · ICE 2517 · S11:15 PM19h55Luxembourg station9:10 AMPrague hlavní nádraží$1991One-way5 transfers
RE 5113 · ICE 29 · R 3575 · EC 3639:33 AM12h49Luxembourg station10:22 PMPrague hlavní nádraží$2721One-way3 transfers
(London -> Prague)9:30 PM8h55Luxembourg, P+R Bouillon6:25 AMPraha, ÚAN Florenc$851One-way0 transfers
FlixBus · FlixBus2:05 AM15h25Luxembourg, P+R Bouillon5:30 PMPrague, Central Train Station$1091One-way1 transfer
FlixBus · FlixBus2:40 AM14h55Luxembourg, P+R Bouillon5:35 PMPraha, M. Horákové (Hradčanská)$1121One-way1 transfer
KL1710+
KL135510:25 AM3h20Luxembourg Airport1:45 PMPrague Vaclav Havel Airport$3371One-way1 transfer
KL1712 · KL13592:35 PM5h10Luxembourg Airport7:45 PMPrague Vaclav Havel Airport$3201One-way1 transfer
KL1710+
KL135710:25 AM7h15Luxembourg Airport5:40 PMPrague Vaclav Havel Airport$3371One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Luxembourg to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Luxembourg to Prague.

This is compared to other travel options from Luxembourg to Prague:
A bus is $31 (€25) less than a train for this route with tickets for a train from Luxembourg to Prague costing on average $77 (€62).
A bus is $57 (€46) less than a flight for this route with tickets for a flight from Luxembourg to Prague costing on average $103 (€83).
Other travel options to Prague take longer:
Bus takes on average 8h 50m.
Train takes on average 11h 10m.
- Around 36 flights per day.
- Around 16 buses per day.
- Around 6 trains per day.
However, we recommend checking specific travel dates for your route between Luxembourg and Prague as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Luxembourg Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Luxembourg station and arrive in Prague hlavní nádraží.
- Buses mostly depart from Luxembourg, P+R Bouillon and arrive in Praha, ÚAN Florenc.
- Travel with FlixBus, BlaBlaCar Bus to go to Prague by bus.
- Travel with Luxair, KLM Cityhopper, KLM, Lufthansa, Lufthansa Cityline, Air Baltic, Swiss, Air Dolomiti, Buzz, Helvetic Airways to go to Prague by flight.
- Travel with Deutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH, Süwex, Luxembourg Railways (CFL) to go to Prague by train.
Travelling from Luxembourg to Prague: related information
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