Travel Information
Compare train, bus, and flight for Mannheim to Milan
Omio recommends booking the train as it is the most popular option from Mannheim to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a flight which can get you there in 1h 17m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $24, and a train costs an average of $83.
Distance: 280 miles (452 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$197 Average price | $61 Average price Cheapest | $119 Average price |
7h 19m Average total duration 6h 49m Onboard + 30m Additional time* | 11h 55m Average total duration 11h 25m Onboard + 30m Additional time* | 4h 17m Average total duration Fastest 1h 17m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.1kg CO2 emissions | 1.4 - 2.7kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Mannheim to Milan
How to get from Mannheim to Milan by train, bus or flight.
Our recommendation
The best way to travel from Mannheim to Milan is by taking a bus because it’s the best combination of price and speed.
FlixBus8:30 AM8h20Mannheim, ZOB (Heinrich-Von-Stephan-Straße)4:50 PMMilano, Autostazione Lampugnano$881One-way0 transfers
Cheapest
FlixBus8:30 AM8h20Mannheim, ZOB (Heinrich-Von-Stephan-Straße)4:50 PMMilano, Autostazione Lampugnano$881One-way0 transfers
Fastest
U254049:15 AM1h10Frankfurt am Main Airport10:25 AMMilan Linate Airport$1621One-way0 transfers
Other options
FlixBus9:40 PM9h30Mannheim, ZOB (Heinrich-Von-Stephan-Straße)7:10 AMMilano, Autostazione Lampugnano$921One-way0 transfers
FlixBus7:00 PM10h05Mannheim, ZOB (Heinrich-Von-Stephan-Straße)5:05 AMMilano, Autostazione Lampugnano$921One-way0 transfers
FlixBus10:35 PM9h30Mannheim, ZOB (Heinrich-Von-Stephan-Straße)8:05 AMMilano, Autostazione Lampugnano$971One-way0 transfers
ICE 2610+
U2542811:33 AM6h42Mannheim Hbf6:15 PMMilan Linate Airport$1721One-way1 transfer
TGV 9511+
4258+
U2542812:21 PM5h54Mannheim Hbf6:15 PMMilan Linate Airport$1741One-way2 transfers
ICE 1010+
U2542811:07 AM7h08Mannheim Hbf6:15 PMMilan Linate Airport$1781One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Mannheim to Milan
Travel to Milan easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mannheim to Milan.

This is compared to other travel options from Mannheim to Milan:
A flight is $3 (€3) less than a bus for this route with tickets for a bus from Mannheim to Milan costing on average $24 (€20).
A flight is $62 (€50) less than a train for this route with tickets for a train from Mannheim to Milan costing on average $83 (€67).
Other travel options to Milan take longer:
Train takes on average 7h 4m.
Bus takes on average 8h 20m.
- Around 84 flights per day.
- Around 6 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Mannheim and Milan as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Milan Malpensa Airport.
- Trains mostly depart from Mannheim Hbf and arrive in Milan Centrale.
- Buses mostly depart from Mannheim, ZOB (Heinrich-Von-Stephan-Straße) and arrive in Milano, Autostazione Lampugnano.
- Travel with FlixBus, BlaBlaCar Bus, Marino Autolinee to go to Milan by bus.
- Travel with Malta Air, easyJet, ITA, Lufthansa, Air Dolomiti, Eurowings, Ryanair to go to Milan by flight.
- Travel with Deutsche Bahn, Trenitalia to go to Milan by train.
- 5 direct buses per day with FlixBus, BlaBlaCar Bus.
- 28 direct flights per day with Malta Air, ITA.
Travelling from Mannheim to Milan: related information
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