Travel Information
Compare train, bus, and flight for Osnabrück to Prague
Omio recommends booking the bus as it is the most popular option from Osnabrück to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $32. For those with little time consider booking a flight which can get you there in 1h 29m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $32, and a flight costs an average of $65.
Distance: 314 miles (506 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$56 Average price Cheapest | $92 Average price | $168 Average price |
10h 43m Average total duration 10h 13m Onboard + 30m Additional time* | 8h 29m Average total duration 7h 59m Onboard + 30m Additional time* | 4h 29m Average total duration Fastest 1h 29m Onboard + 3h 0m Additional time* |
0.5 - 1.3kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.5 - 3.0kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Osnabrück to Prague
How to get from Osnabrück to Prague by train, bus or flight.
Our recommendation
The best way to travel from Osnabrück to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus8:25 AM10h15Osnabrück, Hauptbahnhof6:40 PMPraha, ÚAN Florenc$591One-way0 transfers
Cheapest
FlixBus8:25 AM10h15Osnabrück, Hauptbahnhof6:40 PMPraha, ÚAN Florenc$591One-way0 transfers
Fastest
EW97706:35 AM1h15Dusseldorf Airport7:50 AMPrague Vaclav Havel Airport$1361One-way0 transfers
Other options
FlixTrain · FlixTrain+
FlixBus11:15 AM10h25Osnabrück Hbf9:40 PMPraha, ÚAN Florenc$751One-way2 transfers
FlixTrain · FlixTrain+
FlixBus11:15 AM12h40Osnabrück Hbf11:55 PMPrague, Central Train Station$751One-way2 transfers
FlixTrain · FlixTrain+
FlixBus11:15 AM12h40Osnabrück, Hauptbahnhof11:55 PMPrague, Central Train Station$751One-way2 transfers
FlixBus8:55 PM10h15Osnabrück, Hauptbahnhof7:10 AMPraha, ÚAN Florenc$611One-way0 transfers
FlixBus · FlixBus8:55 PM14h35Osnabrück, Hauptbahnhof11:30 AMPrague, Central Train Station$661One-way1 transfer
FlixBus · FlixBus1:30 AM10h50Osnabrück, Hauptbahnhof12:20 PMPraha, ÚAN Florenc$741One-way1 transfer
EW42037:15 PM1h15Dusseldorf Airport8:30 PMPrague Vaclav Havel Airport$1961One-way0 transfers
QS80416:35 AM1h15Dusseldorf Airport7:50 AMPrague Vaclav Havel Airport$2211One-way0 transfers
LO406 · LO5277:15 AM4h50Dusseldorf Airport12:05 PMPrague Vaclav Havel Airport$3411One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Osnabrück to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Osnabrück to Prague.

This is compared to other travel options from Osnabrück to Prague:
A bus is $2 (€2) less than a train for this route with tickets for a train from Osnabrück to Prague costing on average $34 (€27).
A bus is $34 (€27) less than a flight for this route with tickets for a flight from Osnabrück to Prague costing on average $65 (€52).
Other travel options to Prague take longer:
Train takes on average 7h 32m.
Bus takes on average 10h 15m.
- Around 42 flights per day.
- Around 10 trains per day.
- Around 10 buses per day.
However, we recommend checking specific travel dates for your route between Osnabrück and Prague as scheduled services by train, bus, and flight can vary by season or day of the week.
- Trains mostly depart from Osnabrück Hbf and arrive in Prague hlavní nádraží.
- Flights mostly depart from Dusseldorf Airport and arrive in Prague Vaclav Havel Airport.
- Buses mostly depart from Osnabrück, Hauptbahnhof and arrive in Prague, Central Train Station.
- Travel with Eurowings, Lufthansa, Air Baltic to go to Prague by flight.
- Travel with Deutsche Bahn, Intercity to go to Prague by train.
- Travel with FlixBus to go to Prague by bus.
- 2 direct flights per day with Air Baltic.
- 2 direct buses per day with FlixBus.
Travelling from Osnabrück to Prague: related information
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