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Compare train, bus, and flight for Prague to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Prague to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from $28. For those with little time consider booking a flight which can get you there in 2h 33m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $28, and a flight costs an average of $134.
Distance: 254 miles (409 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$101 Average price | $47 Average price Cheapest | $194 Average price |
6h 46m Average total duration 6h 16m Onboard + 30m Additional time* | 7h 46m Average total duration 7h 16m Onboard + 30m Additional time* | 5h 33m Average total duration Fastest 2h 33m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | 1.2 - 2.5kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Prague to Frankfurt am Main
How to get from Prague to Frankfurt am Main by train, bus or flight.
Our recommendation
The best way to travel from Prague to Frankfurt am Main is by taking a bus because it’s the best combination of price and speed.
FlixBus10:55AM8h00Praha, Na Knížecí06:55PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$751One-way0 transfers
Cheapest
FlixBus04:10AM7h10Praha, Na Knížecí11:20AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$701One-way0 transfers
Fastest
DE440808:50AM1h00Prague Vaclav Havel Airport09:50AMFrankfurt am Main Airport$1841One-way0 transfers
Other options
EX 358 · 3568 · ICE 62409:35AM7h27Prague hlavní nádraží05:02PMFrankfurt (Main) Hbf$1941One-way2 transfers
EX 358 · 3568 · ICE 62409:35AM7h44Prague hlavní nádraží05:19PMFrankfurt Airport long-distance station$1941One-way2 transfers
EX 356 · 3572 · ICE 62011:35AM7h27Prague hlavní nádraží07:02PMFrankfurt (Main) Hbf$1941One-way2 transfers
FlixBus10:55AM8h30Praha, Na Knížecí07:25PMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$741One-way0 transfers
FlixBus10:30AM8h25Praha, ÚAN Florenc06:55PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$751One-way0 transfers
FlixBus10:30AM8h55Praha, ÚAN Florenc07:25PMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$741One-way0 transfers
DE440605:00PM1h00Prague Vaclav Havel Airport06:00PMFrankfurt am Main Airport$2061One-way0 transfers
DE441012:00PM1h00Prague Vaclav Havel Airport01:00PMFrankfurt am Main Airport$2281One-way0 transfers
LH139309:10AM1h10Prague Vaclav Havel Airport10:20AMFrankfurt am Main Airport$3521One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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How to get from Prague to Frankfurt am Main
The Best Way According to our Users
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FAQs: Travel from Prague to Frankfurt am Main
Travel to Frankfurt am Main easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Frankfurt am Main.

This is compared to other travel options from Prague to Frankfurt am Main:
A bus is $14 (€12) less than a train for this route with tickets for a train from Prague to Frankfurt am Main costing on average $43 (€34).
A bus is $106 (€86) less than a flight for this route with tickets for a flight from Prague to Frankfurt am Main costing on average $134 (€109).
Other travel options to Frankfurt am Main take longer:
Train takes on average 7h 3m.
Bus takes on average 6h 25m.
- Around 48 flights per day.
- Around 30 buses per day.
- Around 15 trains per day.
However, we recommend checking specific travel dates for your route between Prague and Frankfurt am Main as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Frankfurt (Main) Hbf.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
- Travel with Lufthansa, Air Dolomiti, Lot Polish Airlines, Condor Flugdienst, KLM, Austrian Airlines, Lufthansa Cityline, KLM Cityhopper, Eurowings, Helvetic Airways to go to Frankfurt am Main by flight.
- Travel with FlixBus, BlaBlaCar Bus, Infobus, BlaBlaCar to go to Frankfurt am Main by bus.
- Travel with Deutsche Bahn, České dráhy, ÖBB | Euro City (EC) to go to Frankfurt am Main by train.
- 7 direct flights per day with Lufthansa, Air Dolomiti, Condor Flugdienst, Lufthansa Cityline.
- 14 direct buses per day with FlixBus, BlaBlaCar Bus, BlaBlaCar.
- 0 direct trains per day with ÖBB | Euro City (EC).
Travelling from Prague to Frankfurt am Main: related information
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