Travel Information
Compare train and bus for Rome to Karlsruhe
Omio recommends booking the bus as it is the most popular option from Rome to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from $54. For those with little time consider booking a train which can get you there in 9h 39m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of $54, and a train costs an average of $279.
Distance: 529 miles (852 km)
Compare bus with
Most popular Bus | Train |
|---|---|
$85 Average price Cheapest | $279 Average price |
18h 10m Average total duration 17h 40m Onboard + 30m Additional time* | 10h 9m Average total duration Fastest 9h 39m Onboard + 30m Additional time* |
0.9 - 2.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Rome to Karlsruhe
How to get from Rome to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Rome to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBus04:35PM18h35Roma, Autostazione Tiburtina11:10AMKarlsruhe Hbf$1011One-way0 transfers
Cheapest
FlixBus · FlixBus10:10AM17h35Roma, Autostazione Tiburtina03:45AMKarlsruhe Hbf$941One-way1 transfer
Fastest
LH237+
ICE 20506:35PM4h24Rome Leonardo da Vinci Fiumicino Airport10:59PMKarlsruhe Hbf$4051One-way1 transfer
Other options
FlixBus · FlixBus · FlixBus05:25PM18h45Roma, Autostazione (Metro Anagnina)12:10PMKarlsruhe Hbf$951One-way2 transfers
FlixBus · FlixBus10:55PM20h40Roma, Autostazione Tiburtina07:35PMKarlsruhe Hbf$951One-way1 transfer
FlixBus · FlixBus12:10PM20h10Roma, Autostazione Tiburtina08:20AMKarlsruhe Hbf$1141One-way1 transfer
FR 7197+
FR 518508:40AM6h55Rome Leonardo da Vinci Fiumicino Airport03:35PMKarlsruhe/Baden-Baden Airport$1771One-way1 transfer
U22994+
ICE 20506:25PM4h34Rome Leonardo da Vinci Fiumicino Airport10:59PMKarlsruhe Hbf$1911One-way1 transfer
U22992+
ICE 20501:00PM9h59Rome Leonardo da Vinci Fiumicino Airport10:59PMKarlsruhe Hbf$2221One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Rome to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Rome to Karlsruhe.

This is compared to other travel options from Rome to Karlsruhe:
A bus is $225 (€182) less than a train for this route with tickets for a train from Rome to Karlsruhe costing on average $279 (€226).
Other travel options to Karlsruhe take longer:
Bus takes on average 17h 35m.
- Around 13 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Rome and Karlsruhe as scheduled services by train and bus can vary by season or day of the week.
- Buses mostly depart from Roma, Autostazione Tiburtina and arrive in Karlsruhe Hbf.
- Travel with Frecciarossa to go to Karlsruhe by train.
- Travel with FlixBus, Marino Autolinee to go to Karlsruhe by bus.
- 1 direct buses per day with FlixBus.
Travelling from Rome to Karlsruhe: related information
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