Travel Information
Compare bus and flight for Santander to Rome
Omio recommends booking the flight as it is the most popular option from Santander to Rome among Omio's users. If you are prioritising price take the flight with prices starting from $60. For those with little time consider booking a flight which can get you there in 2h 50m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.3 - 3.4kg. The ticket price range depends on the travel mode: a flight costs an average of $60, and a bus costs an average of $112.
Distance: 833 miles (1341 km)
Compare flight with
Most popular Flight | Bus |
|---|---|
$183 Average price Cheapest | $205 Average price |
5h 50m Average total duration Fastest 2h 50m Onboard + 3h 0m Additional time* | 34h 25m Average total duration 33h 55m Onboard + 30m Additional time* |
4.0 - 8.0kg CO2 emissions | 1.3 - 3.4kg CO2 emissions Lowest |
![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Santander to Rome
How to get from Santander to Rome by train, bus or flight.
Our recommendation
The best way to travel from Santander to Rome is by taking a flight because it’s the best combination of price and speed.
IB1060 · IB65310:05 AM8h10Santander Airport6:15 PMRome Leonardo da Vinci Fiumicino Airport$3751One-way1 transfer
Cheapest
VY1597 · VY61006:40 PM13h40Santander Airport8:20 AMRome Leonardo da Vinci Fiumicino Airport$3541One-way1 transfer
Fastest
VY1591 · VY61089:05 AM3h55Santander Airport1:00 PMRome Leonardo da Vinci Fiumicino Airport$4811One-way1 transfer
Other options
FlixBus · FlixBus · FlixBus6:50 PM39h10Santander, Estación de Autobuses10:00 AMRoma, Autostazione Tiburtina$3561One-way2 transfers
FlixBus · FlixBus · FlixBus · FlixBus9:25 AM56h40Santander, Estación de Autobuses6:05 PMRoma, Autostazione (Metro Anagnina)$3711One-way3 transfers
IB1060 · IB65110:05 AM5h20Santander Airport3:25 PMRome Leonardo da Vinci Fiumicino Airport$3991One-way1 transfer
IB1066 · IB6476:30 AM4h40Santander Airport11:10 AMRome Leonardo da Vinci Fiumicino Airport$3991One-way1 transfer
IB1066 · IB6516:30 AM8h55Santander Airport3:25 PMRome Leonardo da Vinci Fiumicino Airport$3991One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Santander to Rome
Travel to Rome easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Santander to Rome.

This is compared to other travel options from Santander to Rome:
A flight is $52 (€42) less than a bus for this route with tickets for a bus from Santander to Rome costing on average $112 (€91).
Other travel options to Rome take longer:
Bus takes on average 35h 15m.
- Around 13 flights per day.
- Around 2 buses per day.
However, we recommend checking specific travel dates for your route between Santander and Rome as scheduled services by bus and flight can vary by season or day of the week.
- Flights mostly depart from Santander Airport and arrive in Rome Leonardo da Vinci Fiumicino Airport.
- Buses mostly depart from Santander, Estación de Autobuses and arrive in Roma, Autostazione Tiburtina.
- Travel with Ryanair, Malta Air, Vueling Airlines, Iberia to go to Rome by flight.
- Travel with FlixBus, Alsa to go to Rome by bus.
- 0 direct flights per day with Malta Air.
Travelling from Santander to Rome: related information
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