Travel Information
Compare bus, train, and flight for Siena to Milan
Omio recommends booking the bus as it is the most popular option from Siena to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $10. For those with little time consider booking a train which can get you there in 4h 1m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $10, and a train costs an average of $32.
Distance: 182 miles (293 km)
Compare bus with
Most popular Bus | Train |
|---|---|
$20 Average price Cheapest | $44 Average price |
6h 23m Average total duration 5h 53m Onboard + 30m Additional time* | 4h 31m Average total duration Fastest 4h 1m Onboard + 30m Additional time* |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Siena to Milan
How to get from Siena to Milan by train, bus or flight.
Our recommendation
The best way to travel from Siena to Milan is by taking a bus because it’s the best combination of price and speed.
FlixBus12:15 PM5h40Siena, Stazione FS (Piazzale Carlo Rosselli)5:55 PMMilano, Autostazione Lampugnano$191One-way0 transfers
Cheapest
FlixBus3:05 PM6h35Siena, Stazione FS (Piazzale Carlo Rosselli)9:40 PMMilano, Autostazione Lampugnano$171One-way0 transfers
Fastest
Regionale 18278+
FRECCIAROSSA 95208:48 AM4h02Siena station12:50 PMMilan Centrale$881One-way1 transfer
Other options
Regionale 18208 · Regionale 17816 · Regionale Veloce TTPER 24706:36 AM8h13Siena station2:49 PMMilan Centrale$401One-way2 transfers
Regionale Veloce 4010+
Intercity 5806:25 AM5h50Siena station12:15 PMMilan Centrale$591One-way1 transfer
Regionale 19044 · ETRUSCHI LINE 18307 · Regionale 22964:41 PM6h45Siena station11:26 PMMilan Centrale$401One-way2 transfers
FlixBus2:51 PM6h49Siena, Siena/Viale Pietro Toselli9:40 PMMilano, Autostazione Lampugnano$171One-way0 transfers
FlixBus6:40 PM5h19Siena, Stazione FS (Piazzale Carlo Rosselli)11:59 PMMilano, Autostazione Lampugnano$171One-way0 transfers
FlixBus6:10 AM5h50Siena, Stazione FS (Piazzale Carlo Rosselli)12:00 PMMilano, San Donato - Settore B (Viale Giuseppe Impastato)$311One-way0 transfers
FlixBus+
AZ205810:55 AM11h15Siena, Siena/Viale Pietro Toselli10:10 PMMilan Linate Airport$1131One-way1 transfer
FlixBus+
AZ205810:45 AM11h25Siena, Stazione FS (Piazzale Carlo Rosselli)10:10 PMMilan Linate Airport$1131One-way1 transfer
FlixBus+
AZ205810:35 AM11h35Siena, P.za Gramsc10:10 PMMilan Linate Airport$1131One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Siena to Milan
Travel to Milan easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Siena to Milan.

This is compared to other travel options from Siena to Milan:
A bus is $22 (€18) less than a train for this route with tickets for a train from Siena to Milan costing on average $32 (€26).
A bus is $116 (€95) less than a flight for this route with tickets for a flight from Siena to Milan costing on average $126 (€103).
Other travel options to Milan take longer:
Bus takes on average 4h 50m.
Flight takes on average 6h 5m.
- Around 31 trains per day.
- Around 26 buses per day.
- Around 15 flights per day.
However, we recommend checking specific travel dates for your route between Siena and Milan as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Florence Peretola Airport and arrive in Milan Malpensa Airport.
- Trains mostly depart from Siena station and arrive in Milan Centrale.
- Buses mostly depart from Siena, Stazione FS (Piazzale Carlo Rosselli) and arrive in Milano, Autostazione Lampugnano.
- Travel with Italo, Frecciarossa, Regionale, Intercity to go to Milan by train.
- Travel with FlixBus, Itabus, BlaBlaCar, Curcio Viaggi to go to Milan by bus.
- 17 direct buses per day with FlixBus, Itabus, BlaBlaCar.
Travelling from Siena to Milan: related information
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