The cheapest and fastest buses from Frankfurt am Main to Lyon
Cheapest price
$81
Average price
$138
Fastest journey
7 h 10 m
Average duration
8 h 26 m
Buses per day
15
Distance
563 km
The best way to find a cheap bus ticket from Frankfurt am Main to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Lyon will cost around $138 if you buy it on the day, but the cheapest tickets can be found for only $81.
Of the 15 buses that leave Frankfurt am Main for Lyon on Thu, Apr 02, 9 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Apr 02 the direct buses cover the 563 km distance in an average of 8 h 26 m but if you time it right, some buses will get you there in just 7 h 10 m .
On Thu, Apr 02 the slowest buses will take 10 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4:00 AM7h10Frankfurt am Main11:10 AMLyon$811One-way0 transfers
7:00 AM7h30Frankfurt am Main2:30 PMLyon$881One-way0 transfers
7:30 AM7h40Frankfurt am Main3:10 PMLyon$901One-way0 transfers
07:35 AM10h10Frankfurt am Main, Hauptbahnhof5:45 PMLyon, Gare Perrache$991One-way0 transfers
FlixBus · FlixBus11:20 AM11h55Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)11:15 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1011One-way1 transfer
4:00 AM7h10Frankfurt am Main11:10 AMLyon$811One-way0 transfers
7:00 AM7h30Frankfurt am Main2:30 PMLyon$881One-way0 transfers
7:30 AM7h40Frankfurt am Main3:10 PMLyon$901One-way0 transfers
FlixBus7:05 PM9h40Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)4:45 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1871One-way0 transfers
07:35 AM10h10Frankfurt am Main, Hauptbahnhof5:45 PMLyon, Gare Perrache$991One-way0 transfers
Travel Information
Compare train, bus, and flight for Frankfurt am Main to Lyon
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $37. For those with little time consider booking a flight which can get you there in 1h 51m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $37, and a flight costs an average of $186.
Distance: 349 miles (563 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$60 Average price Cheapest | $177 Average price | $333 Average price |
10h 40m Average total duration 10h 10m Onboard + 30m Additional time* | 6h 29m Average total duration 5h 59m Onboard + 30m Additional time* | 4h 51m Average total duration Fastest 1h 51m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.4kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Frankfurt am Main to Lyon Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:40AM | Arrival Time 12:50PM | Duration 12h10 | Departure days Sat, Sun | Cheapest price $54 |
Operator FlixBus | Departure Time 01:05AM | Arrival Time 04:25PM | Duration 15h20 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $57 |
Operator BlaBlaCar | Departure Time 04:00AM | Arrival Time 11:10AM | Duration 7h10 | Departure days Thu | Cheapest price $81 |
Operator FlixBus | Departure Time 05:55AM | Arrival Time 08:50PM | Duration 14h55 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $58 |
Operator BlaBlaCar | Departure Time 07:00AM | Arrival Time 02:30PM | Duration 7h30 | Departure days Thu | Cheapest price $88 |
Operator BlaBlaCar | Departure Time 07:30AM | Arrival Time 03:10PM | Duration 7h40 | Departure days Wed, Thu, Sun | Cheapest price $41 |
Operator Sindbad | Departure Time 07:35AM | Arrival Time 05:45PM | Duration 10h10 | Departure days Thu | Cheapest price $99 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 03:10PM | Duration 7h10 | Departure days Sat | Cheapest price $82 |
Operator FlixBus | Departure Time 08:15AM | Arrival Time 08:50PM | Duration 12h35 | Departure days Everyday | Cheapest price $74 |
Operator BlaBlaCar Bus | Departure Time 08:55AM | Arrival Time 08:45PM | Duration 11h50 | Departure days Wed, Fri, Sun | Cheapest price $69 |
Operator Alsa | Departure Time 08:55AM | Arrival Time 08:40PM | Duration 11h45 | Departure days Wed, Fri, Sun | Cheapest price $54 |
Operator Alsa | Departure Time 09:30AM | Arrival Time 08:40PM | Duration 11h10 | Departure days Wed, Fri, Sun | Cheapest price $54 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 11:15PM | Duration 12h20 | Departure days Everyday | Cheapest price $65 |
Operator FlixBus | Departure Time 11:20AM | Arrival Time 11:15PM | Duration 11h55 | Departure days Everyday | Cheapest price $54 |
Operator FlixBus | Departure Time 03:30PM | Arrival Time 04:35AM | Duration 13h05 | Departure days Mon, Fri, Sat, Sun | Cheapest price $54 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 04:35AM | Duration 12h35 | Departure days Mon, Fri, Sat, Sun | Cheapest price $55 |
Operator FlixBus | Departure Time 05:50PM | Arrival Time 04:45AM | Duration 10h55 | Departure days Everyday | Cheapest price $55 |
Operator BlaBlaCar Bus | Departure Time 06:30PM | Arrival Time 05:10AM | Duration 10h40 | Departure days Mon, Thu, Fri, Sun | Cheapest price $43 |
Operator FlixBus | Departure Time 06:31PM | Arrival Time 08:15AM | Duration 13h44 | Departure days Fri, Sun | Cheapest price $62 |
Operator FlixBus | Departure Time 06:40PM | Arrival Time 08:15AM | Duration 13h35 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $55 |
Operator FlixBus | Departure Time 07:05PM | Arrival Time 04:45AM | Duration 9h40 | Departure days Everyday | Cheapest price $70 |
Operator FlixBus | Departure Time 07:30PM | Arrival Time 09:45AM | Duration 14h15 | Departure days Everyday | Cheapest price $55 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 10:30AM | Duration 11h45 | Departure days Everyday | Cheapest price $73 |
Operator BlaBlaCar Bus | Departure Time 10:50PM | Arrival Time 01:40PM | Duration 14h50 | Departure days Sat | Cheapest price $64 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 10:30AM | Duration 11h25 | Departure days Everyday | Cheapest price $84 |
Live departures
Frankfurt am Main to Lyon bus times
The table below shows live departures for Frankfurt am Main to Lyon buses for today, Wednesday, April 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 8:55 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 12h20 | 9:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 9:20 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 11h55 | 9:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 3:50 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 10h55 | 2:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 5:05 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 9h40 | 2:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 5:30 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 14h15 | 7:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 8:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 11h45 | 8:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 9:05 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 11h25 | 8:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 11:05 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 15h20 | 2:25 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| Thursday, April 2 | |||||
0 | 5:35 AM Frankfurt am Main, Hauptbahnhof | 10h10 | 3:45 PM Lyon, Gare Perrache | 0 transfersDirect | |
FlixBus | 6:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 12h35 | 6:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Frankfurt am Main to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 01
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Why should you book Frankfurt am Main to Lyon buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus, Infobus or Sindbad to find the best option for your trip from Frankfurt am Main to Lyon.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Frankfurt am Main to Lyon.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus, Infobus or Sindbad to find the best option for your trip from Frankfurt am Main to Lyon.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Frankfurt am Main to Lyon.
Journey information
Overview: Bus from Frankfurt am Main to Lyon
Buses from Frankfurt am Main to Lyon run on average 12 times per day, taking around 10h 10m. Cheap bus tickets for this journey start at $37 (€30) if you book in advance.
There are 5 buses per day. The earliest bus runs at 00:20, the last at 23:55. The fastest bus covers the 349 miles (563 km) distance in 9h 35m.
Distance 349 miles (563 km) |
Average bus duration 10h 10m |
Cheapest ticket price $37 (€30) |
Buses per day 12 |
Direct buses 5 |
Fastest bus 9h 35m |
First bus 12:20 AM |
Last bus 11:55 PM |
Bus providers: FlixBus, BlaBlaCar Bus, Infobus, Sindbad, BlaBlaCar from Frankfurt am Main to LyonYou can travel by bus between Frankfurt am Main to Lyon with FlixBus, BlaBlaCar Bus, Infobus, Sindbad, BlaBlaCar for as low as $37 (€30). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
Sindbad
BlaBlaCar Bus
BlaBlaCar
FAQs: Bus from Frankfurt am Main to Lyon
Find answers to the most common questions about traveling from Frankfurt am Main to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Basilica of Notre-Dame de Fourvière, a stunning 19th-century basilica offering panoramic views of the city
- Vieux Lyon, a UNESCO World Heritage site known for its Renaissance architecture and narrow cobblestone streets
- Parc de la Tête d'Or, a large urban park featuring a zoo, botanical garden, and lake
- Musée des Confluences, a modern science and anthropology museum with innovative exhibits
- Place Bellecour, one of Europe's largest open squares, ideal for shopping and dining.
- Les Halles de Lyon Paul Bocuse, a renowned indoor market offering gourmet food and local specialties
- Take a river cruise on the Rhône and Saône for a unique view of the city
- Explore the traboules, secret passageways in Vieux Lyon
- Attend a performance at the Opéra de Lyon, known for its diverse program
- Visit the Institut Lumière, dedicated to the history of cinema.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Sindbad
- Small pets allowed in carriers
- larger pets may require prior arrangement.
popular bus stations
Popular bus stations from Frankfurt am Main to Lyon
- 00:00-23:59
- Free Wi-Fi
- McDonald's (in the station)
- Hausmann's (in the station).
- Available outside the terminal at designated taxi stands.
- Elevators, ramps, assistance
- Available in the station.
- Bus: 61, 62, 77 Train: S8, S9
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Bistro Lyonnais (0.2 km)
- Fast Food Express (0.3 km).
- Available outside the main entrance.
- Elevators, ramps
- Available on the concourse.
- Bus: C21, C22, S1 Metro: A Train: TER
Most popular bus connections from Frankfurt am Main
More options for your journey from Frankfurt am Main to Lyon
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