Frederick, MD to Buffalo, NY bus with Greyhound

Fri, Apr 03
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Greyhound
BayRunner Shuttle
FlixBus
Alsa
BlaBlaCar Bus
2,000+ travel companies
Greyhound
BayRunner Shuttle
FlixBus
Alsa
BlaBlaCar Bus
2,000+ travel companies
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Travel Information

Compare bus and flight for Frederick, MD to Buffalo, NY

Omio recommends booking the flight as it is the most popular option from Frederick, MD to Buffalo, NY among Omio's users. If you are prioritising price take the bus with prices starting from $75. For those with little time consider booking a flight which can get you there in 4h 25m. The ticket price range depends on the travel mode: a bus costs an average of $75, and a flight costs an average of $113.

Distance: 251 miles (405 km)

Compare bus with

Bus
Most popular
Flight

$83

Average price

Cheapest

$113

Average price

16h 50m

Average total duration

16h 20m

Onboard

+

30m

Additional time*

7h 25m

Average total duration

Fastest

4h 25m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Compare prices and tickets Frederick, MD to Buffalo, NY by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Frederick, MD to Buffalo, NY buses with Omio?

Greyhound as well as BayRunner Shuttle offer buses services from Frederick, MD to Buffalo, NY.
Omio is an official ticket reseller for all your travel options from Frederick, MD to Buffalo, NY.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of BayRunner Shuttle to find the best option for your trip from Frederick, MD to Buffalo, NY.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Frederick, MD to Buffalo, NY.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Frederick, MD to Buffalo, NY.

Journey information

Overview: Bus from Frederick, MD to Buffalo, NY

USAUSA
USAUSA
Icon of bus

Buses from Frederick, MD to Buffalo, NY run on average 5 times per day, taking around 16h 20m. Cheap bus tickets for this journey start at $75 (€61) if you book in advance.

The earliest bus runs at 00:55, the last at 23:55. The fastest bus covers the 251 miles (405 km) distance in 15h 20m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
251 miles (405 km)
Average bus duration
16h 20m
Cheapest ticket price
$75 (€61)
Buses per day
5
Fastest bus
15h 20m
First bus
12:55 AM
Last bus
11:55 PM
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, BayRunner Shuttle from Frederick, MD to Buffalo, NYYou can travel by bus between Frederick, MD to Buffalo, NY with Greyhound, BayRunner Shuttle for as low as $75 (€61). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
14h 40m
Cheapest Price
$213 (€173)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

BayRunner Shuttle

Luggage & cancellation policy
Average Duration
21h 55m
Cheapest Price
$362 (€295)
BayRunner Shuttle frequency
1 a day

FAQs: Bus from Frederick, MD to Buffalo, NY

Find answers to the most common questions about traveling from Frederick, MD to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Frederick, MD to Buffalo, NY can start from as little as $75 (€61) when you book in advance. The average bus ticket price for Frederick, MD to Buffalo, NY is $83 (€67) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Frederick, MD to Buffalo, NY is 15h 20m to travel the 251 miles (405 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Frederick, MD to Buffalo, NY leaves at 12:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Frederick, MD to Buffalo, NY leaves at 11:55 PM.
There are 5 buses a day from Frederick, MD to Buffalo, NY which require at least one change with Greyhound, BayRunner Shuttle. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Frederick, MD to Buffalo, NY, you can count on Greyhound, BayRunner Shuttle for the best way to get you to Buffalo, NY. You can also check all possible bus companies who offer a service between Frederick, MD and Buffalo, NY and compare the amenities they offer before buying a bus ticket.
A trip to Buffalo, NY from Frederick, MD is worth doing but not as a day trip with a journey time of 15h 20m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Frederick, MD to Buffalo, NY is September.
It's helpful to compare your options as there are 2 ways to travel between Frederick, MD and Buffalo, NY including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Frederick, MD to Buffalo, NY:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Frederick, MD to Buffalo, NY for bus company Greyhound.
Whether you can cancel your bus ticket from Frederick, MD to Buffalo, NY depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Frederick, MD to Buffalo, NY.
Yes, the following luggage options are included when booking a bus ticket from Frederick, MD to Buffalo, NY:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Frederick, MD to Buffalo, NY:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Frederick, MD to Buffalo, NY.
You can reserve your seat on the bus from Frederick, MD to Buffalo, NY with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Frederick, MD to Buffalo, NY with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Frederick, MD to Buffalo, NY with the following bus company: Greyhound.
Since neither Frederick, MD nor Buffalo, NY are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Frederick, MD to Buffalo, NY among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Buffalo, NY, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and tourist spots. Scams involving overcharging for taxi or rideshare services have been reported, so it's advised to use licensed transportation and confirm fares beforehand. Additionally, travelers should stay aware of their surroundings at night, particularly in less populated neighborhoods, to avoid potential safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Frederick, MD to Buffalo, NY

Frederick
Buffalo
The major bus station for departures in Frederick is Frederick, East Street (Transit Center). Find all the information you need to know about services, amenities and connections at Frederick, East Street (Transit Center) for your trip from Frederick to Buffalo.
Frederick, East Street (Transit Center)
information

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