Karlovy Vary to Brno bus with FlixBus

Mon, Apr 06
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The cheapest and fastest buses from Karlovy Vary to Brno

Showing times and prices for Apr 06

Cheapest price

$23

Average price

$31

Fastest journey

4 h 50 m

Average duration

5 h 24 m

Buses per day

18

Distance

292 km

Cheap tickets

The best way to find a cheap bus ticket from Karlovy Vary to Brno is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Karlovy Vary to Brno will cost around $31 if you buy it on the day, but the cheapest tickets can be found for only $23.

Fast buses

Of the 18 buses that leave Karlovy Vary for Brno on Mon, Apr 06, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Mon, Apr 06 the direct buses cover the 292 km distance in an average of 5 h 24 m but if you time it right, some buses will get you there in just 4 h 50 m .

On Mon, Apr 06 the slowest buses will take 5 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • RegioJet a.s.(Karlovy Vary -> Prague) · (Prague -> Budapest)
    6:00 AM6h00
    Karlovy Vary, Dolní Nádraží
    12:00 PMBrno, Benešova - Grandhotel (Hlavní nádraží)
    $231One-way
    1 transfer
  • FlixBusFlixBus
    4:10 PM4h50
    Karlovy Vary, Dolní Nádraží
    9:00 PMBrno, Benešova - Grandhotel (Hlavní nádraží)
    $251One-way
    0 transfers
  • FlixBusFlixBus
    5:55 AM6h15
    Karlovy Vary, Dolní Nádraží
    12:10 PMBrno, Benešova - Grandhotel (Hlavní nádraží)
    $251One-way
    0 transfers
  • RegioJet a.s.(Karlovy Vary -> Prague) · (Prague -> Vienna)
    8:00 PM13h30
    Karlovy Vary, Dolní Nádraží
    9:30 AMBrno, Benešova - Grandhotel (Hlavní nádraží)
    $261One-way
    1 transfer
  • RegioJet a.s.(Karlovy Vary -> Prague) · (Prague -> Brno)
    3:00 PM5h30
    Karlovy Vary, Dolní Nádraží
    8:30 PMBrno, Benešova - Grandhotel (Hlavní nádraží)
    $261One-way
    1 transfer

Travel Information

Compare bus and train for Karlovy Vary to Brno

Omio recommends booking the bus as it is the most popular option from Karlovy Vary to Brno among Omio's users. If you are prioritising price take the bus with prices starting from $5. For those with little time consider booking a train which can get you there in 4h 46m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $5, and a train costs an average of $24.

Distance: 181 miles (292 km)

Compare bus with

Most popular
Bus
Train

$11

Average price

Cheapest

$32

Average price

5h 31m

Average total duration

5h 1m

Onboard

+

30m

Additional time*

5h 16m

Average total duration

Fastest

4h 46m

Onboard

+

30m

Additional time*

0.3 - 0.7kg

CO2 emissions

0.1 - 0.3kg

CO2 emissions

Lowest
FlixBus

Most popular bus company

RegioJet a.s.

Most popular train company

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Karlovy Vary to Brno Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
05:55AM
Arrival Time
12:10PM
Duration
6h15
Departure days
Mon
Cheapest price
$25
Operator
RegioJet a.s.
Departure Time
06:00AM
Arrival Time
12:00PM
Duration
6h00
Departure days
Mon
Cheapest price
$23
Operator
FlixBus
Departure Time
06:15AM
Arrival Time
12:10PM
Duration
5h55
Departure days
Mon
Cheapest price
$28
Operator
RegioJet a.s.
Departure Time
07:00AM
Arrival Time
12:55PM
Duration
5h55
Departure days
Mon
Cheapest price
$29
Operator
RegioJet a.s.
Departure Time
08:00AM
Arrival Time
01:30PM
Duration
5h30
Departure days
Mon
Cheapest price
$29
Operator
FlixBus
Departure Time
09:30AM
Arrival Time
04:30PM
Duration
7h00
Departure days
Mon
Cheapest price
$29
Operator
RegioJet a.s.
Departure Time
10:00AM
Arrival Time
03:55PM
Duration
5h55
Departure days
Mon
Cheapest price
$33
Operator
RegioJet a.s.
Departure Time
11:00AM
Arrival Time
04:55PM
Duration
5h55
Departure days
Mon
Cheapest price
$33
Operator
FlixBus
Departure Time
11:30AM
Arrival Time
06:05PM
Duration
6h35
Departure days
Mon
Cheapest price
$37
Operator
FlixBus
Departure Time
12:30PM
Arrival Time
07:25PM
Duration
6h55
Departure days
Mon
Cheapest price
$45
Operator
RegioJet a.s.
Departure Time
01:00PM
Arrival Time
06:35PM
Duration
5h35
Departure days
Mon
Cheapest price
$33
Operator
RegioJet a.s.
Departure Time
02:00PM
Arrival Time
07:35PM
Duration
5h35
Departure days
Mon
Cheapest price
$33
Operator
RegioJet a.s.
Departure Time
03:00PM
Arrival Time
08:30PM
Duration
5h30
Departure days
Mon
Cheapest price
$26
Operator
RegioJet a.s.
Departure Time
04:00PM
Arrival Time
09:55PM
Duration
5h55
Departure days
Mon
Cheapest price
$33
Operator
FlixBus
Departure Time
04:10PM
Arrival Time
09:00PM
Duration
4h50
Departure days
Mon
Cheapest price
$25
Operator
RegioJet a.s.
Departure Time
05:00PM
Arrival Time
10:55PM
Duration
5h55
Departure days
Mon
Cheapest price
$28
Operator
RegioJet a.s.
Departure Time
06:00PM
Arrival Time
04:00AM
Duration
10h00
Departure days
Mon
Cheapest price
$39
Operator
RegioJet a.s.
Departure Time
08:00PM
Arrival Time
09:30AM
Duration
13h30
Departure days
Mon
Cheapest price
$26

Live departures

Karlovy Vary to Brno bus times

The table below shows live departures for Karlovy Vary to Brno buses for tomorrow, Sunday, April 5. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus3:55 AM Karlovy Vary, Dolní Nádraží
6h15
10:10 AM Brno, Benešova - Grandhotel (Hlavní nádraží)0 transfersDirect
studentagencyconnect_regio_jet(Karlovy Vary -> Prague) · (Prague -> Budapest)4:00 AM Karlovy Vary, Dolní Nádraží
6h00
10:00 AM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
meinfernbus_flixbusFlixBus · FlixBus4:15 AM Karlovy Vary, Dolní Nádraží
5h55
10:10 AM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
studentagencyconnect_regio_jet(Karlovy Vary -> Prague) · (Prague -> Brno)5:00 AM Karlovy Vary, Dolní Nádraží
5h55
10:55 AM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
studentagencyconnect_regio_jet(Cheb -> Prague) · (Prague -> Brno)6:00 AM Karlovy Vary, Dolní Nádraží
5h30
11:30 AM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
meinfernbus_flixbusFlixBus · FlixBus7:30 AM Karlovy Vary, Dolní Nádraží
7h00
2:30 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
studentagencyconnect_regio_jet(Karlovy Vary -> Prague) · (Prague -> Brno)8:00 AM Karlovy Vary, Dolní Nádraží
5h55
1:55 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
studentagencyconnect_regio_jet(Karlovy Vary -> Prague) · (Prague -> Brno)9:00 AM Karlovy Vary, Dolní Nádraží
5h55
2:55 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
meinfernbus_flixbusFlixBus · FlixBus9:30 AM Karlovy Vary, Dolní Nádraží
6h35
4:05 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
meinfernbus_flixbusFlixBus · FlixBus10:30 AM Karlovy Vary, Dolní Nádraží
6h55
5:25 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
studentagencyconnect_regio_jet(Karlovy Vary -> Prague) · (Prague -> Brno)11:00 AM Karlovy Vary, Dolní Nádraží
5h35
4:35 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
studentagencyconnect_regio_jet(Karlovy Vary -> Prague) · (Prague -> Brno)12:00 PM Karlovy Vary, Dolní Nádraží
5h35
5:35 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
studentagencyconnect_regio_jet(Karlovy Vary -> Prague) · (Prague -> Brno)1:00 PM Karlovy Vary, Dolní Nádraží
5h30
6:30 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
studentagencyconnect_regio_jet(Karlovy Vary -> Prague) · (Prague -> Brno)2:00 PM Karlovy Vary, Dolní Nádraží
5h55
7:55 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
meinfernbus_flixbusFlixBus2:10 PM Karlovy Vary, Dolní Nádraží
4h50
7:00 PM Brno, Benešova - Grandhotel (Hlavní nádraží)0 transfersDirect
studentagencyconnect_regio_jet(Karlovy Vary -> Prague) · (Prague -> Brno)3:00 PM Karlovy Vary, Dolní Nádraží
5h55
8:55 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Karlovy Vary to Brno by bus or train

Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Apr 06
Tue
Apr 07
Wed
Apr 08
Thu
Apr 09
Fri
Apr 10
Sat
Apr 11
Sun
Apr 12

Why should you book Karlovy Vary to Brno buses with Omio?

FlixBus operates all buses services from Karlovy Vary to Brno.
Omio is an official ticket reseller for all your travel options from Karlovy Vary to Brno.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and train to ensure you get the best deal for traveling from Karlovy Vary to Brno.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Karlovy Vary to Brno.

Journey information

Overview: Bus from Karlovy Vary to Brno

CzechiaCzechia
CzechiaCzechia
Icon of bus

Buses from Karlovy Vary to Brno run on average 17 times per day, taking around 5h 1m. Cheap bus tickets for this journey start at $5 (€4) if you book in advance.

There are 1 buses per day. The earliest bus runs at 03:15, the last at 21:20. The fastest bus covers the 181 miles (292 km) distance in 5h 10m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
181 miles (292 km)
Average bus duration
5h 1m
Cheapest ticket price
$5 (€4)
Buses per day
17
Direct buses
1
Fastest bus
5h 10m
First bus
3:15 AM
Last bus
9:20 PM
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus from Karlovy Vary to BrnoYou can travel by bus between Karlovy Vary to Brno with FlixBus for as low as $5 (€4). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
5h 10m
Cheapest Price
$5 (€4)
FlixBus frequency
7 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

FAQs: Bus from Karlovy Vary to Brno

Find answers to the most common questions about traveling from Karlovy Vary to Brno by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brno, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Karlovy Vary to Brno can start from as little as $5 (€4) when you book in advance. The average bus ticket price for Karlovy Vary to Brno is $11 (€9) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Karlovy Vary to Brno is 5h 10m to travel the 181 miles (292 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Karlovy Vary to Brno leaves at 3:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Karlovy Vary to Brno leaves at 9:20 PM.
Yes, there are 1 direct buses a day from Karlovy Vary to Brno with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Karlovy Vary to Brno, you can count on FlixBus for the best way to get you to Brno. You can also check all possible bus companies who offer a service between Karlovy Vary and Brno and compare the amenities they offer before buying a bus ticket.
When departing from Karlovy Vary , you have various bus station options to start your journey from including Karlovy Vary, Dolní Nádraží, Sokolov, Těšovice . When arriving in Brno , you can end your journey in bus stations like Brno, Benešova - Grandhotel (Hlavní nádraží) .Passengers board the bus most frequently from Karlovy Vary, Dolní Nádraží, which is located around 0 away from the city centre, and they get off the bus at Brno, Benešova - Grandhotel (Hlavní nádraží), located 0 away from the city centre.
A trip to Brno from Karlovy Vary is worth doing but not as a day trip with a journey time of 5h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Karlovy Vary to Brno is January.
It's helpful to compare your options as there are 2 ways to travel between Karlovy Vary and Brno including taking a bus and train.
Yes, the following accessibility options are available when taking the bus from Karlovy Vary to Brno:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Karlovy Vary to Brno for bus company FlixBus.
Some of the most interesting sights to explore in Brno are:
  • Špilberk Castle, a historic fortress offering panoramic views of the city and housing a museum
  • Cathedral of St. Peter and Paul, a striking Gothic cathedral known for its twin spires and rich history
  • Villa Tugendhat, a UNESCO World Heritage site showcasing modernist architecture by Mies van der Rohe
  • Brno Underground, a network of historical tunnels and cellars beneath the city center
  • Moravian Museum, the second-largest museum in the Czech Republic, featuring diverse exhibits on natural history and culture.
The best things to do in Brno include:
  • Moravian Karst, a natural reserve with stunning caves and hiking trails located just outside the city
  • Brno Technical Museum, an interactive museum featuring exhibits on the history of technology and industry in the region
  • Mendel Museum, dedicated to the life and work of Gregor Mendel, the father of genetics
  • Lužánky Park, the oldest public park in Brno, perfect for a leisurely stroll or a picnic
  • Brno Zoo, offering a fun and educational experience with a variety of animal species.
Whether you can cancel your bus ticket from Karlovy Vary to Brno depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Karlovy Vary to Brno.
Yes, the following luggage options are included when booking a bus ticket from Karlovy Vary to Brno:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Karlovy Vary to Brno:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Karlovy Vary to Brno. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Karlovy Vary to Brno with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Karlovy Vary to Brno with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Karlovy Vary to Brno with the following bus company: FlixBus.

popular bus stations

Popular bus stations from Karlovy Vary to Brno

Karlovy Vary
Brno
The major bus station for departures in Karlovy Vary is Karlovy Vary, Dolní Nádraží. Find all the information you need to know about services, amenities and connections at Karlovy Vary, Dolní Nádraží for your trip from Karlovy Vary to Brno.
Amenities at bus station
WifiWifi
ParkingParking
DiningDining
ATMATM
AccessibilityAccessibility
WCWC
Ticket OfficeTicket Office
information
ticketOfficeHours
Ticket Office Hours
  • 05:00-23:00
carConnection
Car connection
Západní
Wifi
Wifi
  • Free Wi-Fi
Dining
Dining
  • Cafeteria Dolní (in the station)
  • Fast Food Express (in the station)
  • Coffee Corner (in the station).
Accessibility
Accessibility
  • Elevators, ramps
WC
WC
  • Available near the waiting area.
Public transit options for Karlovy Vary, Dolní Nádraží
  • Bus: 1, 2, 3, 4, 6, 10 Train: Regional

More options for your journey from Karlovy Vary to Brno

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