The cheapest and fastest buses from Karlovy Vary to Frankfurt am Main
Cheapest price
$74
Average price
$135
Fastest journey
6 h 55 m
Average duration
10 h 14 m
Buses per day
7
Distance
298 km
The best way to find a cheap bus ticket from Karlovy Vary to Frankfurt am Main is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlovy Vary to Frankfurt am Main will cost around $135 if you buy it on the day, but the cheapest tickets can be found for only $74.
Of the 7 buses that leave Karlovy Vary for Frankfurt am Main on Mon, Apr 06, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Apr 06 the direct buses cover the 298 km distance in an average of 10 h 14 m but if you time it right, some buses will get you there in just 6 h 55 m .
On Mon, Apr 06 the slowest buses will take 12 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
(Karlovy Vary -> Prague) · (Prague -> Amsterdam)8:00 PM9h25Karlovy Vary, Dolní Nádraží5:25 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$741One-way1 transfer
FlixBus2:35 PM6h55Karlovy Vary, Dolní Nádraží9:30 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$1151One-way0 transfers
FlixBus · FlixBus6:30 PM12h00Karlovy Vary, Dolní Nádraží6:30 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$1281One-way1 transfer
FlixBus · FlixBus2:35 PM11h00Karlovy Vary, Dolní Nádraží1:35 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$1301One-way1 transfer
FlixBus · FlixBus6:15 AM13h10Karlovy Vary, Dolní Nádraží7:25 PMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$1621One-way1 transfer
FlixBus2:35 PM6h55Karlovy Vary, Dolní Nádraží9:30 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$1151One-way0 transfers
(Karlovy Vary -> Prague) · (Prague -> Amsterdam)8:00 PM9h25Karlovy Vary, Dolní Nádraží5:25 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$741One-way1 transfer
FlixBus · FlixBus2:35 PM11h00Karlovy Vary, Dolní Nádraží1:35 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$1301One-way1 transfer
FlixBus · FlixBus12:30 PM11h50Karlovy Vary, Dolní Nádraží12:20 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$1661One-way1 transfer
FlixBus · FlixBus6:30 PM12h00Karlovy Vary, Dolní Nádraží6:30 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$1281One-way1 transfer
Travel Information
Compare bus, train, and flight for Karlovy Vary to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Karlovy Vary to Frankfurt am Main among Omio's users. If you are prioritising price take the train with prices starting from $28. For those with little time consider booking a train which can get you there in 5h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a train costs an average of $28, and a flight costs an average of $104.
Distance: 185 miles (298 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$47 Average price | $40 Average price Cheapest | $155 Average price |
8h 34m Average total duration 8h 4m Onboard + 30m Additional time* | 5h 49m Average total duration Fastest 5h 19m Onboard + 30m Additional time* | 12h 18m Average total duration 9h 18m Onboard + 3h 0m Additional time* |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Karlovy Vary to Frankfurt am Main Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:15AM | Arrival Time 07:25PM | Duration 13h10 | Departure days Mon | Cheapest price $162 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 12:20AM | Duration 11h50 | Departure days Mon | Cheapest price $166 |
Operator FlixBus | Departure Time 02:35PM | Arrival Time 09:30PM | Duration 6h55 | Departure days Mon | Cheapest price $115 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 05:35AM | Duration 12h30 | Departure days Mon | Cheapest price $168 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 06:30AM | Duration 12h00 | Departure days Mon | Cheapest price $128 |
Operator RegioJet a.s. | Departure Time 08:00PM | Arrival Time 05:25AM | Duration 9h25 | Departure days Mon | Cheapest price $74 |
Live departures
Karlovy Vary to Frankfurt am Main bus times
The table below shows live departures for Karlovy Vary to Frankfurt am Main buses for today, Sunday, April 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:35 PM Karlovy Vary | 6h55 | 8:30 PM Frankfurt am Main | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Karlovy Vary to Frankfurt am Main by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 06
Apr 07
Apr 08
Apr 09
Apr 10
Apr 11
Apr 12
Why should you book Karlovy Vary to Frankfurt am Main buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Karlovy Vary to Frankfurt am Main.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Karlovy Vary to Frankfurt am Main.
Journey information
Overview: Bus from Karlovy Vary to Frankfurt am Main
Buses from Karlovy Vary to Frankfurt am Main run on average 6 times per day, taking around 8h 4m. Cheap bus tickets for this journey start at $26 (€22) if you book in advance.
There are 1 buses per day. The earliest bus runs at 03:15, the last at 23:30. The fastest bus covers the 185 miles (298 km) distance in 6h 55m.
Distance 185 miles (298 km) |
Average bus duration 8h 4m |
Cheapest ticket price $26 (€22) |
Buses per day 6 |
Direct buses 1 |
Fastest bus 6h 55m |
First bus 3:15 AM |
Last bus 11:30 PM |
Bus providers: FlixBus from Karlovy Vary to Frankfurt am MainYou can travel by bus between Karlovy Vary to Frankfurt am Main with FlixBus for as low as $26 (€22). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Karlovy Vary to Frankfurt am Main
Find answers to the most common questions about traveling from Karlovy Vary to Frankfurt am Main by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Römer, a historic city hall with medieval architecture located in the heart of Frankfurt's old town
- Städel Museum, an art museum featuring a vast collection of European artworks from the Middle Ages to the present
- Palmengarten, a large botanical garden showcasing diverse plant species in themed greenhouses and outdoor areas
- Goethe House, the birthplace of the famous writer Johann Wolfgang von Goethe, now a museum dedicated to his life and works
- Frankfurt Cathedral, a Gothic-style church with a rich history and stunning architecture.
- Main Tower, a skyscraper with an observation deck providing panoramic views of the city
- Explore the vibrant Kleinmarkthalle, an indoor market offering a variety of local and international foods
- Visit the Senckenberg Natural History Museum, home to an extensive collection of dinosaur fossils and natural exhibits
- Take a leisurely walk along the River Main and enjoy the scenic views
- Experience the lively atmosphere of the Zeil, Frankfurt's premier shopping street.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Karlovy Vary to Frankfurt am Main
- 05:00-23:00
- Free Wi-Fi
- Cafeteria Dolní (in the station)
- Fast Food Express (in the station)
- Coffee Corner (in the station).
- Elevators, ramps
- Available near the waiting area.
- Bus: 1, 2, 3, 4, 6, 10 Train: Regional
- 00:00-23:59
- Free Wi-Fi
- McDonald's (in the station)
- Hausmann's (in the station).
- Available outside the terminal at designated taxi stands.
- Elevators, ramps, assistance
- Available in the station.
- Bus: 61, 62, 77 Train: S8, S9
Most popular bus connections from Karlovy Vary
More options for your journey from Karlovy Vary to Frankfurt am Main
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