The cheapest and fastest buses from Orlando, FL to Des Moines, IA
Cheapest price
$256
Average price
$256
Fastest journey
1 d 16 h 40 m
Average duration
1 d 16 h 40 m
Buses per day
1
Distance
1826 km
The best way to find a cheap bus ticket from Orlando, FL to Des Moines, IA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Des Moines, IA will cost around $256 if you buy it on the day, but the cheapest tickets can be found for only $256.
Of the 1 buses that leave Orlando, FL for Des Moines, IA on Tue, Apr 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Apr 07 the direct buses cover the 1826 km distance in an average of 1 d 16 h 40 m but if you time it right, some buses will get you there in just 1 d 16 h 40 m .
On Tue, Apr 07 the slowest buses will take 1 d 16 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
3:55 AM40h40Orlando, FL8:35 PMDes Moines, IA$2561One-way0 transfers
3:55 AM40h40Orlando, FL8:35 PMDes Moines, IA$2561One-way0 transfers
Travel Information
Compare bus and flight for Orlando, FL to Des Moines, IA
Omio recommends booking the flight as it is the most popular option from Orlando, FL to Des Moines, IA among Omio's users. If you are prioritising price take the flight with prices starting from $186. For those with little time consider booking a flight which can get you there in 3h 58m. The ticket price range depends on the travel mode: a flight costs an average of $186, and a bus costs an average of $256.
Distance: 1134 miles (1826 km)
Compare bus with
| Bus | Most popular Flight |
|---|---|
$366 Average price | $308 Average price Cheapest |
33h 40m Average total duration 33h 10m Onboard + 30m Additional time* | 6h 58m Average total duration Fastest 3h 58m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Orlando, FL to Des Moines, IA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 09:00AM | Arrival Time 06:55PM | Duration 34h55 | Departure days Sun | Cheapest price $489 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 11:45PM | Duration 34h45 | Departure days Sun | Cheapest price $382 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 11:45PM | Duration 34h00 | Departure days Sun | Cheapest price $382 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 02:35PM | Duration 40h40 | Departure days Sun | Cheapest price $431 |
Live departures
Orlando, FL to Des Moines, IA bus times
The table below shows live departures for Orlando, FL to Des Moines, IA buses for today, Sunday, April 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus+![]() | 1:00 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 34h55 | 11:55 PM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 2 transfers | |
FlixBus · FlixBus+![]() | 6:00 PM Orlando, The Florida Mall, FL | 34h45 | 4:45 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 2 transfers | |
FlixBus · FlixBus+![]() | 6:45 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 34h00 | 4:45 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 2 transfers | |
| Monday, April 6 | |||||
FlixBus · FlixBus+![]() | 2:55 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 40h40 | 7:35 PM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 2 transfers | |
![]() | 3:55 AM Orlando, FL | 40h40 | 8:35 PM Des Moines, IA | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Orlando, FL to Des Moines, IA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 06
Apr 07
Apr 08
Apr 09
Apr 10
Apr 11
Apr 12
Why should you book Orlando, FL to Des Moines, IA buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Orlando, FL to Des Moines, IA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Orlando, FL to Des Moines, IA.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Orlando, FL to Des Moines, IA.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Orlando, FL to Des Moines, IA.
Journey information
Overview: Bus from Orlando, FL to Des Moines, IA
Buses from Orlando, FL to Des Moines, IA run on average 2 times per day, taking around 33h 10m. Cheap bus tickets for this journey start at $256 (€209) but you can travel from only $186 (€152) by flight.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 1134 miles (1826 km) distance in 34h 35m.
Distance 1134 miles (1826 km) |
Average bus duration 33h 10m |
Cheapest ticket price $256 (€209) |
Buses per day 2 |
Fastest bus 34h 35m |
First bus 4:00 AM |
Last bus 11:40 PM |
Bus providers: FlixBus, Greyhound from Orlando, FL to Des Moines, IAYou can travel by bus between Orlando, FL to Des Moines, IA with FlixBus, Greyhound for as low as $186 (€152). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Orlando, FL to Des Moines, IA
Find answers to the most common questions about traveling from Orlando, FL to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Orlando, FL to Des Moines, IA
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Des Moines, IA
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