4.9
4.6The cheapest and fastest buses from St. Louis, MO to Des Moines, IA
Cheapest price
$142
Average price
$142
Fastest journey
15 h 5 m
Average duration
15 h 5 m
Buses per day
1
Distance
440 km
The best way to find a cheap bus ticket from St. Louis, MO to Des Moines, IA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Des Moines, IA will cost around $142 if you buy it on the day, but the cheapest tickets can be found for only $142.
Of the 1 buses that leave St. Louis, MO for Des Moines, IA on Tue, Apr 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Apr 07 the direct buses cover the 440 km distance in an average of 15 h 5 m but if you time it right, some buses will get you there in just 15 h 5 m .
On Tue, Apr 07 the slowest buses will take 15 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
5:30 AM15h05St. Louis, MO8:35 PMDes Moines, IA$1421One-way0 transfers
- 5:30 AM15h05St. Louis, MO8:35 PMDes Moines, IA$1421One-way0 transfers
Travel Information
Compare bus and flight for St. Louis, MO to Des Moines, IA
Omio recommends booking the flight as it is the most popular option from St. Louis, MO to Des Moines, IA among Omio's users. If you are prioritising price take the bus with prices starting from $92. For those with little time consider booking a flight which can get you there in 3h 22m. The ticket price range depends on the travel mode: a bus costs an average of $92, and a flight costs an average of $85.
Distance: 273 miles (440 km)
Compare bus with
| Bus | Most popular Flight |
|---|---|
$149 Average price Cheapest | $265 Average price |
15h 30m Average total duration 15h 0m Onboard + 30m Additional time* | 6h 22m Average total duration Fastest 3h 22m Onboard + 3h 0m Additional time* |
Most popular bus company |  Most popular airline |
Direct Options | Direct Options |
St. Louis, MO to Des Moines, IA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:20PM | Arrival Time 11:45PM | Duration 8h25 | Departure days Sun | Cheapest price $71 |
Operator Greyhound | Departure Time 11:30PM | Arrival Time 02:35PM | Duration 15h05 | Departure days Sun | Cheapest price $93 |
Live departures
St. Louis, MO to Des Moines, IA bus times
The table below shows live departures for St. Louis, MO to Des Moines, IA buses for today, Sunday, April 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 8:20 PM St. Louis, S 15th St (Civic center) | 8h25 | 4:45 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 0 transfersDirect | |
| Monday, April 6 | |||||
 FlixBus+ | 4:30 AM St. Louis, S 15th St (Civic center) | 15h05 | 7:35 PM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 1 transfer | |
| 5:30 AM St. Louis, MO | 15h05 | 8:35 PM Des Moines, IA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Des Moines, IA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 06
Apr 07
Apr 08
Apr 09
Apr 10
Apr 11
Apr 12
Why should you book St. Louis, MO to Des Moines, IA buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of Metro St. Louis to find the best option for your trip from St. Louis, MO to Des Moines, IA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Des Moines, IA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from St. Louis, MO to Des Moines, IA.
Journey information
Overview: Bus from St. Louis, MO to Des Moines, IA
USAUSA
Buses from St. Louis, MO to Des Moines, IA run on average 1 times per day, taking around 15h 0m. Cheap bus tickets for this journey start at $92 (€75) but you can travel from only $85 (€70) by flight.
The earliest bus runs at 05:30, the last at 23:30. The fastest bus covers the 273 miles (440 km) distance in 15h 5m.
Distance 273 miles (440 km) |
Average bus duration 15h 0m |
Cheapest ticket price $92 (€75) |
Buses per day 1 |
Fastest bus 15h 5m |
First bus 5:30 AM |
Last bus 11:30 PM |
Bus providers: Greyhound, Metro St. Louis from St. Louis, MO to Des Moines, IAYou can travel by bus between St. Louis, MO to Des Moines, IA with Greyhound, Metro St. Louis for as low as $85 (€70). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
Metro St. Louis
FAQs: Bus from St. Louis, MO to Des Moines, IA
Find answers to the most common questions about traveling from St. Louis, MO to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from St. Louis, MO to Des Moines, IA
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Des Moines, IA
Here are some other resources that might have the information you need
Most popular buses to and from Des Moines, IA and St. Louis, MO
Most popular bus connections to Des Moines, IA
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