The cheapest and fastest buses from St. Louis, MO to Houston, TX
Cheapest price
$254
Average price
$278
Fastest journey
20 h 5 m
Average duration
21 h 12 m
Buses per day
9
Distance
1094 km
The best way to find a cheap bus ticket from St. Louis, MO to Houston, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Houston, TX will cost around $278 if you buy it on the day, but the cheapest tickets can be found for only $254.
It's difficult to get from St. Louis, MO to Houston, TX without transferring at least once.
undefined · undefined1:30 AM22h00St. Louis, S 15th St (Civic center)11:30 PMHouston, Harrisburg Blvd (Greyhound Bus Station), TX$2541One-way1 transfer
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FlixBus1:00 AM28h15St. Louis, S 15th St (Civic center)5:15 AMHouston, Gray St Parking (Bus Station), TX$2551One-way1 transfer
undefined · undefined · undefined1:20 AM21h30St. Louis, S 15th St (Civic center)10:50 PMHouston, Harrisburg Blvd (Greyhound Bus Station), TX$2571One-way2 transfers
undefined · undefined · undefined4:30 PM25h25St. Louis, S 15th St (Civic center)5:55 PMHouston, Harrisburg Blvd (Greyhound Bus Station), TX$2641One-way2 transfers
undefined · undefined+
FlixBus4:30 PM23h50St. Louis, S 15th St (Civic center)4:20 PMHouston, Gray St Parking (Bus Station), TX$2641One-way2 transfers
FlixBus+
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FlixBus4:00 PM20h05St. Louis, S 15th St (Civic center)12:05 PMHouston, Gray St Parking (Bus Station), TX$3201One-way2 transfers
FlixBus+
undefined · undefined4:00 PM20h40St. Louis, S 15th St (Civic center)12:40 PMHouston, Harrisburg Blvd (Greyhound Bus Station), TX$3001One-way2 transfers
undefined · undefined · undefined1:20 AM21h30St. Louis, S 15th St (Civic center)10:50 PMHouston, Harrisburg Blvd (Greyhound Bus Station), TX$2571One-way2 transfers
FlixBus+
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FlixBus4:00 PM21h45St. Louis, S 15th St (Civic center)1:45 PMHouston, Southwest Fwy (Shell), TX$3231One-way3 transfers
undefined · undefined1:30 AM22h00St. Louis, S 15th St (Civic center)11:30 PMHouston, Harrisburg Blvd (Greyhound Bus Station), TX$2541One-way1 transfer
Travel Information
Compare bus, train, and flight for St. Louis, MO to Houston, TX
Omio recommends booking the train as it is the most popular option from St. Louis, MO to Houston, TX among Omio's users. If you are prioritising price take the train with prices starting from $157. For those with little time consider booking a flight which can get you there in 2h 28m. The ticket price range depends on the travel mode: a train costs an average of $157, and a flight costs an average of $195.
Distance: 679 miles (1094 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$210 Average price | $182 Average price Cheapest | $427 Average price |
24h 58m Average total duration 24h 28m Onboard + 30m Additional time* | 18h 2m Average total duration 17h 32m Onboard + 30m Additional time* | 5h 28m Average total duration Fastest 2h 28m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
St. Louis, MO to Houston, TX Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:00AM | Arrival Time 05:15AM | Duration 28h15 | Departure days Thu, Fri, Sat | Cheapest price $144 |
Operator Greyhound | Departure Time 01:20AM | Arrival Time 10:50PM | Duration 21h30 | Departure days Wed, Thu, Fri, Sat | Cheapest price $142 |
Operator Greyhound | Departure Time 01:30AM | Arrival Time 11:30PM | Duration 22h00 | Departure days Wed, Thu, Fri, Sat | Cheapest price $142 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 12:40PM | Duration 20h40 | Departure days Thu, Fri, Sat | Cheapest price $143 |
Operator Greyhound | Departure Time 04:30PM | Arrival Time 05:55PM | Duration 25h25 | Departure days Wed, Thu, Fri, Sat | Cheapest price $144 |
Live departures
St. Louis, MO to Houston, TX bus times
The table below shows live departures for St. Louis, MO to Houston, TX buses for today, Wednesday, April 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
undefined · undefined+ + FlixBus | 9:30 PM St. Louis, S 15th St (Civic center) | 26h30 | 12:00 AM Houston, Southwest Fwy (Shell), TX | 3 transfers | |
undefined · undefined · undefined | 9:30 PM St. Louis, S 15th St (Civic center) | 25h25 | 10:55 PM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 2 transfers | |
| Thursday, April 2 | |||||
+ FlixBus | 6:00 AM St. Louis, S 15th St (Civic center) | 28h15 | 10:15 AM Houston, Gray St Parking (Bus Station), TX | 1 transfer | |
undefined · undefined · undefined | 6:20 AM St. Louis, S 15th St (Civic center) | 21h30 | 3:50 AM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 2 transfers | |
undefined · undefined | 6:30 AM St. Louis, S 15th St (Civic center) | 22h00 | 4:30 AM Houston, Harrisburg Blvd (Greyhound Bus Station), TX | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Houston, TX by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Apr 08
Why should you book St. Louis, MO to Houston, TX buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from St. Louis, MO to Houston, TX.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from St. Louis, MO to Houston, TX.
Journey information
Overview: Bus from St. Louis, MO to Houston, TX
Buses from St. Louis, MO to Houston, TX run on average 9 times per day, taking around 24h 28m. Cheap bus tickets for this journey start at $133 (€108) if you book in advance.
The earliest bus runs at 00:05, the last at 23:45. The fastest bus covers the 679 miles (1094 km) distance in 20h 0m.
Distance 679 miles (1094 km) |
Average bus duration 24h 28m |
Cheapest ticket price $133 (€108) |
Buses per day 9 |
Fastest bus 20h 0m |
First bus 12:05 AM |
Last bus 11:45 PM |
Bus providers: Greyhound from St. Louis, MO to Houston, TXYou can travel by bus between St. Louis, MO to Houston, TX with Greyhound for as low as $133 (€108). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from St. Louis, MO to Houston, TX
Find answers to the most common questions about traveling from St. Louis, MO to Houston, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Houston, TX, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Space Center Houston, an educational complex offering exhibits and tours related to NASA's space exploration
- Houston Museum of Natural Science, featuring extensive collections of fossils, gems, and ancient artifacts
- Houston Zoo, home to over 6,000 animals from around the world in a lush, 55-acre park
- Museum of Fine Arts, Houston, showcasing a diverse collection of art from antiquity to the present
- Buffalo Bayou Park, a 160-acre green space with trails, gardens, and views of the downtown skyline.
- Visit the Houston Livestock Show and Rodeo, the largest livestock exhibition and rodeo in the world, featuring concerts and carnival attractions
- Explore the vibrant street art and murals in the Houston Heights neighborhood
- Enjoy a performance at the Houston Symphony, offering a range of classical and contemporary music
- Discover the culinary scene with a food tour in the diverse neighborhoods of Houston
- Attend a game at Minute Maid Park, home of the Houston Astros, for an exciting baseball experience.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from St. Louis, MO to Houston, TX
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Houston, TX
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