The cheapest and fastest buses from St. Louis, MO to Los Angeles, CA
Cheapest price
$473
Average price
$490
Fastest journey
1 d 16 h 30 m
Average duration
1 d 17 h 8 m
Buses per day
2
Distance
2553 km
The best way to find a cheap bus ticket from St. Louis, MO to Los Angeles, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Los Angeles, CA will cost around $490 if you buy it on the day, but the cheapest tickets can be found for only $473.
Of the 2 buses that leave St. Louis, MO for Los Angeles, CA on Thu, Apr 02, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Apr 02 the direct buses cover the 2553 km distance in an average of 1 d 17 h 8 m but if you time it right, some buses will get you there in just 1 d 16 h 30 m .
On Thu, Apr 02 the slowest buses will take 1 d 17 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
07:20AM40h30St. Louis, MO11:50PMLos Angeles, CA$4731One-way0 transfers
10:30PM41h45St. Louis, MO04:15PMLos Angeles, CA$5081One-way0 transfers
07:20AM40h30St. Louis, MO11:50PMLos Angeles, CA$4731One-way0 transfers
10:30PM41h45St. Louis, MO04:15PMLos Angeles, CA$5081One-way0 transfers
Travel Information
Compare bus, train, and flight for St. Louis, MO to Los Angeles, CA
Omio recommends booking the train as it is the most popular option from St. Louis, MO to Los Angeles, CA among Omio's users. If you are prioritising price take the bus with prices starting from $130. For those with little time consider booking a flight which can get you there in 4h 33m. The ticket price range depends on the travel mode: a bus costs an average of $130, and a train costs an average of $175.
Distance: 1586 miles (2553 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$279 Average price Cheapest | $336 Average price | $336 Average price |
39h 26m Average total duration 38h 56m Onboard + 30m Additional time* | 50h 41m Average total duration 50h 11m Onboard + 30m Additional time* | 7h 33m Average total duration Fastest 4h 33m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
St. Louis, MO to Los Angeles, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:20AM | Arrival Time 03:50PM | Duration 40h30 | Departure days Wed, Fri, Sat | Cheapest price $180 |
Operator Greyhound | Departure Time 08:40AM | Arrival Time 10:30PM | Duration 39h50 | Departure days Wed, Fri, Sat | Cheapest price $230 |
Operator Greyhound | Departure Time 09:10AM | Arrival Time 10:30PM | Duration 39h20 | Departure days Wed, Fri, Sat | Cheapest price $230 |
Operator Greyhound | Departure Time 04:30PM | Arrival Time 08:15AM | Duration 41h45 | Departure days Wed, Fri, Sat | Cheapest price $239 |
Live departures
St. Louis, MO to Los Angeles, CA bus times
The table below shows live departures for St. Louis, MO to Los Angeles, CA buses for today, Wednesday, April 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
undefined · undefined | 1:40 PM St. Louis, S 15th St (Civic center) | 39h50 | 5:30 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 1 transfer | |
undefined · undefined | 2:10 PM St. Louis, Lambert International Airport | 39h20 | 5:30 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 1 transfer | |
undefined · undefined · undefined+ FlixBus | 9:30 PM St. Louis, S 15th St (Civic center) | 49h00 | 10:30 PM Los Angeles, Cesar E Chavez / Vignes, CA | 3 transfers | |
undefined · undefined · undefined | 9:30 PM St. Louis, S 15th St (Civic center) | 41h45 | 3:15 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 2 transfers | |
| Thursday, April 2 | |||||
![]() | 7:20 AM St. Louis, MO | 40h30 | 11:50 PM Los Angeles, CA | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Los Angeles, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 02
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Apr 08
Why should you book St. Louis, MO to Los Angeles, CA buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from St. Louis, MO to Los Angeles, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from St. Louis, MO to Los Angeles, CA.
Journey information
Overview: Bus from St. Louis, MO to Los Angeles, CA
Buses from St. Louis, MO to Los Angeles, CA run on average 6 times per day, taking around 38h 56m. Cheap bus tickets for this journey start at $130 (€105) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:25, the last at 23:55. The fastest bus covers the 1586 miles (2553 km) distance in 39h 40m.
Distance 1586 miles (2553 km) |
Average bus duration 38h 56m |
Cheapest ticket price $130 (€105) |
Buses per day 6 |
Direct buses 2 |
Fastest bus 39h 40m |
First bus 00:25 |
Last bus 23:55 |
Bus providers: Greyhound from St. Louis, MO to Los Angeles, CAYou can travel by bus between St. Louis, MO to Los Angeles, CA with Greyhound for as low as $130 (€105). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from St. Louis, MO to Los Angeles, CA
Find answers to the most common questions about traveling from St. Louis, MO to Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Los Angeles, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Griffith Observatory, an iconic facility offering stunning views of Los Angeles and exhibits on astronomy
- The Getty Center, a renowned art museum with impressive architecture and beautiful gardens
- Santa Monica Pier, a historic landmark featuring an amusement park, aquarium, and scenic ocean views
- Hollywood Walk of Fame, a famous sidewalk celebrating entertainment industry icons with star plaques
- Los Angeles County Museum of Art (LACMA), the largest art museum in the western United States with diverse collections.
- Explore the vibrant Venice Beach Boardwalk, known for its eclectic shops, street performers, and skate park
- Visit the historic El Capitan Theatre for a classic movie experience
- Take a scenic hike in Runyon Canyon Park, offering panoramic views of the city
- Enjoy a live performance at the Walt Disney Concert Hall, known for its stunning architecture and acoustics
- Discover the unique exhibits at the Natural History Museum of Los Angeles County.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from St. Louis, MO to Los Angeles, CA
Most popular bus connections from St. Louis, MO
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