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The cheapest and fastest buses from St. Louis, MO to Louisville, KY
Showing times and prices for Apr 04
Cheapest price
$74
Average price
$92
Fastest journey
7 h 5 m
Average duration
10 h 21 m
Buses per day
6
Distance
389 km
Cheap tickets
The best way to find a cheap bus ticket from St. Louis, MO to Louisville, KY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Louisville, KY will cost around $92 if you buy it on the day, but the cheapest tickets can be found for only $74.
Fast buses
It's difficult to get from St. Louis, MO to Louisville, KY without transferring at least once.
FlixBus+
11:30 PM12h45St. Louis, S 15th St (Civic center)1:15 PMLouisville, W Broadway (Greyhound Bus Station), KY$741One-way1 transfer- undefined · undefined1:55 PM7h05St. Louis, S 15th St (Civic center)10:00 PMLouisville, W Broadway (Greyhound Bus Station), KY$741One-way1 transfer
- undefined · undefined8:45 AM8h15St. Louis, S 15th St (Civic center)6:00 PMLouisville, W Broadway (Greyhound Bus Station), KY$741One-way1 transfer
- FlixBus+11:45 PM13h25St. Louis, S 15th St (Civic center)2:10 PMLouisville, W Broadway (Greyhound Bus Station), KY$761One-way1 transfer
- undefined · undefined2:00 AM10h15St. Louis, S 15th St (Civic center)1:15 PMLouisville, W Broadway (Greyhound Bus Station), KY$981One-way1 transfer
- undefined · undefined1:55 PM7h05St. Louis, S 15th St (Civic center)10:00 PMLouisville, W Broadway (Greyhound Bus Station), KY$741One-way1 transfer
- undefined · undefined8:45 AM8h15St. Louis, S 15th St (Civic center)6:00 PMLouisville, W Broadway (Greyhound Bus Station), KY$741One-way1 transfer
- undefined · undefined2:00 AM10h15St. Louis, S 15th St (Civic center)1:15 PMLouisville, W Broadway (Greyhound Bus Station), KY$981One-way1 transfer
- FlixBus+11:30 PM12h45St. Louis, S 15th St (Civic center)1:15 PMLouisville, W Broadway (Greyhound Bus Station), KY$741One-way1 transfer
- FlixBus+11:45 PM13h25St. Louis, S 15th St (Civic center)2:10 PMLouisville, W Broadway (Greyhound Bus Station), KY$761One-way1 transfer
Travel Information
Compare bus, train, and flight for St. Louis, MO to Louisville, KY
Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Louisville, KY among Omio's users. If you are prioritising price take the bus with prices starting from $52. For those with little time consider booking a flight which can get you there in 6h 3m. The ticket price range depends on the travel mode: a bus costs an average of $52, and a flight costs an average of $173.
Distance: 241 miles (389 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
$68 Average price Cheapest | $315 Average price | $141 Average price |
9h 48m Average total duration 9h 18m Onboard + 30m Additional time* | 9h 3m Average total duration Fastest 6h 3m Onboard + 3h 0m Additional time* | 20h 53m Average total duration 20h 23m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
St. Louis, MO to Louisville, KY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 01:15PM | Duration 10h15 | Departure days Sat | Cheapest price $98 |
Operator Greyhound | Departure Time 08:45AM | Arrival Time 06:00PM | Duration 8h15 | Departure days Sat | Cheapest price $74 |
Operator Greyhound | Departure Time 01:55PM | Arrival Time 10:00PM | Duration 7h05 | Departure days Sat | Cheapest price $74 |
Operator Amtrak | Departure Time 02:55PM | Arrival Time 05:35AM | Duration 13h40 | Departure days Sat | Cheapest price $156 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 01:15PM | Duration 12h45 | Departure days Sat | Cheapest price $74 |
Operator FlixBus | Departure Time 11:45PM | Arrival Time 02:10PM | Duration 13h25 | Departure days Sat | Cheapest price $76 |
Live departures
St. Louis, MO to Louisville, KY bus times
The table below shows live departures for St. Louis, MO to Louisville, KY buses for tomorrow, Friday, April 3. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| undefined · undefined | 7:00 AM St. Louis, S 15th St (Civic center) | 10h15 | 5:15 PM Louisville, W Broadway (Greyhound Bus Station), KY | 1 transfer | |
| undefined · undefined | 1:45 PM St. Louis, S 15th St (Civic center) | 8h15 | 10:00 PM Louisville, W Broadway (Greyhound Bus Station), KY | 1 transfer | |
| undefined · undefined | 6:55 PM St. Louis, S 15th St (Civic center) | 7h05 | 2:00 AM Louisville, W Broadway (Greyhound Bus Station), KY | 1 transfer | |
 318 Lincoln Service Missouri River Runner · 8856 AMTRAK | 7:55 PM St. Louis Station, St. Louis, MO | 13h40 | 9:35 AM Louisville, KY | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Louisville, KY by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book St. Louis, MO to Louisville, KY buses with Omio?
Greyhound operates all buses services from St. Louis, MO to Louisville, KY.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Louisville, KY.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from St. Louis, MO to Louisville, KY.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from St. Louis, MO to Louisville, KY.
Journey information
Overview: Bus from St. Louis, MO to Louisville, KY
USAUSA
Buses from St. Louis, MO to Louisville, KY run on average 4 times per day, taking around 9h 18m. Cheap bus tickets for this journey start at $52 (€42) if you book in advance.
The earliest bus runs at 02:00, the last at 23:30. The fastest bus covers the 241 miles (389 km) distance in 10h 25m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 241 miles (389 km) |
Average bus duration 9h 18m |
Cheapest ticket price $52 (€42) |
Buses per day 4 |
Fastest bus 10h 25m |
First bus 2:00 AM |
Last bus 11:30 PM |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from St. Louis, MO to Louisville, KYYou can travel by bus between St. Louis, MO to Louisville, KY with Greyhound for as low as $52 (€42). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
10h 25m
Cheapest Price
$61 (€50)
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
FAQs: Bus from St. Louis, MO to Louisville, KY
Find answers to the most common questions about traveling from St. Louis, MO to Louisville, KY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.
Cheap bus tickets from St. Louis, MO to Louisville, KY can start from as little as $52 (€42) when you book in advance. The average bus ticket price for St. Louis, MO to Louisville, KY is $68 (€55) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Louisville, KY is 10h 25m to travel the 241 miles (389 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Louisville, KY leaves at 2:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Louisville, KY leaves at 11:30 PM.
There are 4 buses a day from St. Louis, MO to Louisville, KY which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to Louisville, KY, you can count on Greyhound for the best way to get you to Louisville, KY. You can also check all possible bus companies who offer a service between St. Louis, MO and Louisville, KY and compare the amenities they offer before buying a bus ticket.
A trip to Louisville, KY from St. Louis, MO is worth doing but not as a day trip with a journey time of 10h 25m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to Louisville, KY is December.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Louisville, KY including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Louisville, KY:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to Louisville, KY for bus company Greyhound.
Whether you can cancel your bus ticket from St. Louis, MO to Louisville, KY depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Louisville, KY.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Louisville, KY:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Louisville, KY:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from St. Louis, MO to Louisville, KY.
You can reserve your seat on the bus from St. Louis, MO to Louisville, KY with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from St. Louis, MO to Louisville, KY with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from St. Louis, MO to Louisville, KY with the following bus company: Greyhound.
Since neither St. Louis, MO nor Louisville, KY are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Louisville, KY among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Louisville, KY, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and around popular attractions. Scams involving overcharging by taxi or ride-share drivers can occur, so using reputable services and confirming fares upfront is advised. Travelers should also be aware of distracted driver risks and practice standard safety precautions at night. Staying vigilant and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from St. Louis, MO to Louisville, KY
St. Louis
Louisville
The major bus station for departures in St. Louis is St. Louis, S 15th St (Civic center). Find all the information you need to know about services, amenities and connections at St. Louis, S 15th St (Civic center) for your trip from St. Louis to Louisville.
St. Louis, S 15th St (Civic center)
information
The major bus station for arrivals in Louisville is Louisville, W Broadway (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Louisville, W Broadway (Greyhound Bus Station) for your trip to Louisville from St. Louis.
Louisville, W Broadway (Greyhound Bus Station)
information
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Louisville, KY
Here are some other resources that might have the information you need
Most popular buses to and from Louisville, KY and St. Louis, MO
Most popular bus connections to Louisville, KY
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