The cheapest and fastest buses from San Antonio, TX to Louisville, KY
Cheapest price
$325
Average price
$325
Fastest journey
1 d 1 h 25 m
Average duration
1 d 1 h 25 m
Buses per day
1
Distance
1529 km
The best way to find a cheap bus ticket from San Antonio, TX to Louisville, KY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Louisville, KY will cost around $325 if you buy it on the day, but the cheapest tickets can be found for only $325.
It's difficult to get from San Antonio, TX to Louisville, KY without transferring at least 2 times.
1:30 AM25h25San Antonio, TX2:55 AMLouisville, KY$3251One-way2 transfers
1:30 AM25h25San Antonio, TX2:55 AMLouisville, KY$3251One-way2 transfers
San Antonio, TX to Louisville, KY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:30AM | Arrival Time 01:30AM | Duration 23h00 | Departure days Sat | Cheapest price $401 |
Operator Greyhound | Departure Time 05:50AM | Arrival Time 09:35AM | Duration 26h45 | Departure days Sat | Cheapest price $256 |
Operator Greyhound | Departure Time 07:45AM | Arrival Time 06:00PM | Duration 33h15 | Departure days Sat | Cheapest price $258 |
Operator Greyhound | Departure Time 12:35PM | Arrival Time 02:10PM | Duration 24h35 | Departure days Sat | Cheapest price $282 |
Operator Greyhound | Departure Time 09:15PM | Arrival Time 01:30AM | Duration 27h15 | Departure days Sat | Cheapest price $318 |
Live departures
San Antonio, TX to Louisville, KY bus times
The table below shows live departures for San Antonio, TX to Louisville, KY buses for today, Saturday, April 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
undefined · undefined · undefined | 6:30 AM San Antonio, N St Mary's St (Greyhound), TX | 23h00 | 5:30 AM Louisville, W Broadway (Greyhound Bus Station), KY | 2 transfers | |
undefined · undefined · undefined | 10:50 AM San Antonio, N St Mary's St (Greyhound), TX | 26h45 | 1:35 PM Louisville, W Broadway (Greyhound Bus Station), KY | 2 transfers | |
FlixBus · FlixBus+ undefined · undefined | 12:45 PM San Antonio, Avenue A / Pearl Pkwy, TX | 33h15 | 10:00 PM Louisville, W Broadway (Greyhound Bus Station), KY | 4 transfers | |
undefined · undefined · undefined | 5:35 PM San Antonio, N St Mary's St (Greyhound), TX | 24h35 | 6:10 PM Louisville, W Broadway (Greyhound Bus Station), KY | 2 transfers | |
| Sunday, April 5 | |||||
![]() | 1:30 AM San Antonio, TX | 25h25 | 2:55 AM Louisville, KY | 2 transfers | |
+ undefined · undefined | 2:15 AM San Antonio, N St Mary's St (Greyhound), TX | 27h15 | 5:30 AM Louisville, W Broadway (Greyhound Bus Station), KY | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Antonio, TX to Louisville, KY by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 05
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Apr 11
Why should you book San Antonio, TX to Louisville, KY buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from San Antonio, TX to Louisville, KY
Take a bus from San Antonio, TX to Louisville, KY and enjoy the approximately 950 miles (1529 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 01:30, the last at 23:00.
Distance 950 miles (1529 km) |
Average bus duration 21h 45m |
Buses per day 6 |
First bus 1:30 AM |
Last bus 11:00 PM |
Bus providers: Greyhound from San Antonio, TX to Louisville, KYYou can travel by bus between San Antonio, TX to Louisville, KY with Greyhound. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from San Antonio, TX to Louisville, KY
Find answers to the most common questions about traveling from San Antonio, TX to Louisville, KY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from San Antonio, TX to Louisville, KY
Most popular bus connections from San Antonio, TX
More options for your journey from San Antonio, TX to Louisville, KY
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