Tampa, FL to Greenville, SC bus

Fri, Apr 03
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Costa Verde
Rede Expressos
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Costa Verde
Rede Expressos
2,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

Travel Information

Compare bus, train, and flight for Tampa, FL to Greenville, SC

Omio recommends booking the flight as it is the most popular option from Tampa, FL to Greenville, SC among Omio's users. If you are prioritising price take the flight with prices starting from $54. For those with little time consider booking a flight which can get you there in 1h 29m. The ticket price range depends on the travel mode: a flight costs an average of $54, and a train costs an average of $139.

Distance: 477 miles (768 km)

Compare bus with

Bus
Most popular
Flight
Train

$179

Average price

$130

Average price

Cheapest

$275

Average price

19h 45m

Average total duration

19h 15m

Onboard

+

30m

Additional time*

4h 29m

Average total duration

Fastest

1h 29m

Onboard

+

3h 0m

Additional time*

22h 37m

Average total duration

22h 7m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Direct Options

Live departures

Tampa, FL to Greenville, SC bus times

The table below shows live departures for Tampa, FL to Greenville, SC buses for today, Friday, April 3. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus10:55 PM Tampa, FL
13h05
12:00 PM Greenville, SC0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Tampa, FL to Greenville, SC by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Apr 04
Sun
Apr 05
Mon
Apr 06
Tue
Apr 07
Wed
Apr 08
Thu
Apr 09
Fri
Apr 10

Journey information

Overview: Bus from Tampa, FL to Greenville, SC

USAUSA
USAUSA
Icon of bus

Buses from Tampa, FL to Greenville, SC run on average 6 times per day, taking around 19h 15m. Cheap bus tickets for this journey start at $111 (€90) but you can travel from only $54 (€44) by flight.

The earliest bus runs at 02:23, the last at 22:35. The fastest bus covers the 477 miles (768 km) distance in 13h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $54 (€44)
Distance
477 miles (768 km)
Average bus duration
19h 15m
Cheapest ticket price
$111 (€90)
Buses per day
6
Fastest bus
13h 5m
First bus
2:23 AM
Last bus
10:35 PM
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $54 (€44)

FAQs: Bus from Tampa, FL to Greenville, SC

Find answers to the most common questions about traveling from Tampa, FL to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Tampa, FL to Greenville, SC can start from as little as $111 (€90) when you book in advance. The average bus ticket price for Tampa, FL to Greenville, SC is $179 (€146) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Tampa, FL to Greenville, SC is 13h 5m to travel the 477 miles (768 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Tampa, FL to Greenville, SC leaves at 2:23 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Tampa, FL to Greenville, SC leaves at 10:35 PM.
A trip to Greenville, SC from Tampa, FL is worth doing but not as a day trip with a journey time of 13h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Tampa, FL to Greenville, SC is July.
It's helpful to compare your options as there are 3 ways to travel between Tampa, FL and Greenville, SC including taking a bus, train, and flight.
No, the bus from Tampa, FL to Greenville, SC has no accessibility options.
No, there are no bathrooms on board the bus from Tampa, FL to Greenville, SC.
No, bikes are not allowed on board the bus from Tampa, FL to Greenville, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Tampa, FL to Greenville, SC.
No, luggage for the bus from Tampa, FL to Greenville, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Tampa, FL to Greenville, SC.
Unfortunately, pets are not allowed on the bus from Tampa, FL to Greenville, SC.
No, there are no USB plugs on board the bus from Tampa, FL to Greenville, SC.
No, there is no WiFi on board the bus from Tampa, FL to Greenville, SC.
Since neither Tampa, FL nor Greenville, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Tampa, FL to Greenville, SC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Greenville, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and popular events. Common scams include overcharging by unofficial taxi or ride-share drivers and fake charity solicitations. It is advisable to use authorized transportation services, avoid displaying valuables openly, and stay aware of surroundings, particularly at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Tampa, FL to Greenville, SC

Tampa
Greenville
The major bus station for departures in Tampa is Tampa, Marion Transit Center. Find all the information you need to know about services, amenities and connections at Tampa, Marion Transit Center for your trip from Tampa to Greenville.
Tampa, Marion Transit Center
information
Tampa, USF Holly Drive (Central Plant)
information

More options for your journey from Tampa, FL to Greenville, SC

Here are some other resources that might have the information you need

Return journeys for buses from Greenville, SC to Tampa, FL
Flights from Tampa, FL to Greenville, SC
Tickets and more information for coaches to Tampa, FL
Tickets and more information for coaches to Greenville, SC

Most popular buses to and from Greenville, SC and Tampa, FL

Bus Tampa, FL - Boston, MA
Bus Tampa, FL - New York, NY
Bus Tampa, FL - Los Angeles, CA
Bus Tampa, FL - Chicago, IL
Bus Tampa, FL - Washington, DC
Bus Tampa, FL - San Diego, CA
Bus Tampa, FL - Philadelphia, PA
Bus Tampa, FL - Dallas, TX
Bus Tampa, FL - Orlando, FL
Bus Tampa, FL - Atlanta, GA
Bus Tampa, FL - San Francisco, CA
Bus Tampa, FL - Phoenix, AZ
Bus Tampa, FL - Miami, FL
Bus Tampa, FL - Las Vegas, NV
Bus Tampa, FL - Houston, TX
Bus Tampa, FL - Sacramento, CA
Bus Tampa, FL - Portland, OR
Bus Tampa, FL - Baltimore, MD
Bus Tampa, FL - San Antonio, TX
Bus Tampa, FL - Newark, NJ
Bus Tampa, FL - Denver, CO
Bus Tampa, FL - New Orleans, LA
Bus Boston, MA - Greenville, SC
Bus New York, NY - Greenville, SC
Bus Chicago, IL - Greenville, SC
Bus Washington, DC - Greenville, SC
Bus Philadelphia, PA - Greenville, SC
Bus Orlando, FL - Greenville, SC
Bus Atlanta, GA - Greenville, SC
Bus Miami, FL - Greenville, SC
Bus Houston, TX - Greenville, SC
Bus Sacramento, CA - Greenville, SC
Bus Portland, OR - Greenville, SC
Bus Baltimore, MD - Greenville, SC
Bus Newark, NJ - Greenville, SC
Bus Austin, TX - Greenville, SC
Bus Charlotte, NC - Greenville, SC
Bus Nashville, TN - Greenville, SC
Bus Raleigh, NC - Greenville, SC
Bus Indianapolis, IN - Greenville, SC
Bus Richmond, VA - Greenville, SC
Bus Fort Lauderdale, FL - Greenville, SC
Bus Columbus, OH - Greenville, SC
Bus Detroit, MI - Greenville, SC
HomeBusesBuses in USABus tickets to Greenville, SCTampa, FL to Greenville, SC bus

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone