The cheapest and fastest trains from Boston, MA to St. Louis, MO
Cheapest price
$486
Average price
$1381
Fastest journey
1 d 7 h 28 m
Average duration
1 d 7 h 29 m
Trains per day
10
Distance
1667 km
The best way to find a cheap train ticket from Boston, MA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Boston, MA to St. Louis, MO will cost around $1381 if you buy it on the day, but the cheapest tickets can be found for only $486.
It's difficult to get from Boston, MA to St. Louis, MO without transferring at least once.
449 Lake Shore Limited · 49 Lake Shore Limited · 21 Texas Eagle12:57 PM31h28Back Bay station, Boston, MA7:25 PMSt. Louis Station, St. Louis, MO$4861One-way2 transfers
449 Lake Shore Limited · 49 Lake Shore Limited · 21 Texas Eagle12:50 PM31h35South Station, Boston, MA7:25 PMSt. Louis Station, St. Louis, MO$4861One-way2 transfers
449 Lake Shore Limited · 49 Lake Shore Limited · 421 Texas Eagle12:50 PM31h35South Station, Boston, MA7:25 PMSt. Louis Station, St. Louis, MO$4861One-way2 transfers
449 Lake Shore Limited · 49 Lake Shore Limited · 421 Texas Eagle12:57 PM31h28Back Bay station, Boston, MA7:25 PMSt. Louis Station, St. Louis, MO$4861One-way2 transfers
449 Lake Shore Limited · 307 Lincoln Service12:57 PM36h12Back Bay station, Boston, MA12:09 AMSt. Louis Station, St. Louis, MO$18011One-way1 transfer
449 Lake Shore Limited · 49 Lake Shore Limited · 21 Texas Eagle12:57 PM31h28Back Bay station, Boston, MA7:25 PMSt. Louis Station, St. Louis, MO$4861One-way2 transfers
449 Lake Shore Limited · 49 Lake Shore Limited · 421 Texas Eagle12:57 PM31h28Back Bay station, Boston, MA7:25 PMSt. Louis Station, St. Louis, MO$4861One-way2 transfers
449 Lake Shore Limited · 21 Texas Eagle12:57 PM31h28Back Bay station, Boston, MA7:25 PMSt. Louis Station, St. Louis, MO$20411One-way1 transfer
449 Lake Shore Limited · 421 Texas Eagle12:57 PM31h28Back Bay station, Boston, MA7:25 PMSt. Louis Station, St. Louis, MO$20901One-way1 transfer
449 Lake Shore Limited · 49 Lake Shore Limited · 21 Texas Eagle12:50 PM31h35South Station, Boston, MA7:25 PMSt. Louis Station, St. Louis, MO$4861One-way2 transfers
Travel Information
Compare train, bus, and flight for Boston, MA to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Boston, MA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $101. For those with little time consider booking a flight which can get you there in 3h 54m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.5 - 1.5kg. The ticket price range depends on the travel mode: a bus costs an average of $101, and a train costs an average of $121.
Distance: 1035 miles (1667 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
$458 Average price | $397 Average price | $213 Average price Cheapest |
27h 55m Average total duration 27h 25m Onboard + 30m Additional time* | 6h 54m Average total duration Fastest 3h 54m Onboard + 3h 0m Additional time* | 27h 58m Average total duration 27h 28m Onboard + 30m Additional time* |
0.5 - 1.5kg CO2 emissions Lowest | 5.0 - 10.0kg CO2 emissions | 1.7 - 4.2kg CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Boston, MA to St. Louis, MO train times
The table below shows live departures for Boston, MA to St. Louis, MO trains for today, Wednesday, April 1. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
449 Lake Shore Limited · 49 Lake Shore Limited · 21 Texas Eagle | 4:50 PM South Station, Boston, MA | 31h35 | 12:25 AM St. Louis Station, St. Louis, MO | 2 transfers | |
449 Lake Shore Limited · 49 Lake Shore Limited · 21 Texas Eagle | 4:57 PM Back Bay station, Boston, MA | 31h28 | 12:25 AM St. Louis Station, St. Louis, MO | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Boston, MA to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 02
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Apr 08
Journey information
Overview: Train from Boston, MA to St. Louis, MO
Trains from Boston, MA to St. Louis, MO run on average 7 times per day, taking around 27h 25m. Cheap train tickets for this journey start at $121 (€98) but you can travel from only $101 (€82) by bus.
The earliest train runs at 08:10, the last at 14:55. The fastest train covers the 1035 miles (1667 km) distance in 31h 10m.
Distance 1035 miles (1667 km) |
Average train duration 27h 25m |
Cheapest ticket price $121 (€98) |
Trains per day 7 |
Fastest train 31h 10m |
First train 8:10 AM |
Last train 2:55 PM |
Train companies: Amtrak from Boston, MA to St. Louis, MO trainsAmtrak trains will get you between Boston, MA and St. Louis, MO from $101 (€82). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Boston, MA to St. Louis, MO
Find answers to the most common questions about traveling from Boston, MA to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Boston, MA to St. Louis, MO
- 5:00 AM - 11:00 PM Monday - Sunday
- Free
- The car park is open 24/7. Access via Atlantic Avenue.
- Legal Sea Foods
- Tavern in the Square
- Outside the main entrance.
- Elevators, restrooms.
- $0.50
- InterContinental Boston
- The Langham, Boston
- Boston Harbor Hotel
- Located in the main hall
- Avis
- Budget
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-5 for Amtrak services
- Hall 2: platforms 6-13 for MBTA Commuter Rail services
- Bus terminal located on the upper level.
- Subway: Red Line
- Bus: Several lines available
- Commuter Rail: Multiple lines
- 5:00 AM - 1:00 AM Monday - Sunday
- Free
- Parking is available nearby with several garages in the vicinity.
- Sorellina
- Atlantic Fish Company
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $0.50
- Copley Square Hotel
- The Westin Copley Place
- Fairmont Copley Plaza
- Located in the main hall
- Avis
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-3 for Amtrak and MBTA Commuter Rail
- Hall 2: Orange Line subway platforms
- Subway: Orange Line
- Bus: Several lines available
- Commuter Rail: Framingham/Worcester Line, Franklin Line, Needham Line, Providence/Stoughton Line
- 5:30 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available on-site with both short-term and long-term options.
- Landry's Seafood House
- The Station Grille
- Outside the main entrance.
- Ramps, restrooms.
- $1
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Courtyard St. Louis Downtown West
- Drury Inn St. Louis at Union Station
- Located in the main hall
- Avis
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for Amtrak and regional trains
- Hall 2: MetroLink connections
- MetroLink: Red Line, Blue Line
- Bus: Several lines available including 40, 94, 97
Most popular train connections from Boston, MA
More options for your journey from Boston, MA to St. Louis, MO
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