The cheapest and fastest trains from Brussels to Prague
Cheapest price
$133
Average price
$344
Fastest journey
11 h 56 m
Average duration
12 h 10 m
Trains per day
5
Distance
717 km
The best way to find a cheap train ticket from Brussels to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brussels to Prague will cost around $344 if you buy it on the day, but the cheapest tickets can be found for only $133.
It's difficult to get from Brussels to Prague without transferring at least 2 times.
ICE 15 · ICE 2513 · rj 17910:25 AM13h06Brussels-Midi11:31 PMPrague hlavní nádraží$1331One-way2 transfers
ICE 13 · ICE 623 · 3571+
3618:25 AM11h56Brussels-Midi8:21 PMPrague hlavní nádraží$3361One-way3 transfers
ICE 15 · ICE 627 · 3597+
36310:25 AM11h57Brussels-Midi10:22 PMPrague hlavní nádraží$4111One-way3 transfers
ICE 13 · ICE 623 · R 3571 · EC 3618:25 AM11h56Brussels-Midi8:21 PMPrague hlavní nádraží$4211One-way3 transfers
ICE 15 · ICE 627 · R 3595 · EC 36310:25 AM11h57Brussels-Midi10:22 PMPrague hlavní nádraží$4211One-way3 transfers
ICE 13 · ICE 623 · 3571+
3618:25 AM11h56Brussels-Midi8:21 PMPrague hlavní nádraží$3361One-way3 transfers
ICE 13 · ICE 623 · R 3571 · EC 3618:25 AM11h56Brussels-Midi8:21 PMPrague hlavní nádraží$4211One-way3 transfers
ICE 15 · ICE 627 · 3597+
36310:25 AM11h57Brussels-Midi10:22 PMPrague hlavní nádraží$4111One-way3 transfers
ICE 15 · ICE 627 · R 3595 · EC 36310:25 AM11h57Brussels-Midi10:22 PMPrague hlavní nádraží$4211One-way3 transfers
ICE 15 · ICE 2513 · rj 17910:25 AM13h06Brussels-Midi11:31 PMPrague hlavní nádraží$1331One-way2 transfers
Travel Information
Compare train, bus, and flight for Brussels to Prague
Omio recommends booking the flight as it is the most popular option from Brussels to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $50. For those with little time consider booking a flight which can get you there in 2h 6m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $50, and a flight costs an average of $25.
Distance: 445 miles (717 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
$143 Average price | $143 Average price | $82 Average price Cheapest |
13h 15m Average total duration 12h 45m Onboard + 30m Additional time* | 5h 6m Average total duration Fastest 2h 6m Onboard + 3h 0m Additional time* | 15h 58m Average total duration 15h 28m Onboard + 30m Additional time* |
0.2 - 0.6kg CO2 emissions Lowest | 2.2 - 4.3kg CO2 emissions | 0.7 - 1.8kg CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Brussels to Prague train times
The table below shows live departures for Brussels to Prague trains for today, Wednesday, April 1. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
ICE 315 · ICE 721 · Bus EV · 3835 | On time 10:25 AM Brussels-Midi | 18h56 | 5:21 AM Prague hlavní nádraží | 5 transfers | |
ICE 17 · ICE 2517 · S 31701 · Os 28018 | On time 12:25 PM Brussels-Midi | 17h45 | 6:10 AM Prague hlavní nádraží | 4 transfers | |
ICE 17 · ICE 2517 · S1 · 28018 | On time 12:25 PM Brussels-Midi | 17h45 | 6:10 AM Prague hlavní nádraží | 4 transfers | |
ICE 317 · ICE 592 · 16501 · S1 | On time 2:22 PM Brussels-Midi | 16h48 | 7:10 AM Prague hlavní nádraží | 5 transfers | |
ICE 19 · ICE 590 · EC 459 | On time 4:25 PM Brussels-Midi | 15h00 | 7:25 AM Prague hlavní nádraží | 2 transfers | |
453 | 5:22 PM Brussels-Midi | 15h29 | 8:51 AM Prague hlavní nádraží | 0 transfersDirect | |
| Thursday, April 2 | |||||
ICE 13 · ICE 623 · R 3571 · EC 361 | On time 6:25 AM Brussels-Midi | 11h56 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 13 · ICE 623 · 3571+ 361 | On time 6:25 AM Brussels-Midi | 11h56 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 15 · ICE 627 · R 3595 · EC 363 | 8:25 AM Brussels-Midi | 11h57 | 8:22 PM Prague hlavní nádraží | 3 transfers | |
ICE 15 · ICE 2513 · rj 179 | 8:25 AM Brussels-Midi | 13h06 | 9:31 PM Prague hlavní nádraží | 2 transfers | |
ICE 15 · ICE 627 · 3597+ 363 | 8:25 AM Brussels-Midi | 11h57 | 8:22 PM Prague hlavní nádraží | 3 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Brussels to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 01
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Why should you book Brussels to Prague trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of Alibus, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH or European Sleeper to find the best option for your trip from Brussels to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Brussels to Prague.
Why book with Omio over Trainline, Wanderu or Raileurope?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Alibus, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH or European Sleeper to find the best option for your trip from Brussels to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Brussels to Prague.
How far in advance should I book train tickets from Brussels to Prague?
Journey information
Overview: Train from Brussels to Prague
Trains from Brussels to Prague run on average 6 times per day, taking around 12h 45m. Cheap train tickets for this journey start at $19 (€15) if you book in advance.
The earliest train runs at 00:20, the last at 23:58. The fastest train covers the 445 miles (717 km) distance in 10h 41m.
Distance 445 miles (717 km) |
Average train duration 12h 45m |
Cheapest ticket price $19 (€15) |
Trains per day 6 |
Fastest train 10h 41m |
First train 12:20 AM |
Last train 11:58 PM |
Train companies: Deutsche Bahn, Alibus, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH, European Sleeper from Brussels to Prague trainsDeutsche Bahn, Alibus, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH, European Sleeper trains will get you between Brussels and Prague from $19 (€15). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Alibus
alex-Länderbahn und Vogtlandbahn-GmbH
České dráhy
European Sleeper
FAQs: Trains from Brussels to Prague
Find answers to the most common questions about traveling from Brussels to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Brussels to Prague
- Mon - Sun: 05:45 - 21:30
- Wi-Fi is available for a fee.
- Baggage storage facility is located across from the Thalys business lounge.
- Pullman Hotel Bar
- Quick Gare du Midi
- Subway
- EXKi Zuid
- Starbucks
- Häagen-Dazs
- Sbarro
- The Coffee Club
- The Belgian Chocolate House
- PAUL
- & many more
- Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
- Les Lofts De Styliste
- Park Inn by Radisson Brussels Midi
- Pullman Brussels Centre Midi
- Located in the main concourse and next to the international platforms.
- Mon - Sun: 06:15 - 22:00
- Free Wi-Fi available in Starbucks.
- Luggage lockers are located on Level 0 near Platforms 1 and 2.
- Starbucks
- Brasserie 28 Brewery
- Panos
- Delitraiteur Eat & Go
- Station has a wide range of facilities for passengers with limited mobility: elevators and escalators to platforms, wheelchair lifts and mobile ramps, barrier-free toilets and accessible parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
- Hilton Brussels Grand Palace
- Hotel NH Brussels Carrefour de l'Europe
- Hôtel The Moon
- Mon - Sun: 06:15 - 22:00
- Travel Center / information desk is located on the left side from the main entrance.
- Metro lines: 1, 5
- Train lines: IC, Intercity Direct 9200, RER (S1, S2, S3, S6, S8, S10)
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
- Restaurant Fantova Kavárna
- Sushi Time
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
- Cost CZK 100
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Partyzánská street.
- Restaurant Na Kovárně
- Cross Club
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
- Located in the main hall
- Avis
- Budget
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking options.
- Restaurant Kotleta
- Café Imperial
- Outside the main entrance.
- Ramps.
- CZK 10
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
More options for your journey from Brussels to Prague
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