Des Moines, IA to St. Louis, MO train

Sat, Apr 04
+ Add return
Regionale
Deutsche Bahn
iryo
Frecciarossa
Italo
2,000+ travel companies
Regionale
Deutsche Bahn
iryo
Frecciarossa
Italo
2,000+ travel companies
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Travel Information

Compare bus and flight for Des Moines, IA to St. Louis, MO

Omio recommends booking the flight as it is the most popular option from Des Moines, IA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $136. For those with little time consider booking a flight which can get you there in 2h 51m. The ticket price range depends on the travel mode: a bus costs an average of $136, and a flight costs an average of $192.

Distance: 273 miles (440 km)

Compare flight with

Most popular
Flight
Bus

$301

Average price

$169

Average price

Cheapest

5h 51m

Average total duration

Fastest

2h 51m

Onboard

+

3h 0m

Additional time*

14h 15m

Average total duration

13h 45m

Onboard

+

30m

Additional time*

United

Most popular airline

Greyhound

Most popular bus company

Direct Options

Direct Options

Compare prices and tickets Des Moines, IA to St. Louis, MO by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Apr 04
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Journey information

Overview: Train from Des Moines, IA to St. Louis, MO

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Take a train from Des Moines, IA to St. Louis, MO and enjoy the approximately 273 miles (440 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $136 (€111)
Distance
273 miles (440 km)
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $136 (€111)

FAQs: Trains from Des Moines, IA to St. Louis, MO

Find answers to the most common questions about traveling from Des Moines, IA to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

FAQs
The distance by train from Des Moines, IA to St. Louis, MO is 273 miles (440 km).
Unfortunately, there is no night train available from Des Moines, IA to St. Louis, MO.
The cheapest way to get from Des Moines, IA to St. Louis, MO is by bus, with a cost of around $136 (€111).
The train journey from Des Moines, IA to St. Louis, MO offers a varied landscape, with views of the rolling hills of Iowa and the rural charm of the Midwest. While it may not be considered traditionally "scenic" like mountainous or coastal routes, it provides a pleasant and peaceful experience with glimpses of small towns and open farmland.
Three days are typically sufficient to explore key attractions in St. Louis, including the Gateway Arch, Forest Park, and the Missouri Botanical Garden.
No, you cannot take the train from Des Moines, IA to St. Louis, MO.
Since neither Des Moines, IA nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
Popular day trips by train from St. Louis, MO include Springfield, IL, Hermann, MO, Washington, MO, Alton, IL, Carlinville, IL.
We recommend using the flight as it is the most popular way to get from Des Moines, IA to St. Louis, MO among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

More options for your journey from Des Moines, IA to St. Louis, MO

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HomeTrainsTrains in USATrain Times to St. Louis, MODes Moines, IA to St. Louis, MO train

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