The cheapest and fastest trains from Pisa Centrale to Milan Centrale
Cheapest price
$30
Average price
$63
Fastest journey
3 h 18 m
Average duration
3 h 21 m
Trains per day
42
Distance
219 km
The best way to find a cheap train ticket from Pisa Centrale to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa Centrale to Milan Centrale will cost around $63 if you buy it on the day, but the cheapest tickets can be found for only $30.
Of the 42 trains that leave Pisa Centrale for Milan Centrale on Sun, Apr 05, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Apr 05 the direct trains cover the 219 km distance in an average of 3 h 21 m but if you time it right, some trains will get you there in just 3 h 18 m .
On Sun, Apr 05 the slowest trains will take 3 h 23 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale TRENORD 10502 · Regionale Veloce TTPER 24865:42 PM5h07Pisa Centrale10:49 PMMilan Centrale$301One-way1 transfer
Regionale 2294 · Regionale Veloce TTPER 24625:48 AM5h01Pisa Centrale10:49 AMMilan Centrale$301One-way1 transfer
Regionale 22966:45 PM4h41Pisa Centrale11:26 PMMilan Centrale$301One-way0 transfers
Regionale 2294 · Regionale TRENORD 23625:48 AM4h47Pisa Centrale10:35 AMMilan Centrale$301One-way1 transfer
Regionale TRENORD 10502 · Regionale TRENORD 21865:42 PM4h58Pisa Centrale10:40 PMMilan Centrale$301One-way1 transfer
ETRUSCHI LINE 18276+
FRECCIAROSSA 95168:32 AM3h18Pisa Centrale11:50 AMMilan Centrale$871One-way1 transfer
Regionale Veloce 4012+
FRECCIAROSSA 95127:30 AM3h20Pisa Centrale10:50 AMMilan Centrale$871One-way1 transfer
Tuscany Line 4052+
FRECCIAROSSA 1000 95566:29 PM3h21Pisa Centrale9:50 PMMilan Centrale$871One-way1 transfer
Tuscany Line 4038+
FRECCIAROSSA 95402:27 PM3h23Pisa Centrale5:50 PMMilan Centrale$871One-way1 transfer
TUSCANY LINE 19498+
FRECCIAROSSA 95841:27 PM3h23Pisa Centrale4:50 PMMilan Centrale$871One-way1 transfer
Travel Information
Compare train and bus for Pisa Centrale to Milan Centrale
Omio recommends booking the train as it is the most popular option from Pisa Centrale to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from $15. For those with little time consider booking a train which can get you there in 3h 49m. The ticket price range depends on the travel mode: a bus costs an average of $15, and a train costs an average of $20.
Distance: 136 miles (219 km)
Compare train with
Most popular Train | Bus |
|---|---|
$31 Average price | $30 Average price Cheapest |
4h 19m Average total duration Fastest 3h 49m Onboard + 30m Additional time* | 4h 41m Average total duration 4h 11m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Pisa Centrale to Milan Centrale train times
The table below shows live departures for Pisa Centrale to Milan Centrale trains for today, Saturday, April 4. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 19382 · Regionale 12210 · Regionale Veloce 3016 | 7:40 PM Pisa Centrale | 9h55 | 5:35 AM Milan Centrale | 2 transfers | |
Intercity 522+ Regionale 12210 · Regionale Veloce 3016 | 8:53 PM Pisa Centrale | 8h42 | 5:35 AM Milan Centrale | 2 transfers | |
| Sunday, April 5 | |||||
InterCityNotte 796+ Intercity 652 | 1:26 AM Pisa Centrale | 4h59 | 6:25 AM Milan Centrale | 1 transfer | |
Regionale 18250+ FRECCIAROSSA 1000 9504 | 2:15 AM Pisa Centrale | 4h35 | 6:50 AM Milan Centrale | 1 transfer | |
Regionale 18254+ FRECCIAROSSA 1000 9400 · FRECCIAROSSA 9802 | 3:31 AM Pisa Centrale | 4h04 | 7:35 AM Milan Centrale | 2 transfers | |
Intercity 658 | 3:31 AM Pisa Centrale | 4h29 | 8:00 AM Milan Centrale | 0 transfersDirect | |
Regionale 2294 · Regionale Veloce TTPER 2462 | 3:48 AM Pisa Centrale | 5h01 | 8:49 AM Milan Centrale | 1 transfer | |
Regionale 2294 · Regionale TRENORD 2362 | 3:48 AM Pisa Centrale | 4h47 | 8:35 AM Milan Centrale | 1 transfer | |
Tuscany Line 18260+ FRECCIAROSSA 1000 9508 | 4:24 AM Pisa Centrale | 3h26 | 7:50 AM Milan Centrale | 1 transfer | |
Intercity 662 | 4:33 AM Pisa Centrale | 4h22 | 8:55 AM Milan Centrale | 0 transfersDirect | |
Regionale Veloce 4012+ FRECCIAROSSA 9512 | 5:30 AM Pisa Centrale | 3h20 | 8:50 AM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 18276+ FRECCIAROSSA 9516 | 6:32 AM Pisa Centrale | 3h18 | 9:50 AM Milan Centrale | 1 transfer | |
Intercity 666 | 6:37 AM Pisa Centrale | 5h18 | 11:55 AM Milan Centrale | 0 transfersDirect | |
TUSCANY LINE 4018+ FRECCIAROSSA 9520 | 7:09 AM Pisa Centrale | 3h41 | 10:50 AM Milan Centrale | 1 transfer | |
InterCityNotte 794+ Intercity 745 | 7:24 AM Pisa Centrale | 5h31 | 12:55 PM Milan Centrale | 1 transfer | |
FRECCIAROSSA 8606+ Intercity 666 | 7:44 AM Pisa Centrale | 4h11 | 11:55 AM Milan Centrale | 1 transfer | |
Regionale 19340 · Regionale TTPER 19246 · Regionale Veloce TTPER 2490 | 9:06 AM Pisa Centrale | 5h43 | 2:49 PM Milan Centrale | 2 transfers | |
TUSCANY LINE 4030+ FRECCIAROSSA 1000 9514 | 9:25 AM Pisa Centrale | 3h25 | 12:50 PM Milan Centrale | 1 transfer | |
Intercity 670 | 9:33 AM Pisa Centrale | 4h22 | 1:55 PM Milan Centrale | 0 transfersDirect | |
TUSCANY LINE 4032+ FRECCIAROSSA 9532 | 10:25 AM Pisa Centrale | 3h25 | 1:50 PM Milan Centrale | 1 transfer | |
Regionale 19346 · Regionale TTPER 19250 · Regionale Veloce TTPER 2478 | 10:34 AM Pisa Centrale | 6h15 | 4:49 PM Milan Centrale | 2 transfers | |
Intercity 510+ Regionale Veloce 3075 | 11:01 AM Pisa Centrale | 4h34 | 3:35 PM Milan Centrale | 1 transfer | |
Intercity 674 | 11:18 AM Pisa Centrale | 4h37 | 3:55 PM Milan Centrale | 0 transfersDirect | |
TUSCANY LINE 19498+ FRECCIAROSSA 9584 | 11:27 AM Pisa Centrale | 3h23 | 2:50 PM Milan Centrale | 1 transfer | |
Regionale 19167 · Regionale 19254 · Regionale Veloce TTPER 2482 | 11:43 AM Pisa Centrale | 7h06 | 6:49 PM Milan Centrale | 2 transfers | |
Regionale 18304+ Intercity 590 | 11:56 AM Pisa Centrale | 5h29 | 5:25 PM Milan Centrale | 1 transfer | |
Tuscany Line 4038+ FRECCIAROSSA 9540 | 12:27 PM Pisa Centrale | 3h23 | 3:50 PM Milan Centrale | 1 transfer | |
Regionale 18395+ FRECCIAROSSA 9544 | 12:46 PM Pisa Centrale | 4h04 | 4:50 PM Milan Centrale | 1 transfer | |
FRECCIABIANCA 8616+ Regionale Veloce 3079 | 12:52 PM Pisa Centrale | 4h43 | 5:35 PM Milan Centrale | 1 transfer | |
Tuscany Line 4044+ FRECCIAROSSA 9588 | 2:25 PM Pisa Centrale | 3h25 | 5:50 PM Milan Centrale | 1 transfer | |
FRECCIABIANCA 8620 | 2:46 PM Pisa Centrale | 3h54 | 6:40 PM Milan Centrale | 0 transfersDirect | |
TUSCANY LINE 4050+ FRECCIAROSSA 9552 | 3:25 PM Pisa Centrale | 3h25 | 6:50 PM Milan Centrale | 1 transfer | |
Intercity 684 | 3:31 PM Pisa Centrale | 4h24 | 7:55 PM Milan Centrale | 0 transfersDirect | |
Regionale TRENORD 10502 · Regionale TRENORD 2186 | 3:42 PM Pisa Centrale | 4h58 | 8:40 PM Milan Centrale | 1 transfer | |
Regionale TRENORD 10502 · Regionale Veloce TTPER 2486 | 3:42 PM Pisa Centrale | 5h07 | 8:49 PM Milan Centrale | 1 transfer | |
Tuscany Line 4052+ Intercity 596 | 4:29 PM Pisa Centrale | 4h48 | 9:17 PM Milan Centrale | 1 transfer | |
Tuscany Line 4052+ FRECCIAROSSA 1000 9556 | 4:29 PM Pisa Centrale | 3h21 | 7:50 PM Milan Centrale | 1 transfer | |
Regionale 2296 | 4:45 PM Pisa Centrale | 4h41 | 9:26 PM Milan Centrale | 0 transfersDirect | |
Intercity 518+ Regionale Veloce 3047 | 4:55 PM Pisa Centrale | 4h40 | 9:35 PM Milan Centrale | 1 transfer | |
TUSCANY LINE 18316 · Regionale 18236+ Intercity 1588 | 5:04 PM Pisa Centrale | 5h11 | 10:15 PM Milan Centrale | 2 transfers | |
TUSCANY LINE 4058+ FRECCIAROSSA 1000 9560 | 5:25 PM Pisa Centrale | 3h25 | 8:50 PM Milan Centrale | 1 transfer | |
Regionale 19483+ FRECCIAROSSA 9592 | 6:04 PM Pisa Centrale | 3h46 | 9:50 PM Milan Centrale | 1 transfer | |
Regionale 19483+ InterCityNotte 774 · InterCityNotte 758 | 6:04 PM Pisa Centrale | 11h01 | 5:05 AM Milan Centrale | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa Centrale to Milan Centrale by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Pisa Centrale to Milan Centrale trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Intercity, Regionale, Frecciarossa or Frecciabianca to find the best option for your trip from Pisa Centrale to Milan Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are train and bus to ensure you get the best deal for traveling from Pisa Centrale to Milan Centrale.
Journey information
Overview: Train from Pisa Centrale to Milan Centrale
Trains from Pisa Centrale to Milan Centrale run on average 40 times per day, taking around 3h 49m. Cheap train tickets for this journey start at $20 (€16) but you can travel from only $15 (€12) by bus.
There are 7 trains per day. The earliest train runs at 04:42, the last at 19:32. The fastest train covers the 136 miles (219 km) distance in 3h 18m.
Distance 136 miles (219 km) |
Average train duration 3h 49m |
Cheapest ticket price $20 (€16) |
Trains per day 40 |
Direct trains 7 |
Fastest train 3h 18m |
First train 4:42 AM |
Last train 7:32 PM |
Train companies: Italo, Intercity, Regionale, Frecciarossa, Frecciabianca, Intercity Notte, Frecciargento from Pisa Centrale to Milan Centrale trainsItalo, Intercity, Regionale, Frecciarossa, Frecciabianca, Intercity Notte, Frecciargento trains will get you between Pisa Centrale and Milan Centrale from $15 (€12). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Intercity
Regionale
Frecciarossa
Frecciabianca
Intercity Notte
Frecciargento
FAQs: Trains from Pisa Centrale to Milan Centrale
Find answers to the most common questions about traveling from Pisa Centrale to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Pisa Centrale to Milan Centrale
- Mon - Sun: 06:00 - 20:30
- There is free Wi-Fi available at the McDonald's.
- There is a luggage storage office near the end of Platform 1.
- McDonald's
- Panetteria Binario 1
- Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
- Hotel NH Pisa
- Hotel La Pace
- Hotel Maria
- Mon - Sun: 06:00 - 20:30
- Located just outside the station on Piazza Vittorio Emanuele II.
- Bus lines: 1
- Train lines: Pisamover (S2), FA, FB, IC, ICN, RV, R, EN
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Pisa Centrale
More options for your journey from Pisa Centrale to Milan Centrale
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