The cheapest and fastest trains from Rome Ostiense to Pisa Centrale
Cheapest price
$31
Average price
$60
Fastest journey
3 h 1 m
Average duration
3 h 7 m
Trains per day
25
Distance
266 km
The best way to find a cheap train ticket from Rome Ostiense to Pisa Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome Ostiense to Pisa Centrale will cost around $60 if you buy it on the day, but the cheapest tickets can be found for only $31.
Of the 25 trains that leave Rome Ostiense for Pisa Centrale on Mon, Apr 06, 11 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Apr 06 the direct trains cover the 266 km distance in an average of 3 h 7 m but if you time it right, some trains will get you there in just 3 h 1 m .
On Mon, Apr 06 the slowest trains will take 3 h 16 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
ETRUSCHI LINE 41246:23 AM3h55Rome Ostiense10:18 AMPisa Centrale$311One-way0 transfers
ETRUSCHI LINE 41342:23 PM3h52Rome Ostiense6:15 PMPisa Centrale$311One-way0 transfers
ETRUSCHI LINE 412810:23 AM3h52Rome Ostiense2:15 PMPisa Centrale$311One-way0 transfers
ETRUSCHI LINE 413212:23 PM3h52Rome Ostiense4:15 PMPisa Centrale$311One-way0 transfers
ETRUSCHI LINE 41364:23 PM4h12Rome Ostiense8:35 PMPisa Centrale$311One-way0 transfers
Intercity 5183:51 PM3h01Rome Ostiense6:52 PMPisa Centrale$481One-way0 transfers
Intercity 8227:04 PM3h04Rome Ostiense10:08 PMPisa Centrale$641One-way0 transfers
InterCityNotte 79612:15 AM3h08Rome Ostiense3:23 AMPisa Centrale$441One-way0 transfers
ETRUSCHI LINE 4131+
FRECCIARGENTO 85563:37 PM3h08Rome Ostiense6:45 PMPisa Centrale$741One-way1 transfer
InterCityNotte 7946:06 AM3h16Rome Ostiense9:22 AMPisa Centrale$441One-way0 transfers
Travel Information
Compare train and bus for Rome Ostiense to Pisa Centrale
Omio recommends booking the train as it is the most popular option from Rome Ostiense to Pisa Centrale among Omio's users. If you are prioritising price take the bus with prices starting from $14. For those with little time consider booking a train which can get you there in 3h 8m. The ticket price range depends on the travel mode: a bus costs an average of $14, and a train costs an average of $16.
Distance: 165 miles (266 km)
Compare train with
Most popular Train | Bus |
|---|---|
$28 Average price | $19 Average price Cheapest |
3h 38m Average total duration Fastest 3h 8m Onboard + 30m Additional time* | 5h 23m Average total duration 4h 53m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Rome Ostiense to Pisa Centrale train times
The table below shows live departures for Rome Ostiense to Pisa Centrale trains for today, Sunday, April 5. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Intercity 518 | 1:51 PM Rome Ostiense | 3h01 | 4:52 PM Pisa Centrale | 0 transfersDirect | |
Regionale 12551+ FRECCIAROSSA 9428+ Tuscany Line 4047 | 2:07 PM Rome Ostiense | 3h23 | 5:30 PM Pisa Centrale | 2 transfers | |
ETRUSCHI LINE 4136+ FRECCIABIANCA 8626 | 2:23 PM Rome Ostiense | 3h30 | 5:53 PM Pisa Centrale | 1 transfer | |
ETRUSCHI LINE 4136 | 2:23 PM Rome Ostiense | 4h12 | 6:35 PM Pisa Centrale | 0 transfersDirect | |
Regionale 20683+ FRECCIAROSSA 8524+ TUSCANY LINE 4049 | 2:31 PM Rome Ostiense | 3h30 | 6:01 PM Pisa Centrale | 2 transfers | |
Regionale 20701+ FRECCIAROSSA 1000 9326+ Tuscany Line 18325 | 4:01 PM Rome Ostiense | 3h58 | 7:59 PM Pisa Centrale | 2 transfers | |
ETRUSCHI LINE 4138 | 4:23 PM Rome Ostiense | 3h55 | 8:18 PM Pisa Centrale | 0 transfersDirect | |
Regionale 20709+ FRECCIAROSSA 1000 8528+ Regionale 18329 | 4:31 PM Rome Ostiense | 3h33 | 8:04 PM Pisa Centrale | 2 transfers | |
Regionale 20717+ FRECCIAROSSA 9328+ TUSCANY LINE 18335 | 5:01 PM Rome Ostiense | 3h27 | 8:28 PM Pisa Centrale | 2 transfers | |
Intercity 522 | 5:43 PM Rome Ostiense | 3h07 | 8:50 PM Pisa Centrale | 0 transfersDirect | |
Regionale 20727+ FRECCIARGENTO 8598 | 6:01 PM Rome Ostiense | 2h46 | 8:47 PM Pisa Centrale | 1 transfer | |
ETRUSCHI LINE 4140 | 6:23 PM Rome Ostiense | 3h52 | 10:15 PM Pisa Centrale | 0 transfersDirect | |
Regionale 20387+ FRECCIAROSSA 1000 9674+ Regionale 18251 | 7:25 PM Rome Ostiense | 4h46 | 12:11 AM Pisa Centrale | 2 transfers | |
InterCityNotte 796 | 10:15 PM Rome Ostiense | 3h08 | 1:23 AM Pisa Centrale | 0 transfersDirect | |
| Monday, April 6 | |||||
InterCityNotte 794 | 4:06 AM Rome Ostiense | 3h16 | 7:22 AM Pisa Centrale | 0 transfersDirect | |
ETRUSCHI LINE 4124 | 4:23 AM Rome Ostiense | 3h55 | 8:18 AM Pisa Centrale | 0 transfersDirect | |
ETRUSCHI LINE 4124+ FRECCIAROSSA 8606 | 4:23 AM Rome Ostiense | 3h18 | 7:41 AM Pisa Centrale | 1 transfer | |
Regionale 12505+ FRECCIAROSSA 1000 9406+ TUSCANY LINE 4019 | 5:07 AM Rome Ostiense | 3h28 | 8:35 AM Pisa Centrale | 2 transfers | |
Regionale 12511+ FRECCIAROSSA 9490+ TUSCANY LINE 4021 | 6:06 AM Rome Ostiense | 3h29 | 9:35 AM Pisa Centrale | 2 transfers | |
Regionale 4507+ FRECCIAROSSA 9520+ Regionale 34247 | 6:38 AM Rome Ostiense | 3h26 | 10:04 AM Pisa Centrale | 2 transfers | |
Regionale 12517+ FRECCIAROSSA 1000 9414+ TUSCANY LINE 18287 | 7:07 AM Rome Ostiense | 3h26 | 10:33 AM Pisa Centrale | 2 transfers | |
ETRUSCHI LINE 4128 | 8:23 AM Rome Ostiense | 3h52 | 12:15 PM Pisa Centrale | 0 transfersDirect | |
Regionale 12518+ FRECCIABIANCA 8616 | 9:23 AM Rome Ostiense | 3h26 | 12:49 PM Pisa Centrale | 1 transfer | |
ETRUSCHI LINE 4132 | 10:23 AM Rome Ostiense | 3h52 | 2:15 PM Pisa Centrale | 0 transfersDirect | |
Regionale 5855+ FRECCIAROSSA 9584+ TUSCANY LINE 4037 | 10:39 AM Rome Ostiense | 3h19 | 1:58 PM Pisa Centrale | 2 transfers | |
ETRUSCHI LINE 4134 | 12:23 PM Rome Ostiense | 3h52 | 4:15 PM Pisa Centrale | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome Ostiense to Pisa Centrale by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 06
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Apr 12
Why should you book Rome Ostiense to Pisa Centrale trains with Omio?
Why book with Omio vs Regionale?
- Compare with other providers: On Omio, you can not only buy tickets for Regionale, but also compare tickets for the likes of Intercity Notte, Intercity, Frecciarossa or Frecciabianca to find the best option for your trip from Rome Ostiense to Pisa Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Regionale with all available travel options, which are train and bus to ensure you get the best deal for traveling from Rome Ostiense to Pisa Centrale.
Journey information
Overview: Train from Rome Ostiense to Pisa Centrale
Trains from Rome Ostiense to Pisa Centrale run on average 31 times per day, taking around 3h 8m. Cheap train tickets for this journey start at $16 (€13) but you can travel from only $14 (€11) by bus.
There are 10 trains per day. The earliest train runs at 01:52, the last at 23:15. The fastest train covers the 165 miles (266 km) distance in 3h 7m.
Distance 165 miles (266 km) |
Average train duration 3h 8m |
Cheapest ticket price $16 (€13) |
Trains per day 31 |
Direct trains 10 |
Fastest train 3h 7m |
First train 1:52 AM |
Last train 11:15 PM |
Train companies: Regionale, Intercity Notte, Intercity, Frecciarossa, Frecciabianca, Frecciargento from Rome Ostiense to Pisa Centrale trainsRegionale, Intercity Notte, Intercity, Frecciarossa, Frecciabianca, Frecciargento trains will get you between Rome Ostiense and Pisa Centrale from $14 (€11). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Regionale
Intercity Notte
Intercity
Frecciarossa
Frecciabianca
Frecciargento
FAQs: Trains from Rome Ostiense to Pisa Centrale
Find answers to the most common questions about traveling from Rome Ostiense to Pisa Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Pisa Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Rome Ostiense to Pisa Centrale
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available near the station with both short-term and long-term options.
- Ramen Bar Akira
- Eataly Roma
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €1
- Hotel Abitart
- Hotel San Anselmo
- Hotel Villa San Pio
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-5 for regional and intercity trains
- Hall 2: platforms 6-11 for metropolitan services
- Metro: Line B
- Bus: Several lines available
- Tram: Line 3
- Mon - Sun: 06:00 - 20:30
- There is free Wi-Fi available at the McDonald's.
- There is a luggage storage office near the end of Platform 1.
- McDonald's
- Panetteria Binario 1
- Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
- Hotel NH Pisa
- Hotel La Pace
- Hotel Maria
- Mon - Sun: 06:00 - 20:30
- Located just outside the station on Piazza Vittorio Emanuele II.
- Bus lines: 1
- Train lines: Pisamover (S2), FA, FB, IC, ICN, RV, R, EN
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