The cheapest and fastest trains from Rome Ostiense to Milan Centrale
Cheapest price
$48
Average price
$52
Fastest journey
4 h 13 m
Average duration
6 h 38 m
Trains per day
2
Distance
481 km
The best way to find a cheap train ticket from Rome Ostiense to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome Ostiense to Milan Centrale will cost around $52 if you buy it on the day, but the cheapest tickets can be found for only $48.
Of the 2 trains that leave Rome Ostiense for Milan Centrale on Tue, Apr 07, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Apr 07 the direct trains cover the 481 km distance in an average of 6 h 38 m but if you time it right, some trains will get you there in just 4 h 13 m .
On Tue, Apr 07 the slowest trains will take 9 h 2 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
6:37 PM4h13Rome Ostiense10:50 PMMilan Centrale$481One-way0 transfers
1:23 PM9h02Rome Ostiense10:25 PMMilan Centrale$551One-way0 transfers
6:37 PM4h13Rome Ostiense10:50 PMMilan Centrale$481One-way0 transfers
1:23 PM9h02Rome Ostiense10:25 PMMilan Centrale$551One-way0 transfers
Travel Information
Compare train, bus, and flight for Rome Ostiense to Milan Centrale
Omio recommends booking the train as it is the most popular option from Rome Ostiense to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from $9. For those with little time consider booking a flight which can get you there in 1h 14m. The ticket price range depends on the travel mode: a bus costs an average of $9, and a flight costs an average of $63.
Distance: 298 miles (481 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$55 Average price | $17 Average price Cheapest | $105 Average price |
6h 10m Average total duration 5h 40m Onboard + 30m Additional time* | 8h 29m Average total duration 7h 59m Onboard + 30m Additional time* | 4h 14m Average total duration Fastest 1h 14m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Rome Ostiense to Milan Centrale train times
The table below shows live departures for Rome Ostiense to Milan Centrale trains for today, Monday, April 6. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 12505+ 9972 | On time 5:07 AM Rome Ostiense | 4h08 | 9:15 AM Milan Centrale | 1 transfer | |
Regionale 12505+ FRECCIAROSSA 1000 9612 | 5:07 AM Rome Ostiense | 3h51 | 8:58 AM Milan Centrale | 1 transfer | |
Regionale 12505+ 9912 | On time 5:07 AM Rome Ostiense | 4h13 | 9:20 AM Milan Centrale | 1 transfer | |
Regionale 12505+ 9974 | On time 5:07 AM Rome Ostiense | 5h08 | 10:15 AM Milan Centrale | 1 transfer | |
Regionale 12511+ FRECCIAROSSA 1000 9618 | 6:06 AM Rome Ostiense | 3h52 | 9:58 AM Milan Centrale | 1 transfer | |
Regionale 12511+ 9916 | On time 6:06 AM Rome Ostiense | 4h14 | 10:20 AM Milan Centrale | 1 transfer | |
Regionale 12511+ 9976 | On time 6:06 AM Rome Ostiense | 5h09 | 11:15 AM Milan Centrale | 1 transfer | |
Regionale 12511+ 9974 | On time 6:06 AM Rome Ostiense | 4h09 | 10:15 AM Milan Centrale | 1 transfer | |
Regionale 4507+ 9974 | On time 6:38 AM Rome Ostiense | 3h37 | 10:15 AM Milan Centrale | 1 transfer | |
Regionale 4507+ 9976 | On time 6:38 AM Rome Ostiense | 4h37 | 11:15 AM Milan Centrale | 1 transfer | |
Regionale 4507+ 9978 | On time 6:38 AM Rome Ostiense | 5h37 | 12:15 PM Milan Centrale | 1 transfer | |
Regionale 4507+ FRECCIAROSSA 1000 9620 | 6:38 AM Rome Ostiense | 3h46 | 10:24 AM Milan Centrale | 1 transfer | |
Regionale 12517+ 9920 | On time 7:07 AM Rome Ostiense | 4h13 | 11:20 AM Milan Centrale | 1 transfer | |
Regionale 12517+ 9978 | On time 7:07 AM Rome Ostiense | 5h08 | 12:15 PM Milan Centrale | 1 transfer | |
Regionale 12517+ FRECCIAROSSA 1000 9414 · FRECCIAROSSA 9806 | 7:07 AM Rome Ostiense | 4h18 | 11:25 AM Milan Centrale | 2 transfers | |
Regionale 12517+ 9976 | On time 7:07 AM Rome Ostiense | 4h08 | 11:15 AM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4125+ 9978 | On time 7:37 AM Rome Ostiense | 4h38 | 12:15 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4125+ 9976 | On time 7:37 AM Rome Ostiense | 3h38 | 11:15 AM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4125+ FRECCIAROSSA 9624 | 7:37 AM Rome Ostiense | 3h58 | 11:35 AM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4125+ 9980 | 7:37 AM Rome Ostiense | 5h38 | 1:15 PM Milan Centrale | 1 transfer | |
Regionale 12525+ 9980 | 8:39 AM Rome Ostiense | 4h36 | 1:15 PM Milan Centrale | 1 transfer | |
Regionale 12525+ 9932 | On time 8:39 AM Rome Ostiense | 5h41 | 2:20 PM Milan Centrale | 1 transfer | |
Regionale 12525+ 9978 | On time 8:39 AM Rome Ostiense | 3h36 | 12:15 PM Milan Centrale | 1 transfer | |
Regionale 12525+ FRECCIAROSSA 1000 9514 | 8:39 AM Rome Ostiense | 4h11 | 12:50 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4127+ FRECCIAROSSA 1000 9632 | 9:40 AM Rome Ostiense | 3h55 | 1:35 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4127+ 9932 | On time 9:40 AM Rome Ostiense | 4h40 | 2:20 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4127+ 9984 | On time 9:40 AM Rome Ostiense | 5h35 | 3:15 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4127+ 9980 | 9:40 AM Rome Ostiense | 3h35 | 1:15 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4132 · Regionale TRENORD 10502 · Regionale Veloce TTPER 2486 | 10:23 AM Rome Ostiense | 10h26 | 8:49 PM Milan Centrale | 2 transfers | |
ETRUSCHI LINE 4132 · Regionale TRENORD 10502 · Regionale TRENORD 2186 | 10:23 AM Rome Ostiense | 10h17 | 8:40 PM Milan Centrale | 2 transfers | |
Regionale 5855+ 9982 | 10:39 AM Rome Ostiense | 3h36 | 2:15 PM Milan Centrale | 1 transfer | |
Regionale 5855+ 9984 | On time 10:39 AM Rome Ostiense | 4h36 | 3:15 PM Milan Centrale | 1 transfer | |
Regionale 5855+ 9986 | On time 10:39 AM Rome Ostiense | 5h36 | 4:15 PM Milan Centrale | 1 transfer | |
Regionale 20653 · Regionale Veloce 4737+ 9990 | On time 11:31 AM Rome Ostiense | 6h44 | 6:15 PM Milan Centrale | 2 transfers | |
Regionale 20653 · Regionale Veloce 4737+ 9940 | On time 11:31 AM Rome Ostiense | 4h49 | 4:20 PM Milan Centrale | 2 transfers | |
Regionale 20653 · Regionale Veloce 4737+ 9986 | On time 11:31 AM Rome Ostiense | 4h44 | 4:15 PM Milan Centrale | 2 transfers | |
Regionale 12545+ 9986 | On time 12:07 PM Rome Ostiense | 4h08 | 4:15 PM Milan Centrale | 1 transfer | |
Regionale 12545+ 9940 | On time 12:07 PM Rome Ostiense | 4h13 | 4:20 PM Milan Centrale | 1 transfer | |
Regionale 12545+ 9990 | On time 12:07 PM Rome Ostiense | 6h08 | 6:15 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4134 · Regionale 2296 | 12:23 PM Rome Ostiense | 9h03 | 9:26 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4131+ 9992 | 1:37 PM Rome Ostiense | 5h38 | 7:15 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4131+ FRECCIAROSSA 1000 9648 | 1:37 PM Rome Ostiense | 3h47 | 5:24 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4131+ 9990 | On time 1:37 PM Rome Ostiense | 4h38 | 6:15 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4131+ 9950 | 1:37 PM Rome Ostiense | 3h38 | 5:15 PM Milan Centrale | 1 transfer | |
Intercity 518+ Regionale Veloce 3047 | 1:51 PM Rome Ostiense | 7h44 | 9:35 PM Milan Centrale | 1 transfer | |
Regionale 12551+ 9944 | 2:07 PM Rome Ostiense | 5h38 | 7:45 PM Milan Centrale | 1 transfer | |
Regionale 12551+ 9992 | 2:07 PM Rome Ostiense | 5h08 | 7:15 PM Milan Centrale | 1 transfer | |
Regionale 12551+ 9990 | On time 2:07 PM Rome Ostiense | 4h08 | 6:15 PM Milan Centrale | 1 transfer | |
Regionale 12551+ FRECCIAROSSA 1000 9650 | 2:07 PM Rome Ostiense | 3h51 | 5:58 PM Milan Centrale | 1 transfer | |
Regionale 23265 · Regionale Veloce 4105+ 9992 | 2:26 PM Rome Ostiense | 4h49 | 7:15 PM Milan Centrale | 2 transfers | |
Regionale 23265 · Regionale Veloce 4105+ 9944 | 2:26 PM Rome Ostiense | 5h19 | 7:45 PM Milan Centrale | 2 transfers | |
Regionale 23265 · Regionale Veloce 4105+ 9994 | 2:26 PM Rome Ostiense | 5h49 | 8:15 PM Milan Centrale | 2 transfers | |
ETRUSCHI LINE 4133+ 9944 | 3:37 PM Rome Ostiense | 4h08 | 7:45 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4133+ 9994 | 3:37 PM Rome Ostiense | 4h38 | 8:15 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4133+ 9992 | 3:37 PM Rome Ostiense | 3h38 | 7:15 PM Milan Centrale | 1 transfer | |
Regionale 12555+ FRECCIAROSSA 1000 9662 | 4:06 PM Rome Ostiense | 3h54 | 8:00 PM Milan Centrale | 1 transfer | |
Regionale 12555+ 9954 | 4:06 PM Rome Ostiense | 4h14 | 8:20 PM Milan Centrale | 1 transfer | |
Regionale 12555+ 9994 | 4:06 PM Rome Ostiense | 4h09 | 8:15 PM Milan Centrale | 1 transfer | |
Regionale 12555+ 9996 | 4:06 PM Rome Ostiense | 5h09 | 9:15 PM Milan Centrale | 1 transfer | |
Regionale 4511+ 9994 | 4:39 PM Rome Ostiense | 3h36 | 8:15 PM Milan Centrale | 1 transfer | |
Regionale 4511+ 8158 | 4:39 PM Rome Ostiense | 4h41 | 9:20 PM Milan Centrale | 1 transfer | |
Regionale 4511+ FRECCIAROSSA 1000 9560 | 4:39 PM Rome Ostiense | 4h11 | 8:50 PM Milan Centrale | 1 transfer | |
Regionale 4511+ 9996 | 4:39 PM Rome Ostiense | 4h36 | 9:15 PM Milan Centrale | 1 transfer | |
Regionale 12557+ 8158 | 5:07 PM Rome Ostiense | 4h13 | 9:20 PM Milan Centrale | 1 transfer | |
Regionale 12557+ 9996 | 5:07 PM Rome Ostiense | 4h08 | 9:15 PM Milan Centrale | 1 transfer | |
Regionale 12557+ 9962 | 5:07 PM Rome Ostiense | 5h13 | 10:20 PM Milan Centrale | 1 transfer | |
Regionale 12557+ FRECCIAROSSA 9668 | 5:07 PM Rome Ostiense | 3h53 | 9:00 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4135+ FRECCIAROSSA 9592 | 5:37 PM Rome Ostiense | 4h13 | 9:50 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4135+ 9962 | 5:37 PM Rome Ostiense | 4h43 | 10:20 PM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4135+ 9996 | 5:37 PM Rome Ostiense | 3h38 | 9:15 PM Milan Centrale | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Rome Ostiense to Milan Centrale by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 07
Apr 08
Apr 09
Apr 10
Apr 11
Apr 12
Apr 13
Why should you book Rome Ostiense to Milan Centrale trains with Omio?
Why book with Omio vs Frecciarossa?
- Compare with other providers: On Omio, you can not only buy tickets for Frecciarossa, but also compare tickets for the likes of Italo, Intercity Notte, Intercity or Regionale to find the best option for your trip from Rome Ostiense to Milan Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Frecciarossa with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome Ostiense to Milan Centrale.
Why book with Omio over Raileurope?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome Ostiense to Milan Centrale.
Journey information
Overview: Train from Rome Ostiense to Milan Centrale
Trains from Rome Ostiense to Milan Centrale run on average 29 times per day, taking around 5h 40m. Cheap train tickets for this journey start at $35 (€28) but you can travel from only $9 (€7) by bus.
There are 1 trains per day. The earliest train runs at 05:48, the last at 23:15. The fastest train covers the 298 miles (481 km) distance in 4h 13m.
Distance 298 miles (481 km) |
Average train duration 5h 40m |
Cheapest ticket price $35 (€28) |
Trains per day 29 |
Direct trains 1 |
Fastest train 4h 13m |
First train 5:48 AM |
Last train 11:15 PM |
Train companies: Frecciarossa, Italo, Intercity Notte, Intercity, Regionale from Rome Ostiense to Milan Centrale trainsFrecciarossa, Italo, Intercity Notte, Intercity, Regionale trains will get you between Rome Ostiense and Milan Centrale from $9 (€7). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
Italo
Intercity Notte
Intercity
Regionale
FAQs: Trains from Rome Ostiense to Milan Centrale
Find answers to the most common questions about traveling from Rome Ostiense to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Rome Ostiense to Milan Centrale
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available near the station with both short-term and long-term options.
- Ramen Bar Akira
- Eataly Roma
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €1
- Hotel Abitart
- Hotel San Anselmo
- Hotel Villa San Pio
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-5 for regional and intercity trains
- Hall 2: platforms 6-11 for metropolitan services
- Metro: Line B
- Bus: Several lines available
- Tram: Line 3
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
More options for your journey from Rome Ostiense to Milan Centrale
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