Travel Information
Compare train, bus, and flight for Florence to Lyon
Omio recommends booking the bus as it is the most popular option from Florence to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $22. For those with little time consider booking a flight which can get you there in 2h 50m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.6 - 1.4kg. The ticket price range depends on the travel mode: a bus costs an average of $22, and a flight costs an average of $48.
Distance: 342 miles (551 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$46 Average price Cheapest | $140 Average price | $211 Average price |
14h 5m Average total duration 13h 35m Onboard + 30m Additional time* | 8h 44m Average total duration 8h 14m Onboard + 30m Additional time* | 5h 50m Average total duration Fastest 2h 50m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions Lowest | - CO2 emissions | 1.7 - 3.3kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Florence to Lyon
How to get from Florence to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Florence to Lyon is by taking a bus because it’s the best combination of price and speed.
38981:05 AM11h50Scandicci, Villa Costanza (Florence)12:55 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$361One-way0 transfers
Cheapest
38981:05 AM11h50Scandicci, Villa Costanza (Florence)12:55 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$361One-way0 transfers
Fastest
LH9439+
LH22501:20 PM3h45Florence Peretola Airport5:05 PMLyon Saint Exupery Airport$3721One-way1 transfer
Other options
Regionale 17816 · Regionale Veloce TTPER 2470+
FRECCIAROSSA 1000 92968:41 AM11h51Florence Rifredi8:32 PMLyon Part Dieu$2001One-way2 transfers
9928+
FRECCIAROSSA 1000 92961:25 PM7h07Florence Santa Maria Novella8:32 PMLyon Part Dieu$2221One-way1 transfer
Tuscany Line 18502 · Regionale 17808 · Regionale Veloce TTPER 2466+
FRECCIAROSSA 1000 92967:09 AM13h23Florence Santa Maria Novella8:32 PMLyon Part Dieu$2001One-way3 transfers
349210:20 AM11h10Scandicci, Villa Costanza (Florence)9:30 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$491One-way0 transfers
FlixBus12:00 PM10h40Scandicci, Villa Costanza (Florence)10:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$541One-way0 transfers
947422:15 PM11h05Scandicci, Villa Costanza (Florence)1:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$501One-way0 transfers
AF1567 · AF73703:20 PM6h05Florence Peretola Airport9:25 PMLyon Saint Exupery Airport$2611One-way1 transfer
AF1467 · AF73701:05 PM8h20Florence Peretola Airport9:25 PMLyon Saint Exupery Airport$3041One-way1 transfer
AF1367 · AF737012:15 PM9h10Florence Peretola Airport9:25 PMLyon Saint Exupery Airport$3141One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Florence to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Florence to Lyon.

This is compared to other travel options from Florence to Lyon:
A bus is $26 (€21) less than a flight for this route with tickets for a flight from Florence to Lyon costing on average $48 (€39).
A bus is $76 (€62) less than a train for this route with tickets for a train from Florence to Lyon costing on average $98 (€80).
Other travel options to Lyon take longer:
Train takes on average 7h 12m.
Bus takes on average 10h 40m.
- Around 25 flights per day.
- Around 15 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Florence and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Florence Peretola Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Florence Santa Maria Novella and arrive in Lyon Part Dieu.
- Buses mostly depart from Scandicci, Villa Costanza (Florence) and arrive in Lyon, Perrache Bus Station.
- Travel with Volotea, Air France, Vueling, Air Dolomiti, Lufthansa Cityline, KLM Cityhopper to go to Lyon by flight.
- Travel with Trenitalia, Frecciarossa, Intercity Notte, SNCF | TGV INOUI, Regionale, Intercity, Italo to go to Lyon by train.
- Travel with BlaBlaCar Bus, FlixBus, Itabus, BlaBlaCar to go to Lyon by bus.
- 6 direct buses per day with BlaBlaCar Bus, FlixBus, Itabus, BlaBlaCar.
Travelling from Florence to Lyon: related information
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