Travel Information
Compare train, bus, and flight for Prague to Lyon
Omio recommends booking the flight as it is the most popular option from Prague to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $57. For those with little time consider booking a flight which can get you there in 2h 42m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of $57, and a train costs an average of $273.
Distance: 534 miles (860 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
$186 Average price | $85 Average price Cheapest | $309 Average price |
5h 42m Average total duration Fastest 2h 42m Onboard + 3h 0m Additional time* | 17h 2m Average total duration 16h 32m Onboard + 30m Additional time* | 14h 30m Average total duration 14h 0m Onboard + 30m Additional time* |
2.6 - 5.2kg CO2 emissions | 0.9 - 2.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Prague to Lyon
How to get from Prague to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Prague to Lyon is by taking a bus because it’s the best combination of price and speed.
FlixBus9:50 PM14h50Praha, Na Knížecí12:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1431One-way0 transfers
Cheapest
FlixBus6:40 AM16h35Praha, ÚAN Florenc11:15 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1381One-way0 transfers
Fastest
SN2812+
SN35936:45 PM3h35Prague Vaclav Havel Airport10:20 PMLyon Saint Exupery Airport$6721One-way1 transfer
Other options
FlixBus9:25 PM15h15Praha, ÚAN Florenc12:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1431One-way0 transfers
FlixBus · FlixBus11:50 PM21h00Prague, Central Train Station8:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1451One-way1 transfer
FlixBus · FlixBus4:10 AM19h05Praha, Na Knížecí11:15 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1501One-way1 transfer
LH1691 · LH22501:25 PM3h40Prague Vaclav Havel Airport5:05 PMLyon Saint Exupery Airport$3731One-way1 transfer
LH1393 · LH10769:10 AM4h20Prague Vaclav Havel Airport1:30 PMLyon Saint Exupery Airport$3831One-way1 transfer
OS650 · OS3537:30 AM4h40Prague Vaclav Havel Airport12:10 PMLyon Saint Exupery Airport$3801One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Prague to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Lyon.

This is compared to other travel options from Prague to Lyon:
A flight is $5 (€4) less than a bus for this route with tickets for a bus from Prague to Lyon costing on average $57 (€46).
A flight is $221 (€179) less than a train for this route with tickets for a train from Prague to Lyon costing on average $273 (€221).
Other travel options to Lyon take longer:
Train takes on average 13h 27m.
Bus takes on average 14h 35m.
- Around 38 flights per day.
- Around 12 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Prague and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Lyon Part Dieu.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Lyon, Perrache Bus Station.
- Travel with Volotea, easyJet, Lufthansa, Brussels Airlines, Air France, Air Dolomiti, Lufthansa Cityline, Austrian Airlines, KLM, KLM Cityhopper, Vueling Airlines, Air Baltic, LOT Polish Airlines to go to Lyon by flight.
- Travel with FlixBus, BlaBlaCar Bus to go to Lyon by bus.
- Travel with Deutsche Bahn, ÖBB | Euro City (EC) to go to Lyon by train.
- 6 direct buses per day with FlixBus, BlaBlaCar Bus.
Travelling from Prague to Lyon: related information
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